Discovery of novel anxiolytic agents — The trials and tribulations of pre-clinical models of anxiety

by N.A. Andrews, M. Papakosta, N.M. Barnes
Published 2014-01-01

The hallmarks of ovarian cancer: Focus on angiogenesis and micro-environment and new models for their characterisation

by V. Heredia-Soto, J.A. López-Guerrero, A. Redondo, M. Mendiola
Published 2020-08-01

Effect of voluntary running activity on mRNA expression of extracellular matrix genes in a mouse model of intervertebral disc degeneration

by Seon Ho Jang, Seunghwan Lee, Magali Millecamps, Alexander Danco, HyungMo Kang, Stéphanie Grégoire, Miyako Suzuki‐Narita, Laura S. Stone
Published 2021-09-01

Development of a standardized histopathology scoring system using machine learning algorithms for intervertebral disc degeneration in the mouse model—An ORS spine section initiativ...

by Itzel Paola Melgoza, Srish S. Chenna, Steven Tessier, Yejia Zhang, Simon Y. Tang, Takashi Ohnishi, Emanuel José Novais, Geoffrey J. Kerr, Sarthak Mohanty, Vivian Tam, Wilson C. W. Chan, Chao‐Ming Zhou, Ying Zhang, Victor Y. Leung, Angela K. Brice, Cheryle A. Séguin, Danny Chan, Nam Vo, Makarand V. Risbud, Chitra L. Dahia
Published 2021-06-01

Does the Microenvironment Hold the Hidden Key for Functional Precision Medicine in Pancreatic Cancer?

by John Kokkinos, Anya Jensen, George Sharbeen, Joshua A. McCarroll, David Goldstein, Koroush S. Haghighi, Phoebe A. Phillips
Published 2021-05-01

The Pre-clinical Toolbox of Pharmacokinetics and Pharmacodynamics: in vitro and ex vivo Models

by Carolina Herrera
Published 2019-05-01

Maternal Distress and Offspring Neurodevelopment: Challenges and Opportunities for Pre-clinical Research Models

by Eamon Fitzgerald, Eamon Fitzgerald, Carine Parent, Carine Parent, Michelle Z. L. Kee, Michael J. Meaney, Michael J. Meaney, Michael J. Meaney, Michael J. Meaney
Published 2021-02-01

Radiation Metabolomics: Current Status and Future Directions

by Smrithi eSugumaran Menon, Medha eUppal, Subeena eRandhawa, Mehar eCheema, Nima eAghdam, Rachel L. Usala, Sanchita eGhosh, Amrita K Cheema, Anatoly eDritschilo
Published 2016-02-01

Strengths and Weaknesses of Pre-Clinical Models for Human Melanoma Treatment: Dawn of Dogs’ Revolution for Immunotherapy

by Giuseppina Barutello, Valeria Rolih, Maddalena Arigoni, Lidia Tarone, Laura Conti, Elena Quaglino, Paolo Buracco, Federica Cavallo, Federica Riccardo
Published 2018-03-01

Meibomian Gland Dysfunction in Ocular Graft vs. Host Disease: A Need for Pre-Clinal Models and Deeper Insights

by Eugene Appenteng Osae, Philipp Steven
Published 2021-03-01

At the intersection of science and theory: How the Nurse Role Integration Model reconciles the conflict

by Sharon G. Casavant, PhD, RN
Published 2020-07-01

Patient-derived xenograft models to improve targeted therapy in epithelial ovarian cancer treatment

by Clare eScott, Clare eScott, Clare eScott, Marc A. Becker, Paul eHaluska, Goli eSamimi, Goli eSamimi
Published 2013-12-01

Mouse models of myeloproliferative neoplasms for pre-clinical testing of novel therapeutic agents

by Jan Stetka, Radek C. Skoda
Published 2021-03-01

Insights From Pre-Clinical and Clinical Studies on the Role of Innate Inflammation in Atherosclerosis Regression

by Karishma Rahman, Edward A. Fisher
Published 2018-05-01

Refinement of an Established Procedure and Its Application for Identification of Hypoxia in Prostate Cancer Xenografts

by Pernille B. Elming, Thomas R. Wittenborn, Morten Busk, Brita S. Sørensen, Mathilde Borg Houlberg Thomsen, Trine Strandgaard, Lars Dyrskjøt, Steffen Nielsen, Michael R. Horsman
Published 2021-05-01

Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical models

by Jonathan E. Millar, Nicole Bartnikowski, Viktor von Bahr, Maximilian V. Malfertheiner, Nchafatso G. Obonyo, Mirko Belliato, Jacky Y. Suen, Alain Combes, Daniel F. McAuley, Roberto Lorusso, John F. Fraser, on behalf of the European Extracorporeal Life Support Organisation (EuroELSO) Innovations Workgroup, the National Health Medical Research Council Australia Centre of Research Excellence for Advanced Cardio-respiratory Therapies Improving Organ Support (NHMRC CREACTIONS)
Published 2019-03-01

Current State and Challenges in Development of Targeted Therapies in Myelodysplastic Syndromes (MDS)

by Michele Stanchina, Sana Chaudhry, Matthew Karr, Justin Taylor
Published 2021-04-01

Patient-Derived Organoid Models of Human Neuroendocrine Carcinoma

by Krijn K. Dijkstra, Krijn K. Dijkstra, José G. van den Berg, Fleur Weeber, Fleur Weeber, Joris van de Haar, Joris van de Haar, Arno Velds, Sovann Kaing, Sovann Kaing, Dennis D. G. C. Peters, Ferry A. L. M. Eskens, Derk-Jan A. de Groot, Margot E. T. Tesselaar, Emile E. Voest, Emile E. Voest
Published 2021-03-01

Patient-derived tumor models: a more suitable tool for pre-clinical studies in colorectal cancer

by Giulia Rizzo, Andrea Bertotti, Simonetta Maria Leto, Stefania Vetrano
Published 2021-06-01

SRSF1-dependent inhibition of C9ORF72-repeat RNA nuclear export: genome-wide mechanisms for neuroprotection in amyotrophic lateral sclerosis

by Lydia M. Castelli, Luisa Cutillo, Cleide Dos Santos Souza, Alvaro Sanchez-Martinez, Ilaria Granata, Ya-Hui Lin, Monika A. Myszczynska, Paul R. Heath, Matthew R. Livesey, Ke Ning, Mimoun Azzouz, Pamela J. Shaw, Mario R. Guarracino, Alexander J. Whitworth, Laura Ferraiuolo, Marta Milo, Guillaume M. Hautbergue
Published 2021-08-01