HIV-Specific CD8+ T Cells Exhibit Reduced and Differentially Regulated Cytolytic Activity in Lymphoid Tissue

by Morgan A. Reuter, Perla M. Del Rio Estrada, Marcus Buggert, Constantinos Petrovas, Sara Ferrando-Martinez, Son Nguyen, Alberto Sada Japp, Yuria Ablanedo-Terrazas, Amaranta Rivero-Arrieta, Leticia Kuri-Cervantes, Heidi M. Gunzelman, Emma Gostick, David A. Price, Richard A. Koup, Ali Naji, David H. Canaday, Gustavo Reyes-Terán, Michael R. Betts
Published 2017-12-01

Fusion peptide priming reduces immune responses to HIV-1 envelope trimer base

by Angela R. Corrigan, Hongying Duan, Cheng Cheng, Christopher A. Gonelli, Li Ou, Kai Xu, Megan E. DeMouth, Hui Geng, Sandeep Narpala, Sarah O’Connell, Baoshan Zhang, Tongqing Zhou, Manjula Basappa, Jeffrey C. Boyington, Steven J. Chen, Sijy O’Dell, Amarendra Pegu, Tyler Stephens, Yaroslav Tsybovsky, Jelle van Schooten, John P. Todd, Shuishu Wang, Nicole A. Doria-Rose, Kathryn E. Foulds, Richard A. Koup, Adrian B. McDermott, Marit J. van Gils, Peter D. Kwong, John R. Mascola
Published 2021-04-01

Editorial: Lymph Node T Cell Dynamics and Novel Strategies for HIV Cure

by Constantinos Petrovas, Vijayakumar Velu
Published 2018-12-01

Immunomodulation Induced by Host Pathogen Interaction

by Hadi M. Yassine, Syed M. Moin, Farhan S. Cyprian, Adam K. Wheatley, Gheyath K. Nasrallah
Published 2019-01-01

Influenza Vaccine With Consensus Internal Antigens as Immunogens Provides Cross-Group Protection Against Influenza A Viruses

by Xinci Xie, Chen Zhao, Qian He, Tianyi Qiu, Songhua Yuan, Longfei Ding, Lu Liu, Lang Jiang, Jing Wang, Linxia Zhang, Chao Zhang, Xiang Wang, Dongming Zhou, Xiaoyan Zhang, Jianqing Xu
Published 2019-07-01

B Cell-Based Vaccine Transduced With ESAT6-Expressing Vaccinia Virus and Presenting α-Galactosylceramide Is a Novel Vaccine Candidate Against ESAT6-Expressing Mycobacterial Disease...

by Bo-Eun Kwon, Jae-Hee Ahn, Eun-Kyoung Park, Hyunjin Jeong, Hyo-Ji Lee, Yu-Jin Jung, Sung Jae Shin, Hye-Sook Jeong, Jung Sik Yoo, EunKyoung Shin, Sang-Gu Yeo, Sun-Young Chang, Hyun-Jeong Ko
Published 2019-10-01

A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage

by Chao Shan, Antonio E. Muruato, Brett W. Jagger, Justin Richner, Bruno T. D. Nunes, Daniele B. A. Medeiros, Xuping Xie, Jannyce G. C. Nunes, Kaitlyn M. Morabito, Wing-Pui Kong, Theodore C. Pierson, Alan D. Barrett, Scott C. Weaver, Shannan L. Rossi, Pedro F. C. Vasconcelos, Barney S. Graham, Michael S. Diamond, Pei-Yong Shi
Published 2017-09-01

Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization

by Siyang Sun, Ye Xiang, Wataru Akahata, Heather Holdaway, Pankaj Pal, Xinzheng Zhang, Michael S Diamond, Gary J Nabel, Michael G Rossmann
Published 2013-04-01

Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens

by George Ueda, Aleksandar Antanasijevic, Jorge A Fallas, William Sheffler, Jeffrey Copps, Daniel Ellis, Geoffrey B Hutchinson, Adam Moyer, Anila Yasmeen, Yaroslav Tsybovsky, Young-Jun Park, Matthew J Bick, Banumathi Sankaran, Rebecca A Gillespie, Philip JM Brouwer, Peter H Zwart, David Veesler, Masaru Kanekiyo, Barney S Graham, Rogier W Sanders, John P Moore, Per Johan Klasse, Andrew B Ward, Neil P King, David Baker
Published 2020-08-01

Microbial Translocation and Infectious Diseases: What Is the Link?

by Gabriella D'Ettorre, Daniel Douek, Mirko Paiardini, Giancarlo Ceccarelli, Vincenzo Vullo
Published 2012-01-01

Myeloid Cells Enriched for a Dendritic Cell Population From People Living With HIV Have Altered Gene Expression Not Restored by Antiretroviral Therapy

by Shannon M. Murray, Yuwei Zhang, Daniel C. Douek, Rafick P. Sekaly
Published 2020-03-01

Hemagglutinin-targeting Artificial MicroRNAs Expressed by Adenovirus Protect Mice From Different Clades of H5N1 Infection

by Xinying Tang, Hongbo Zhang, Yufeng Song, Dongming Zhou, Jieru Wang
Published 2016-01-01

A deadly dance: the choreography of host–pathogen interactions, as revealed by single-cell technologies

by Pratip K. Chattopadhyay, Mario Roederer, Diane L. Bolton
Published 2018-11-01

Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity

by Mariya B. Shapiro, Tracy Cheever, Delphine C. Malherbe, Shilpi Pandey, Jason Reed, Eun Sung Yang, Keyun Wang, Amarendra Pegu, Xuejun Chen, Don Siess, David Burke, Heidi Henderson, Rebecca Lewinsohn, Miranda Fischer, Jeffrey J. Stanton, Michael K. Axthelm, Christoph Kahl, Byung Park, Anne D. Lewis, Jonah B. Sacha, John R. Mascola, Ann J. Hessell, Nancy L. Haigwood
Published 2020-01-01

HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations

by Xiaochu Ma, Maolin Lu, Jason Gorman, Daniel S Terry, Xinyu Hong, Zhou Zhou, Hong Zhao, Roger B Altman, James Arthos, Scott C Blanchard, Peter D Kwong, James B Munro, Walther Mothes
Published 2018-03-01

cAb-Rep: A Database of Curated Antibody Repertoires for Exploring Antibody Diversity and Predicting Antibody Prevalence

by Yicheng Guo, Kevin Chen, Peter D. Kwong, Peter D. Kwong, Lawrence Shapiro, Lawrence Shapiro, Lawrence Shapiro, Zizhang Sheng
Published 2019-10-01

HIV proviruses with identical sequences arise from cell expansion and infection by a common ancestor virus

by S. Patro, A. Niyongabo, S. Guo, X. Wu, E. Boritz, S. Deeks, F. Maldarelli, S. Hughes, J. Coffin, M. Kearney
Published 2019-12-01

Endothelial Targeted Strategies to Combat Oxidative Stress: Improving Outcomes in Traumatic Brain Injury

by Evan M. Lutton, S. Katie Farney, Allison M. Andrews, Allison M. Andrews, Vladimir V. Shuvaev, Gwo-Yu Chuang, Vladimir R. Muzykantov, Servio H. Ramirez, Servio H. Ramirez, Servio H. Ramirez
Published 2019-06-01

Plasmodium 18S rRNA of intravenously administered sporozoites does not persist in peripheral blood

by Sean C. Murphy, Andrew S. Ishizuka, Zachary P. Billman, Tayla M. Olsen, Annette M. Seilie, Ming Chang, Nahum Smith, Vorada Chuenchob, Sumana Chakravarty, B. Kim Lee Sim, Stefan H. I. Kappe, Stephen L. Hoffman, Robert A. Seder
Published 2018-07-01

Monocytes Acquire the Ability to Prime Tissue-Resident T Cells via IL-10-Mediated TGF-β Release

by Elizabeth A. Thompson, Patricia A. Darrah, Kathryn E. Foulds, Elena Hoffer, Alayna Caffrey-Carr, Sophie Norenstedt, Leif Perbeck, Robert A. Seder, Ross M. Kedl, Karin Loré
Published 2019-07-01