Complexity and algorithms for copy-number evolution problems

by Mohammed El-Kebir, Benjamin J. Raphael, Ron Shamir, Roded Sharan, Simone Zaccaria, Meirav Zehavi, Ron Zeira
Published 2017-05-01

Cancerouspdomains: comprehensive analysis of cancer type-specific recurrent somatic mutations in proteins and domains

by Seirana Hashemi, Abbas Nowzari Dalini, Adrin Jalali, Ali Mohammad Banaei-Moghaddam, Zahra Razaghi-Moghadam
Published 2017-08-01

SCReadCounts: estimation of cell-level SNVs expression from scRNA-seq data

by N. M. Prashant, Nawaf Alomran, Yu Chen, Hongyu Liu, Pavlos Bousounis, Mercedeh Movassagh, Nathan Edwards, Anelia Horvath
Published 2021-09-01

Targeted Next-Generation Sequencing Combined With Circulating-Free DNA Deciphers Spatial Heterogeneity of Resected Multifocal Hepatocellular Carcinoma

by Jianzhen Lin, Jianzhen Lin, Songhui Zhao, Dongxu Wang, Yang Song, Yue Che, Xu Yang, Jinzhu Mao, Fucun Xie, Junyu Long, Yi Bai, Xiaobo Yang, Lei Zhang, Jin Bian, Xin Lu, Xinting Sang, Jie Pan, Kai Wang, Haitao Zhao
Published 2021-06-01

Germline and somatic mutations in the pathology of pineal cyst: A whole‐exome sequencing study of 93 individuals

by Yuanqing Yan, Rebecca Martinez, Maria N. Rasheed, Joshua Cahal, Zhen Xu, Yanning Rui, Krista J. Qualmann, John P. Hagan, Dong H. Kim
Published 2021-06-01

Immune Infiltrating Cells-Derived Risk Signature Based on Large-scale Analysis Defines Immune Landscape and Predicts Immunotherapy Responses in Glioma Tumor Microenvironment

by Nan Zhang, Nan Zhang, Hao Zhang, Zeyu Wang, Ziyu Dai, Xun Zhang, Quan Cheng, Quan Cheng, Quan Cheng, Zhixiong Liu, Zhixiong Liu
Published 2021-08-01

Does Shoot Apical Meristem Function as the Germline in Safeguarding Against Excess of Mutations?

by Agata Burian
Published 2021-08-01

Resolving rates of mutation in the brain using single-neuron genomics

by Gilad D Evrony, Eunjung Lee, Peter J Park, Christopher A Walsh
Published 2016-02-01

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

by Young Seok Ju, Ludmil B Alexandrov, Moritz Gerstung, Inigo Martincorena, Serena Nik-Zainal, Manasa Ramakrishna, Helen R Davies, Elli Papaemmanuil, Gunes Gundem, Adam Shlien, Niccolo Bolli, Sam Behjati, Patrick S Tarpey, Jyoti Nangalia, Charles E Massie, Adam P Butler, Jon W Teague, George S Vassiliou, Anthony R Green, Ming-Qing Du, Ashwin Unnikrishnan, John E Pimanda, Bin Tean Teh, Nikhil Munshi, Mel Greaves, Paresh Vyas, Adel K El-Naggar, Tom Santarius, V Peter Collins, Richard Grundy, Jack A Taylor, D Neil Hayes, David Malkin, ICGC Breast Cancer Group, ICGC Chronic Myeloid Disorders Group, ICGC Prostate Cancer Group, Christopher S Foster, Anne Y Warren, Hayley C Whitaker, Daniel Brewer, Rosalind Eeles, Colin Cooper, David Neal, Tapio Visakorpi, William B Isaacs, G Steven Bova, Adrienne M Flanagan, P Andrew Futreal, Andy G Lynch, Patrick F Chinnery, Ultan McDermott, Michael R Stratton, Peter J Campbell
Published 2014-10-01

Integrated Bioinformatical Analysis Identifies GIMAP4 as an Immune-Related Prognostic Biomarker Associated With Remodeling in Cervical Cancer Tumor Microenvironment

by Fangfang Xu, Jiacheng Shen, Shaohua Xu
Published 2021-01-01

Clonal evolution in liver cancer at single-cell and single-variant resolution

by Xianbin Su, Linan Zhao, Yi Shi, Rui Zhang, Qi Long, Shihao Bai, Qing Luo, Yingxin Lin, Xin Zou, Shila Ghazanfar, Kun Tao, Guoliang Yang, Lan Wang, Kun-Yan He, Xiaofang Cui, Jian He, Jiao-Xiang Wu, Bo Han, Bin Yan, Biao Deng, Na Wang, Xiaolin Li, Pengyi Yang, Shangwei Hou, Jielin Sun, Jean Y. H. Yang, Jinhong Chen, Ze-Guang Han
Published 2021-02-01

Frequent retrotransposition of endogenous genes in ERCC2-deficient cells derived from a patient with xeroderma pigmentosum

by Saki Aoto, Saki Katagiri, Yi Wang, Alistair T. Pagnamenta, Rie Sakamoto-Abutani, Masashi Toyoda, Akihiro Umezawa, Kohji Okamura
Published 2019-08-01

TOOme: A Novel Computational Framework to Infer Cancer Tissue-of-Origin by Integrating Both Gene Mutation and Expression

by Binsheng He, Jidong Lang, Bo Wang, Xiaojun Liu, Qingqing Lu, Jianjun He, Wei Gao, Pingping Bing, Geng Tian, Jialiang Yang
Published 2020-05-01

VariFAST: a variant filter by automated scoring based on tagged-signatures

by Hang Zhang, Ke Wang, Juan Zhou, Jianhua Chen, Yizhou Xu, Dong Wang, Xiaoqi Li, Renliang Sun, Mancang Zhang, Zhuo Wang, Yongyong Shi
Published 2019-12-01

Molecular profiling of hormone receptor-positive, HER2-negative breast cancers from patients treated with neoadjuvant endocrine therapy in the CARMINA 02 trial (UCBG-0609)

by Xu Liang, Adrien Briaux, Véronique Becette, Camille Benoist, Anais Boulai, Walid Chemlali, Anne Schnitzler, Sylvain Baulande, Sofia Rivera, Marie-Ange Mouret-Reynier, Laurence Venat Bouvet, Thibaut De La Motte Rouge, Jérôme Lemonnier, Florence Lerebours, Céline Callens
Published 2018-10-01

Differences between Well-Differentiated Neuroendocrine Tumors and Ductal Adenocarcinomas of the Pancreas Assessed by Multi-Omics Profiling

by Teresa Starzyńska, Jakub Karczmarski, Agnieszka Paziewska, Maria Kulecka, Katarzyna Kuśnierz, Natalia Żeber-Lubecka, Filip Ambrożkiewicz, Michał Mikula, Beata Kos-Kudła, Jerzy Ostrowski
Published 2020-06-01

Whole-Exome Sequencing Identifies Somatic Mutations Associated With Mortality in Metastatic Clear Cell Kidney Carcinoma

by Alejandro Mendoza-Alvarez, Beatriz Guillen-Guio, Adrian Baez-Ortega, Carolina Hernandez-Perez, Sita Lakhwani-Lakhwani, Maria-del-Carmen Maeso, Jose M. Lorenzo-Salazar, Manuel Morales, Carlos Flores, Carlos Flores, Carlos Flores, Carlos Flores
Published 2019-05-01

Genetic damage induced by CrO3 can be reduced by low doses of Protoporphyrin-IX in somatic cells of Drosophila melanogaster

by Luz M. Vidal E., Emilio Pimentel P., M. Patricia Cruces M., Juan C. Sánchez M.
Published 2014-01-01

SMAD4 Somatic Mutations in Head and Neck Carcinoma Are Associated With Tumor Progression

by Li-Han Lin, Kuo-Wei Chang, Kuo-Wei Chang, Hui-Wen Cheng, Chung-Ji Liu, Chung-Ji Liu
Published 2019-12-01