New clinical trial designs in the era of precision medicine

by Elena Garralda, Rodrigo Dienstmann, Alejandro Piris‐Giménez, Irene Braña, Jordi Rodon, Josep Tabernero
Published 2019-03-01

Mechanisms of Resistance to PI3K Inhibitors in Cancer: Adaptive Responses, Drug Tolerance and Cellular Plasticity

by Sarah Christine Elisabeth Wright, Natali Vasilevski, Violeta Serra, Jordi Rodon, Pieter Johan Adam Eichhorn
Published 2021-03-01

The co-management of the sand eel fishery of Catalonia (NW Mediterranean): the story of a process

by Jordi Lleonart, Montserrat Demestre, Paloma Martín, Jordi Rodón, Susana Sainz-Trápaga, Pilar Sánchez, Itziar Segarra, Sergi Tudela
Published 2014-03-01

Type I and III IFNs produced by the nasal epithelia and dimmed inflammation are features of alpacas resolving MERS-CoV infection.

by Nigeer Te, Jordi Rodon, Maria Ballester, Mónica Pérez, Lola Pailler-García, Joaquim Segalés, Júlia Vergara-Alert, Albert Bensaid
Published 2021-05-01

R1507, an anti-insulin-like growth factor-1 receptor (IGF-1R) antibody, and EWS/FLI-1 siRNA in Ewing's sarcoma: convergence at the IGF/IGFR/Akt axis.

by Helen J Huang, Laura S Angelo, Jordi Rodon, Michael Sun, Klaus-Peter Kuenkele, Henrique A Parsons, Jonathan C Trent, Razelle Kurzrock
Published 2011-01-01

Relative bioavailability of three formulations of galunisertib administered as monotherapy in patients with advanced or metastatic cancer

by Ivelina Gueorguieva, Ann Cleverly, Durisala Desaiah, Analia Azaro, Joan Seoane, Irene Braña, Elisabet Sicart, Colin Miles, Michael M Lahn, Malcolm I Mitchell, Jordi Rodon
Published 2016-12-01

8 Immune correlates associated with clinical outcomes in patients with advanced malignancies treated with avelumab and OX40 agonist

by Heather Lin, Fei Yang, Siqing Fu, Joud Hajjar, Daniel Karp, Bettzy Stephen, Ignacio Wistuba, Yeonjoo Choi, Cheuk Hong Leung, Jordi Rodon, Edwin Parra, Naval Daver, Yali Yang
Published 2020-11-01

283 Safety and efficacy signals in the complete phase I study of live biotherapeutic MRx0518 in combination with pembrolizumab in patients refractory to immune checkpoint inhibitor...

by Alexander Stevenson, Jianjun Gao, Pavlos Msaouel, Nizar Tannir, Mehmet Altan, Shi-Ming Tu, Michael Chisamore, Matthew Campbell, George Blumenschein, Xiuning Le, Frank Mott, Amishi Shah, Jordi Rodon, Imke Mulder
Published 2020-11-01

Phase II Clinical Trial of Pembrolizumab in Patients with Progressive Metastatic Pheochromocytomas and Paragangliomas

by Camilo Jimenez, Vivek Subbiah, Bettzy Stephen, Junsheng Ma, Denai Milton, Mingxuan Xu, Abdualrazzak Zarifa, Fechukwu Omolara Akhmedzhanov, Apostolia Tsimberidou, Mouhammed Amir Habra, Jordi Rodon Anhert, Siqing Fu, Aung Naing
Published 2020-08-01

Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations

by David Tamborero, Carlota Rubio-Perez, Jordi Deu-Pons, Michael P. Schroeder, Ana Vivancos, Ana Rovira, Ignasi Tusquets, Joan Albanell, Jordi Rodon, Josep Tabernero, Carmen de Torres, Rodrigo Dienstmann, Abel Gonzalez-Perez, Nuria Lopez-Bigas
Published 2018-03-01

Evaluating the psychometric properties of the Immunotherapy module of the MD Anderson Symptom Inventory

by Mehmet Altan, Lilibeth Castillo, Bettzy Stephen, Sarina A Piha-Paul, Tito Mendoza, Goldy George, Enedelia Rodriguez, Christine Peterson, Jordi Rodon Ahnert, Timonthy A Yap, Apostolia M Tsimberidou, Daniel D Karp, Abdulrazzak Zarifa, Lacey M McQuinn, Charles Cleeland
Published 2020-07-01

Author response to Cunha et al

by Vivek Subbiah, Sara Ahmed, Christian Rolfo, Aung Naing, Joud Hajjar, Bettzy Stephen, Jordi Rodon Ahnert, Daniel D Karp, Rivka R Colen, Murat Ak, Mira Ayoub, Nabil Elshafeey, Priyadarshini Mamindla, Pascal O Zinn, Chaan Ng, Raghu Vikram, Spyridon Bakas, Christine B Peterson
Published 2021-07-01

Phase II clinical trial of pembrolizumab efficacy and safety in advanced adrenocortical carcinoma

by Mouhammed Amir Habra, Bettzy Stephen, Matthew Campbell, Kenneth Hess, Coya Tapia, Mingxuan Xu, Jordi Rodon Ahnert, Camilo Jimenez, Jeffrey E. Lee, Nancy D. Perrier, Russell R. Boraddus, Shubham Pant, Vivek Subbiah, David S. Hong, Abdulrazzak Zarifa, Siqing Fu, Daniel D. Karp, Funda Meric-Bernstam, Aung Naing
Published 2019-09-01

Monitoring Natural SARS-CoV-2 Infection in Lions (<i>Panthera leo</i>) at the Barcelona Zoo: Viral Dynamics and Host Responses

by Hugo Fernández-Bellon, Jordi Rodon, Leira Fernández-Bastit, Vanessa Almagro, Pilar Padilla-Solé, Cristina Lorca-Oró, Rosa Valle, Núria Roca, Santina Grazioli, Tiziana Trogu, Albert Bensaid, Jorge Carrillo, Nuria Izquierdo-Useros, Julià Blanco, Mariona Parera, Marc Noguera-Julián, Bonaventura Clotet, Ana Moreno, Joaquim Segalés, Júlia Vergara-Alert
Published 2021-08-01

Phase 2 study of buparlisib (BKM120), a pan-class I PI3K inhibitor, in patients with metastatic triple-negative breast cancer

by Ana C. Garrido-Castro, Cristina Saura, Romualdo Barroso-Sousa, Hao Guo, Eva Ciruelos, Begoña Bermejo, Joaquin Gavilá, Violeta Serra, Aleix Prat, Laia Paré, Pamela Céliz, Patricia Villagrasa, Yisheng Li, Jennifer Savoie, Zhan Xu, Carlos L. Arteaga, Ian E. Krop, David B. Solit, Gordon B. Mills, Lewis C. Cantley, Eric P. Winer, Nancy U. Lin, Jordi Rodon
Published 2020-11-01

Previous SARS-CoV-2 Infection Increases B.1.1.7 Cross-Neutralization by Vaccinated Individuals

by Benjamin Trinité, Edwards Pradenas, Silvia Marfil, Carla Rovirosa, Víctor Urrea, Ferran Tarrés-Freixas, Raquel Ortiz, Jordi Rodon, Júlia Vergara-Alert, Joaquim Segalés, Victor Guallar, Rosalba Lepore, Nuria Izquierdo-Useros, Glòria Trujillo, Jaume Trapé, Carolina González-Fernández, Antonia Flor, Rafel Pérez-Vidal, Ruth Toledo, Anna Chamorro, Roger Paredes, Ignacio Blanco, Eulàlia Grau, Marta Massanella, Jorge Carrillo, Bonaventura Clotet, Julià Blanco
Published 2021-06-01

SARS-CoV-2 infection elicits a rapid neutralizing antibody response that correlates with disease severity

by Benjamin Trinité, Ferran Tarrés-Freixas, Jordi Rodon, Edwards Pradenas, Víctor Urrea, Silvia Marfil, María Luisa Rodríguez de la Concepción, Carlos Ávila-Nieto, Carmen Aguilar-Gurrieri, Ana Barajas, Raquel Ortiz, Roger Paredes, Lourdes Mateu, Alfonso Valencia, Víctor Guallar, Lidia Ruiz, Eulàlia Grau, Marta Massanella, Jordi Puig, Anna Chamorro, Nuria Izquierdo-Useros, Joaquim Segalés, Bonaventura Clotet, Jorge Carrillo, Júlia Vergara-Alert, Julià Blanco
Published 2021-01-01

Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen

by Jordi Rodon, Jordana Muñoz-Basagoiti, Daniel Perez-Zsolt, Marc Noguera-Julian, Marc Noguera-Julian, Roger Paredes, Roger Paredes, Lourdes Mateu, Carles Quiñones, Carles Perez, Itziar Erkizia, Ignacio Blanco, Alfonso Valencia, Alfonso Valencia, Víctor Guallar, Víctor Guallar, Jorge Carrillo, Julià Blanco, Julià Blanco, Julià Blanco, Joaquim Segalés, Joaquim Segalés, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, Júlia Vergara-Alert, Nuria Izquierdo-Useros, Nuria Izquierdo-Useros
Published 2021-03-01

9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapy

by Guangchun Han, Guoliang Yang, Dapeng Hao, Yang Lu, Kyaw Thein, Benjamin S. Simpson, Jianfeng Chen, Ryan Sun, Omar Alhalabi, Ruiping Wang, Minghao Dang, Enyu Dai, Shaojun Zhang, Fengqi Nie, Shuangtao Zhao, Charles Guo, Ameer Hamza, Bogdan Czerniak, Chao Cheng, Arlene Siefker-Radtke, Krishna Bhat, Andrew Futreal, Guang Peng, Jennifer Wargo, Weiyi Peng, Humam Kadara, Jaffer Ajani, Charles Swanton, Kevin Litchfield, Jordi Rodon Ahnert, Jianjun Gao, Linghua Wang
Published 2021-09-01