Oximes: Inhibitors of Human Recombinant Acetylcholinesterase. A Structure-Activity Relationship (SAR) Study

by Kamil Kuca, Brian J. Bennion, Rafael Dolezal, Filip Zemek, Vendula Sepsova, Jana Zdarova Karasova, Jan Korabecny
Published 2013-08-01

Development of Thienopyridines as Potent Antiproliferative Agents

by David Barker, Lisa Ivy Pilkington, Natalie Haverkate, Euphemia Leung, Johannes Reynisson
Published 2019-08-01

Design of New Benzo[h]chromene Derivatives: Antitumor Activities and Structure-Activity Relationships of the 2,3-Positions and Fused Rings at the 2,3-Positions

by Rawda M. Okasha, Fawzia F. Alblewi, Tarek H. Afifi, Arshi Naqvi, Ahmed M. Fouda, Al-Anood M. Al-Dies, Ahmed M. El-Agrody
Published 2017-03-01

Development of Novel, Potent Phosphatidyl–Choline-Specific Phospholipase C Inhibitors

by Lisa I. Pilkington, Euphemia Leung, David Barker
Published 2019-08-01

Anti-Melanogenic Properties of Velutin and Its Analogs

by Se-Hui Jung, Hee-Young Heo, Jung-Won Choe, Jaehyun Kim, Kooyeon Lee
Published 2021-05-01

Synthesis and bioactivity of analogues of the marine antibiotic tropodithietic acid

by Patrick Rabe, Tim A. Klapschinski, Nelson L. Brock, Christian A. Citron, Paul D’Alvise, Lone Gram, Jeroen S. Dickschat
Published 2014-08-01

Facile Synthesis, Characterization and <i>in vitro</i> Antibacterial Efficacy of Functionalized 2-Substituted Benzimidazole Motifs

by Olayinka Oyewale Ajani, Olaoluwasubomi Eneyeme Joseph, King Tamunodikibugerere Iyaye, Natasha October, Damilola Victoria Aderohunmu, Shade John Olorunshola, Oluwatosin Yemisi Audu
Published 2019-12-01

PRELIMINARY STRUCTURE–ACTIVITY RELATIONSHIP STUDY OF HEPTAMETHINE INDOCYANINE DYES FOR TUMOR-TARGETED IMAGING

by QINYUAN GUO, SHENGLIN LUO, QINGRONG QI, CHUNMENG SHI
Published 2013-01-01

Synthesis and Tuberculostatic Activity Evaluation of Novel Benzazoles with Alkyl, Cycloalkyl or Pyridine Moiety

by Malwina Krause, Henryk Foks, Ewa Augustynowicz-Kopeć, Agnieszka Napiórkowska, Małgorzata Szczesio, Katarzyna Gobis
Published 2018-04-01

Design, Synthesis and Evaluation of Covalent Inhibitors for Tissue Transglutaminase and Factor XIIIa

by Akbar, Abdullah
Published 2019

Discovery of a Novel, Selective and Irreversible Inhibitor (Abivertinib) of Mutated EGFR and T790M-induced Resistance for the Treatment of NSCLC

by Long Mao, Wei Tang, Xiaoying Zhang, Jia Liu, Yile Chen, Yuning Hua, Bojie Weng, Xiaopeng Mo, Yimei Bao, Li Teng, Lijun Xu, Yuren Zhang, Jian Wu, Guanglin Zhou, Bin Liang, Changxu Xu, Biao Xi, Li Zhao, Rongda Xu, Che Fang, Wanhong Xu, Xiaobo Wang, Xiao Xu
Published 2020-06-01

<b>Bicyclic Basic Merbarone Analogues as Antiproliferative Agents</b>

by Andrea Spallarossa, Matteo Lusardi, Chiara Caneva, Aldo Profumo, Camillo Rosano, Marco Ponassi
Published 2021-01-01

Synthesis and In Vitro Antiproliferative Activity of 11-Substituted Neocryptolepines with a Branched ω-Aminoalkylamino Chain

by Elkhabiry Shaban, Marta Świtalska, Li Wang, Ning Wang, Fan Xiu, Ikuya Hayashi, Tran Anh Ngoc, Sachie Nagae, Samah El-Ghlban, Shiho Shimoda, Ahmed Abdel Aleem El Gokha, Ibrahim El Tantawy El Sayed, Joanna Wietrzyk, Tsutomu Inokuchi
Published 2017-11-01

Introducing novel potent anticancer agents of 1H-benzo[f]chromene scaffolds, targeting c-Src kinase enzyme with MDA-MB-231 cell line anti-invasion effect

by Hany E. A. Ahmed, Mohammed A. A. El-Nassag, Ahmed H. Hassan, Rawda M. Okasha, Saleh Ihmaid, Ahmed M. Fouda, Tarek H. Afifi, Ateyatallah Aljuhani, Ahmed M. El-Agrody
Published 2018-01-01

Antibacterial structure–activity relationship studies of several tricyclic sulfur-containing flavonoids

by Lucian G. Bahrin, Henning Hopf, Peter G. Jones, Laura G. Sarbu, Cornelia Babii, Alina C. Mihai, Marius Stefan, Lucian M. Birsa
Published 2016-05-01

Recent Advances in Mode of Action and Biosynthesis Studies of the Clinically Used Antibiotic Fidaxomicin

by Andrea Dorst, Erik Jung, Karl Gademann
Published 2020-04-01

&lt;em&gt;N&lt;/em&gt;-Substituted 5-Chloro-6-phenylpyridazin-3(2&lt;em&gt;H&lt;/em&gt;)-ones: Synthesis, Insecticidal Activity Against &lt;em&gt;Plutella xylostella &lt;/em&gt;(L....

by Song Yang, Qingcai Shi, Qinkun Yuan, Lijun Luo, Juan Ma, Jian Wu, Shenghong Kang
Published 2012-08-01

Synthesis, Anticancer and Antibacterial Activity of Salinomycin N-Benzyl Amides

by Michał Antoszczak, Ewa Maj, Agnieszka Napiórkowska, Joanna Stefańska, Ewa Augustynowicz-Kopeć, Joanna Wietrzyk, Jan Janczak, Bogumil Brzezinski, Adam Huczyński
Published 2014-11-01

Discovery of (5-Phenylfuran-2-yl)methanamine Derivatives as New Human Sirtuin 2 Inhibitors

by Lijiao Wang, Chao Li, Wei Chen, Chen Song, Xing Zhang, Fan Yang, Chen Wang, Yuanyuan Zhang, Shan Qian, Zhouyu Wang, Lingling Yang
Published 2019-07-01

Synthesis and Studies of the Inhibitory Effect of Hydroxylated Phenylpropanoids and Biphenols Derivatives on Tyrosinase and Laccase Enzymes

by Maria Antonietta Dettori, Davide Fabbri, Alessandro Dessì, Roberto Dallocchio, Paola Carta, Claudia Honisch, Paolo Ruzza, Donatella Farina, Rossana Migheli, Pier Andrea Serra, Roberto A. Pantaleoni, Xenia Fois, Gaia Rocchitta, Giovanna Delogu
Published 2020-06-01