Independent domains for recruitment of PRC1 and PRC2 by human XIST.

by Thomas Dixon-McDougall, Carolyn J Brown
Published 2021-03-01

Causal inference for heritable phenotypic risk factors using heterogeneous genetic instruments.

by Jingshu Wang, Qingyuan Zhao, Jack Bowden, Gibran Hemani, George Davey Smith, Dylan S Small, Nancy R Zhang
Published 2021-06-01

Identification of multiple odorant receptors essential for pyrethrum repellency in Drosophila melanogaster.

by Qiang Wang, Peng Xu, Felipe Andreazza, Yahui Liu, Yoshiko Nomura, Phil Duran, Lan Jiang, Mengli Chen, Genki Takamatsu, Makoto Ihara, Kazuhiko Matsuda, Rufus Isaacs, Eugenio E Oliveira, Yuzhe Du, Ke Dong
Published 2021-07-01

A homozygous stop-gain variant in ARHGAP42 is associated with childhood interstitial lung disease, systemic hypertension, and immunological findings.

by Qifei Li, Michal Dibus, Alicia Casey, Christina S K Yee, Sara O Vargas, Shiyu Luo, Samantha M Rosen, Jill A Madden, Casie A Genetti, Jan Brabek, Catherine A Brownstein, Shideh Kazerounian, Benjamin A Raby, Klaus Schmitz-Abe, John C Kennedy, Martha P Fishman, Mary P Mullen, Joan M Taylor, Daniel Rosel, Pankaj B Agrawal
Published 2021-07-01

CREB mediates the C. elegans dauer polyphenism through direct and cell-autonomous regulation of TGF-β expression.

by JiSoo Park, Hyekyoung Oh, Do-Young Kim, YongJin Cheon, Yeon-Ji Park, Hyeonjeong Hwang, Scott J Neal, Abdul Rouf Dar, Rebecca A Butcher, Piali Sengupta, Dae-Won Kim, Kyuhyung Kim
Published 2021-07-01

The H3.3K27M oncohistone antagonizes reprogramming in Drosophila.

by Kami Ahmad, Steven Henikoff
Published 2021-07-01

Rad21l1 cohesin subunit is dispensable for spermatogenesis but not oogenesis in zebrafish.

by Yana P Blokhina, Michelle A Frees, An Nguyen, Masuda Sharifi, Daniel B Chu, Kristi Bispo, Ivan Olaya, Bruce W Draper, Sean M Burgess
Published 2021-06-01

Pch2 orchestrates the meiotic recombination checkpoint from the cytoplasm.

by Esther Herruzo, Ana Lago-Maciel, Sara Baztán, Beatriz Santos, Jesús A Carballo, Pedro A San-Segundo
Published 2021-07-01

Transcriptomic and epigenomic profiling of young and aged spermatogonial stem cells reveals molecular targets regulating differentiation.

by Jinyue Liao, Hoi Ching Suen, Alfred Chun Shui Luk, Lele Yang, Annie Wing Tung Lee, Huayu Qi, Tin-Lap Lee
Published 2021-07-01

Nuclear receptors NHR-49 and NHR-79 promote peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans.

by Lidan Zeng, Xuesong Li, Christopher B Preusch, Gary J He, Ningyi Xu, Tom H Cheung, Jianan Qu, Ho Yi Mak
Published 2021-07-01

What connectomics can learn from genomics.

by Patrick B Chen, Jonathan Flint
Published 2021-07-01

Genome mapping coupled with CRISPR gene editing reveals a P450 gene confers avermectin resistance in the beet armyworm.

by Yayun Zuo, Yu Shi, Feng Zhang, Fang Guan, Jianpeng Zhang, René Feyereisen, Jeffrey A Fabrick, Yihua Yang, Yidong Wu
Published 2021-07-01

Quantitative mapping of mRNA 3' ends in Pseudomonas aeruginosa reveals a pervasive role for premature 3' end formation in response to azithromycin.

by Salini Konikkat, Michelle R Scribner, Rory Eutsey, N Luisa Hiller, Vaughn S Cooper, Joel McManus
Published 2021-07-01

DAF-18/PTEN inhibits germline zygotic gene activation during primordial germ cell quiescence.

by Amanda L Fry, Amy K Webster, Julia Burnett, Rojin Chitrakar, L Ryan Baugh, E Jane Albert Hubbard
Published 2021-07-01

Diverse LXG toxin and antitoxin systems specifically mediate intraspecies competition in Bacillus subtilis biofilms.

by Kazuo Kobayashi
Published 2021-07-01

The blood flow-klf6a-tagln2 axis drives vessel pruning in zebrafish by regulating endothelial cell rearrangement and actin cytoskeleton dynamics.

by Lin Wen, Tao Zhang, Jinxuan Wang, Xuepu Jin, Muhammad Abdul Rouf, Desha Luo, Yuan Zhu, Daoxi Lei, Hans Gregersen, Yeqi Wang, Guixue Wang
Published 2021-07-01

A spectral theory for Wright's inbreeding coefficients and related quantities.

by Olivier François, Clément Gain
Published 2021-07-01

The selfish yeast plasmid utilizes the condensin complex and condensed chromatin for faithful partitioning.

by Deepanshu Kumar, Hemant Kumar Prajapati, Anjali Mahilkar, Chien-Hui Ma, Priyanka Mittal, Makkuni Jayaram, Santanu K Ghosh
Published 2021-07-01

Powerful detection of polygenic selection and evidence of environmental adaptation in US beef cattle.

by Troy N Rowan, Harly J Durbin, Christopher M Seabury, Robert D Schnabel, Jared E Decker
Published 2021-07-01

Caenorhabditis elegans RMI2 functional homolog-2 (RMIF-2) and RMI1 (RMH-1) have both overlapping and distinct meiotic functions within the BTR complex.

by Maria Velkova, Nicola Silva, Maria Rosaria Dello Stritto, Alexander Schleiffer, Pierre Barraud, Markus Hartl, Verena Jantsch
Published 2021-07-01