Cdk5 and GSK3β inhibit fast endophilin-mediated endocytosis

by Antonio P. A. Ferreira, Alessandra Casamento, Sara Carrillo Roas, Els F. Halff, James Panambalana, Shaan Subramaniam, Kira Schützenhofer, Laura Chan Wah Hak, Kieran McGourty, Konstantinos Thalassinos, Josef T. Kittler, Denis Martinvalet, Emmanuel Boucrot
Published 2021-04-01

Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by Asl gene transfer

by Julien Baruteau, Dany P. Perocheau, Joanna Hanley, Maëlle Lorvellec, Eridan Rocha-Ferreira, Rajvinder Karda, Joanne Ng, Natalie Suff, Juan Antinao Diaz, Ahad A. Rahim, Michael P. Hughes, Blerida Banushi, Helen Prunty, Mariya Hristova, Deborah A. Ridout, Alex Virasami, Simon Heales, Stewen J. Howe, Suzanne M. K. Buckley, Philippa B. Mills, Paul Gissen, Simon N. Waddington
Published 2018-08-01

Perceptions and experiences of healthcare workers during the COVID-19 pandemic in the UK

by Cecilia Vindrola-Padros, Samantha Vanderslott, Nehla Djellouli, Lily Andrews, Sasha Lewis-Jackson, Louisa Manby, Sam Martin, Anna Dowrick, Harrison Fillmore, Elysse Bautista Gonzalez, Lucy Mitchinson, Sophie Mulcahy Symmons, Nina Regenold, Hannah Robinson, Kirsi Sumray, Georgina Singleton, Aron Syversen, Ginger Johnson
Published 2020-11-01

Study protocol: Insight 46 – a neuroscience sub-study of the MRC National Survey of Health and Development

by Christopher A. Lane, Thomas D. Parker, Dave M. Cash, Kirsty Macpherson, Elizabeth Donnachie, Heidi Murray-Smith, Anna Barnes, Suzie Barker, Daniel G. Beasley, Jose Bras, David Brown, Ninon Burgos, Michelle Byford, M. Jorge Cardoso, Ana Carvalho, Jessica Collins, Enrico De Vita, John C. Dickson, Norah Epie, Miklos Espak, Susie M. D. Henley, Chandrashekar Hoskote, Michael Hutel, Jana Klimova, Ian B. Malone, Pawel Markiewicz, Andrew Melbourne, Marc Modat, Anette Schrag, Sachit Shah, Nikhil Sharma, Carole H. Sudre, David L. Thomas, Andrew Wong, Hui Zhang, John Hardy, Henrik Zetterberg, Sebastien Ourselin, Sebastian J. Crutch, Diana Kuh, Marcus Richards, Nick C. Fox, Jonathan M. Schott
Published 2017-04-01

Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint

by Nathalie M. Schmidt, Peter A. C. Wing, Mariana O. Diniz, Laura J. Pallett, Leo Swadling, James M. Harris, Alice R. Burton, Anna Jeffery-Smith, Nekisa Zakeri, Oliver E. Amin, Stephanie Kucykowicz, Mirjam H. Heemskerk, Brian Davidson, Tim Meyer, Joe Grove, Hans J. Stauss, Ines Pineda-Torra, Clare Jolly, Elizabeth C. Jury, Jane A. McKeating, Mala K. Maini
Published 2021-05-01

Risk factors, symptom reporting, healthcare-seeking behaviour and adherence to public health guidance: protocol for Virus Watch, a prospective community cohort study

by Pia Hardelid, Jo Gibbs, Anne M Johnson, Robert W Aldridge, Susan Michie, Alison Rodger, Richard Gilson, Tao Cheng, Andrew Hayward, Vincent Nguyen, Linda Wijlaars, Parth Patel, Thomas Byrne, Eleni Nastouli, Sarah Beale, Madhumita Shrotri, Ellen Fragaszy, Jana Kovar, Anna Aryee, Wing Lam Erica Fong, Cyril Geismar, Annalan M D Navaratnam, Moira Spyer, Ben Killingley, Ingemar Cox, Vasileios Lampos, Rachel A McKendry, Yunzhe Liu
Published 2021-06-01

LARP7 family proteins have conserved function in telomerase assembly

by Laura C. Collopy, Tracy L. Ware, Tomas Goncalves, Sunnvør í Kongsstovu, Qian Yang, Hanna Amelina, Corinne Pinder, Ala Alenazi, Vera Moiseeva, Siân R. Pearson, Christine A. Armstrong, Kazunori Tomita
Published 2018-02-01

Author Correction: Mir142 loss unlocks IDH2R140-dependent leukemogenesis through antagonistic regulation of HOX genes

by A. Marshall, J. Kasturiarachchi, P. Datta, Y. Guo, E. Deltcheva, C. James, J. Brown, G. May, N. Anandagoda, I. Jackson, J. K. Howard, E. Ghazaly, S. Brooks, A. Khwaja, M. Araki, K. Araki, D. Linch, G. M. Lord, T. Enver, R. Nimmo
Published 2021-03-01

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

by Alexandra L Young, Razvan V Marinescu, Neil P Oxtoby, Martina Bocchetta, Keir Yong, Nicholas C Firth, David M Cash, David L Thomas, Katrina M Dick, Jorge Cardoso, John van Swieten, Barbara Borroni, Daniela Galimberti, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Caroline Graff, Fabrizio Tagliavini, Giovanni B Frisoni, Robert Laforce, Elizabeth Finger, Alexandre de Mendonça, Sandro Sorbi, Jason D Warren, Sebastian Crutch, Nick C Fox, Sebastien Ourselin, Jonathan M Schott, Jonathan D Rohrer, Daniel C Alexander, The Genetic FTD Initiative (GENFI), The Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Published 2018-10-01

Miro clusters regulate ER-mitochondria contact sites and link cristae organization to the mitochondrial transport machinery

by Souvik Modi, Guillermo López-Doménech, Elise F. Halff, Christian Covill-Cooke, Davor Ivankovic, Daniela Melandri, I. Lorena Arancibia-Cárcamo, Jemima J. Burden, Alan R. Lowe, Josef T. Kittler
Published 2019-09-01

Similarities and Differences Between Juvenile and Adult Spondyloarthropathies

by Corinne Fisher, Corinne Fisher, Corinne Fisher, Coziana Ciurtin, Coziana Ciurtin, Coziana Ciurtin, Maria Leandro, Maria Leandro, Maria Leandro, Debajit Sen, Debajit Sen, Debajit Sen, Lucy R. Wedderburn, Lucy R. Wedderburn, Lucy R. Wedderburn
Published 2021-05-01

Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma

by Giulia Agliardi, Anna Rita Liuzzi, Alastair Hotblack, Donatella De Feo, Nicolás Núñez, Cassandra L. Stowe, Ekaterina Friebel, Francesco Nannini, Lukas Rindlisbacher, Thomas A. Roberts, Rajiv Ramasawmy, Iwan P. Williams, Bernard M. Siow, Mark F. Lythgoe, Tammy L. Kalber, Sergio A. Quezada, Martin A. Pule, Sonia Tugues, Karin Straathof, Burkhard Becher
Published 2021-01-01

A population‐based study of head injury, cognitive function and pathological markers

by Sarah‐Naomi James, Jennifer M. Nicholas, Christopher A. Lane, Thomas D. Parker, Kirsty Lu, Ashvini Keshavan, Sarah M. Buchanan, Sarah E. Keuss, Heidi Murray‐Smith, Andrew Wong, David M. Cash, Ian B. Malone, Josephine Barnes, Carole H. Sudre, William Coath, Lloyd Prosser, Sebastien Ourselin, Marc Modat, David L. Thomas, Jorge Cardoso, Amanda Heslegrave, Henrik Zetterberg, Sebastian J. Crutch, Jonathan M. Schott, Marcus Richards, Nick C. Fox
Published 2021-04-01

Higher cost of finance exacerbates a climate investment trap in developing economies

by Nadia Ameli, Olivier Dessens, Matthew Winning, Jennifer Cronin, Hugues Chenet, Paul Drummond, Alvaro Calzadilla, Gabrial Anandarajah, Michael Grubb
Published 2021-06-01

Origin of High-Efficiency Photoelectrochemical Water Splitting on Hematite/Functional Nanohybrid Metal Oxide Overlayer Photoanode after a Low Temperature Inert Gas Annealing Treatm...

by SocMan Ho-Kimura, Benjamin A. D. Williamson, Sanjayan Sathasivam, Savio J. A. Moniz, Guanjie He, Wenjun Luo, David O. Scanlon, Junwang Tang, Ivan P. Parkin
Published 2019-01-01

A systematic review of the clinical effectiveness and cost-effectiveness of sensory, psychological and behavioural interventions for managing agitation in older adults with dementi...

by Gill Livingston, Lynsey Kelly, Elanor Lewis-Holmes, Gianluca Baio, Stephen Morris, Nishma Patel, Rumana Z Omar, Cornelius Katona, Claudia Cooper
Published 2014-06-01

SHOC2 phosphatase-dependent RAF dimerization mediates resistance to MEK inhibition in RAS-mutant cancers

by Greg G. Jones, Isabel Boned del Río, Sibel Sari, Aysen Sekerim, Lucy C. Young, Nicole Hartig, Itziar Areso Zubiaur, Mona A. El-Bahrawy, Rob E. Hynds, Winnie Lei, Miriam Molina-Arcas, Julian Downward, Pablo Rodriguez-Viciana
Published 2019-06-01

28 Trusting who knows best when managing long-term conditions in dementia: Findings from a qualitative study of stakeholder perspectives

by C Cooper, J Rees, A Burton, K Walters, M Leverton, P Rapaport, R Herat-Gunaratne, J Beresford-Dent
Published 2021-03-01

A distal regulatory region of a class I human histone deacetylase

by Nicolas D. Werbeck, Vaibhav Kumar Shukla, Micha B. A. Kunze, Havva Yalinca, Ruth B. Pritchard, Lucas Siemons, Somnath Mondal, Simon O. R. Greenwood, John Kirkpatrick, Charles M. Marson, D. Flemming Hansen
Published 2020-07-01

Two forms of death in ageing Caenorhabditis elegans

by Yuan Zhao, Ann F. Gilliat, Matthias Ziehm, Mark Turmaine, Hongyuan Wang, Marina Ezcurra, Chenhao Yang, George Phillips, David McBay, William B. Zhang, Linda Partridge, Zachary Pincus, David Gems
Published 2017-05-01