The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic Opportunities

by Jacopo Boni, Carlota Rubio-Perez, Nuria López-Bigas, Cristina Fillat, Susana de la Luna
Published 2020-07-01

Genetic and functional characterization of disease associations explains comorbidity

by Carlota Rubio-Perez, Emre Guney, Daniel Aguilar, Janet Piñero, Javier Garcia-Garcia, Barbara Iadarola, Ferran Sanz, Narcís Fernandez-Fuentes, Laura I. Furlong, Baldo Oliva
Published 2017-07-01

Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations

by David Tamborero, Carlota Rubio-Perez, Jordi Deu-Pons, Michael P. Schroeder, Ana Vivancos, Ana Rovira, Ignasi Tusquets, Joan Albanell, Jordi Rodon, Josep Tabernero, Carmen de Torres, Rodrigo Dienstmann, Abel Gonzalez-Perez, Nuria Lopez-Bigas
Published 2018-03-01

Independent Component Analysis Uncovers the Landscape of the Bladder Tumor Transcriptome and Reveals Insights into Luminal and Basal Subtypes

by Anne Biton, Isabelle Bernard-Pierrot, Yinjun Lou, Clémentine Krucker, Elodie Chapeaublanc, Carlota Rubio-Pérez, Nuria López-Bigas, Aurélie Kamoun, Yann Neuzillet, Pierre Gestraud, Luca Grieco, Sandra Rebouissou, Aurélien de Reyniès, Simone Benhamou, Thierry Lebret, Jennifer Southgate, Emmanuel Barillot, Yves Allory, Andrei Zinovyev, François Radvanyi
Published 2014-11-01

Circulating tumour DNA from the cerebrospinal fluid allows the characterisation and monitoring of medulloblastoma

by Laura Escudero, Anna Llort, Alexandra Arias, Ander Diaz-Navarro, Francisco Martínez-Ricarte, Carlota Rubio-Perez, Regina Mayor, Ginevra Caratù, Elena Martínez-Sáez, Élida Vázquez-Méndez, Iván Lesende-Rodríguez, Raquel Hladun, Luis Gros, Santiago Ramón y Cajal, Maria A. Poca, Xose S. Puente, Juan Sahuquillo, Soledad Gallego, Joan Seoane
Published 2020-10-01

Single-cell transcriptional changes associated with drug tolerance and response to combination therapies in cancer

by Alexandre F. Aissa, Abul B. M. M. K. Islam, Majd M. Ariss, Cammille C. Go, Alexandra E. Rader, Ryan D. Conrardy, Alexa M. Gajda, Carlota Rubio-Perez, Klara Valyi-Nagy, Mary Pasquinelli, Lawrence E. Feldman, Stefan J. Green, Nuria Lopez-Bigas, Maxim V. Frolov, Elizaveta V. Benevolenskaya
Published 2021-03-01

Immune cell profiling of the cerebrospinal fluid enables the characterization of the brain metastasis microenvironment

by Carlota Rubio-Perez, Ester Planas-Rigol, Juan L. Trincado, Ester Bonfill-Teixidor, Alexandra Arias, Domenica Marchese, Catia Moutinho, Garazi Serna, Leire Pedrosa, Raffaella Iurlaro, Francisco Martínez-Ricarte, Laura Escudero, Esteban Cordero, Marta Cicuendez, Sara Ruiz, Genís Parra, Paolo Nuciforo, Josep Gonzalez, Estela Pineda, Juan Sahuquillo, Josep Tabernero, Holger Heyn, Joan Seoane
Published 2021-03-01

LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy

by Mónica Pascual-García, Ester Bonfill-Teixidor, Ester Planas-Rigol, Carlota Rubio-Perez, Raffaella Iurlaro, Alexandra Arias, Isabel Cuartas, Ada Sala-Hojman, Laura Escudero, Francisco Martínez-Ricarte, Isabel Huber-Ruano, Paolo Nuciforo, Leire Pedrosa, Carolina Marques, Irene Braña, Elena Garralda, María Vieito, Massimo Squatrito, Estela Pineda, Francesc Graus, Carmen Espejo, Juan Sahuquillo, Josep Tabernero, Joan Seoane
Published 2019-06-01