antiviral activity 26 nonhuman 20 human 19 Article 16 Humans 16 controlled study 15 SARS-CoV-2 14 COVID-19 13 chemistry 13 unclassified drug 13 Antiviral Agents 12 Severe acute respiratory syndrome coronavirus 2 12 antivirus agent 12 drug effect 10 virus replication 10 drug therapy 9 coronavirus disease 2019 8 molecular docking 7 Antiviral activity 6 Molecular Dynamics Simulation 6 binding affinity 6 computer model 6 human cell 6 in vitro study 6 molecular dynamics 6 IC50 5 Pandemics 5 animal cell 5 binding site 5 drug efficacy 5