Regulation of cell protrusions by small GTPases during fusion of the neural folds

by Ana Rolo, Dawn Savery, Sarah Escuin, Sandra C de Castro, Hannah EJ Armer, Peter MG Munro, Matteo A Molè, Nicholas DE Greene, Andrew J Copp
Published 2016-04-01

Pals1 prevents Rac1-dependent colorectal cancer cell metastasis by inhibiting Arf6

by Simona Mareike Lüttgenau, Christin Emming, Thomas Wagner, Julia Harms, Justine Guske, Katrin Weber, Ute Neugebauer, Rita Schröter, Olga Panichkina, Zoltán Pethő, Florian Weber, Albrecht Schwab, Anja Kathrin Wege, Pavel Nedvetsky, Michael P. Krahn
Published 2021-05-01

Integrin-Rac signalling for mammary epithelial stem cell self-renewal

by Safiah Olabi, Ahmet Ucar, Keith Brennan, Charles H. Streuli
Published 2018-10-01

Rac1 GTPase Inhibition Blocked Podocyte Injury and Glomerular Sclerosis during Hyperhomocysteinemia via Suppression of Nucleotide-Binding Oligomerization Domain-Like Receptor Conta...

by Qinghua Zhang, Sabena M. Conley, Guangbi Li, Xinxu Yuan, Pin-Lan Li
Published 2019-07-01

Rho Family of Ras-Like GTPases in Early-Branching Animals

by Silvestar Beljan, Maja Herak Bosnar, Helena Ćetković
Published 2020-10-01

Ninein is essential for apico-basal microtubule formation and CLIP-170 facilitates its redeployment to non-centrosomal microtubule organizing centres

by Deborah A. Goldspink, Chris Rookyard, Benjamin J. Tyrrell, Jonathan Gadsby, James Perkins, Elizabeth K. Lund, Niels Galjart, Paul Thomas, Tom Wileman, Mette M. Mogensen
Published 2017-01-01

Clostridioides difficile Toxin A-Induced Wnt/β-Catenin Pathway Inhibition Is Mediated by Rac1 Glucosylation

by Conceição S. Martins, Deiziane V. S. Costa, Bruno B. Lima, Renata F. C. Leitäo, Gildênio E. Freire, Guilherme F. M. Silva, Dvison M. Pacífico, José G. Abreu, Gerly A. C. Brito, Gerly A. C. Brito
Published 2020-08-01

SOX9 is a dose-dependent metastatic fate determinant in melanoma

by Xintao Yang, Rui Liang, Chunxi Liu, Jessica Aijia Liu, May Pui Lai Cheung, Xuelai Liu, On Ying Man, Xin-Yuan Guan, Hong Lok Lung, Martin Cheung
Published 2019-01-01

mTORC2/Rac1 Pathway Predisposes Cancer Aggressiveness in <i>IDH1-</i>Mutated Glioma

by Yang Liu, Yanxin Lu, Aiguo Li, Orieta Celiku, Sue Han, Mingyu Qian, Chunzhang Yang
Published 2020-03-01

Blueberry Counteracts BV-2 Microglia Morphological and Functional Switch after LPS Challenge

by Maria Giovanna De Caris, Maddalena Grieco, Elisa Maggi, Antonio Francioso, Federica Armeli, Luciana Mosca, Alessandro Pinto, Maria D’Erme, Patrizia Mancini, Rita Businaro
Published 2020-06-01

RHOG Activates RAC1 through CDC42 Leading to Tube Formation in Vascular Endothelial Cells

by Oula El Atat, Amira Fakih, Mirvat El-Sibai
Published 2019-02-01

Macropinocytosis activated by oncogenic Dbl enables specific targeted delivery of Tat/pDNA nano-complexes into ovarian cancer cells

by Niu X, Gao Z, Qi S, Su L, Yang N, Luan X, Li J, Zhang Q, An Y, Zhang S
Published 2018-08-01

Construction of an improved Aspergillus niger platform for enhanced glucoamylase secretion

by Markus R. M. Fiedler, Lars Barthel, Christin Kubisch, Corrado Nai, Vera Meyer
Published 2018-06-01

A Crucial Role for the Small GTPase Rac1 Downstream of the Protein Kinase Akt2 in Insulin Signaling that Regulates Glucose Uptake in Mouse Adipocytes

by Nobuyuki Takenaka, Mika Nakao, Sayaka Matsui, Takaya Satoh
Published 2019-10-01

Pioglitazone Confers Neuroprotection Against Ischemia-Induced Pyroptosis due to its Inhibitory Effects on HMGB-1/RAGE and Rac1/ROS Pathway by Activating PPAR-ɤ

by Pingping Xia, Yundan Pan, Fan Zhang, Na Wang, E Wang, Qulian Guo, Zhi Ye
Published 2018-03-01

Rac3 induces a molecular pathway triggering breast cancer cell aggressiveness: differences in MDA-MB-231 and MCF-7 breast cancer cell lines

by Gest Caroline, Joimel Ulrich, Huang Limin, Pritchard Linda-Louise, Petit Alexandre, Dulong Charlène, Buquet Catherine, Hu Chao-Quan, Mirshahi Pezhman, Laurent Marc, Fauvel-Lafève Françoise, Cazin Lionel, Vannier Jean-Pierre, Lu He, Soria Jeannette, Li Hong, Varin Rémi, Soria Claudine
Published 2013-02-01

Editorial on Dynamics of cAMP Signaling in Neurons: Sub-cellular Compartmentalization and Physiological Implications

by Pierre eVincent, Nicholas C Spitzer
Published 2015-08-01

Facile Preparation of Stereoblock PLA From Ring-Opening Polymerization of rac-Lactide by a Synergetic Binary Catalytic System Containing Ureas and Alkoxides

by Ze Kan, Wenlong Luo, Tong Shi, Chuanzhi Wei, Binghao Han, Dejuan Zheng, Shaofeng Liu
Published 2018-11-01

DOCK9 induces membrane ruffles and Rac1 activity in cancer HeLa epithelial cells

by Natalia Ruiz-Lafuente, Alfredo Minguela, Antonio Parrado
Published 2018-07-01

NSC23766, a Known Inhibitor of Tiam1-Rac1 Signaling Module, Prevents the Onset of Type 1 Diabetes in the NOD Mouse Model

by Rajakrishnan Veluthakal, Vaibhav Sidarala, Anjaneyulu Kowluru
Published 2016-07-01