Quantitative analyses reveal extracellular dynamics of Wnt ligands in Xenopus embryos

by Yusuke Mii, Kenichi Nakazato, Chan-Gi Pack, Takafumi Ikeda, Yasushi Sako, Atsushi Mochizuki, Masanori Taira, Shinji Takada
Published 2021-04-01

Corollary discharge promotes a sustained motor state in a neural circuit for navigation

by Ni Ji, Vivek Venkatachalam, Hillary Denise Rodgers, Wesley Hung, Taizo Kawano, Christopher M Clark, Maria Lim, Mark J Alkema, Mei Zhen, Aravinthan DT Samuel
Published 2021-04-01

Two opposite voltage-dependent currents control the unusual early development pattern of embryonic Renshaw cell electrical activity

by Juliette Boeri, Claude Meunier, Hervé Le Corronc, Pascal Branchereau, Yulia Timofeeva, François-Xavier Lejeune, Christine Mouffle, Hervé Arulkandarajah, Jean Marie Mangin, Pascal Legendre, Antonny Czarnecki
Published 2021-04-01

NHR-49/PPAR-α and HLH-30/TFEB cooperate for C. elegans host defense via a flavin-containing monooxygenase

by Khursheed A Wani, Debanjan Goswamy, Stefan Taubert, Ramesh Ratnappan, Arjumand Ghazi, Javier E Irazoqui
Published 2021-05-01

Likelihood approximation networks (LANs) for fast inference of simulation models in cognitive neuroscience

by Alexander Fengler, Lakshmi N Govindarajan, Tony Chen, Michael J Frank
Published 2021-04-01

ZC3H4 restricts non-coding transcription in human cells

by Chris Estell, Lee Davidson, Pieter C Steketee, Adam Monier, Steven West
Published 2021-04-01

Simple biochemical features underlie transcriptional activation domain diversity and dynamic, fuzzy binding to Mediator

by Adrian L Sanborn, Benjamin T Yeh, Jordan T Feigerle, Cynthia V Hao, Raphael JL Townshend, Erez Lieberman Aiden, Ron O Dror, Roger D Kornberg
Published 2021-04-01

Multiplexed mRNA assembly into ribonucleoprotein particles plays an operon-like role in the control of yeast cell physiology

by Rohini R Nair, Dmitry Zabezhinsky, Rita Gelin-Licht, Brian J Haas, Michael CA Dyhr, Hannah S Sperber, Chad Nusbaum, Jeffrey E Gerst
Published 2021-05-01

DRAXIN regulates interhemispheric fissure remodelling to influence the extent of corpus callosum formation

by Laura Morcom, Timothy J Edwards, Eric Rider, Dorothy Jones-Davis, Jonathan WC Lim, Kok-Siong Chen, Ryan J Dean, Jens Bunt, Yunan Ye, Ilan Gobius, Rodrigo Suárez, Simone Mandelstam, Elliott H Sherr, Linda J Richards
Published 2021-05-01

Cell-scale biophysical determinants of cell competition in epithelia

by Daniel Gradeci, Anna Bove, Giulia Vallardi, Alan R Lowe, Shiladitya Banerjee, Guillaume Charras
Published 2021-05-01

Metabolic flexibility via mitochondrial BCAA carrier SLC25A44 is required for optimal fever

by Takeshi Yoneshiro, Naoya Kataoka, Jacquelyn M Walejko, Kenji Ikeda, Zachary Brown, Momoko Yoneshiro, Scott B Crown, Tsuyoshi Osawa, Juro Sakai, Robert W McGarrah, Phillip J White, Kazuhiro Nakamura, Shingo Kajimura
Published 2021-05-01

Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics

by Juana Serrano-Lopez, Shailaja Hegde, Sachin Kumar, Josefina Serrano, Jing Fang, Ashley M Wellendorf, Paul A Roche, Yamileth Rangel, Leolene J Carrington, Hartmut Geiger, H Leighton Grimes, Sanjiv Luther, Ivan Maillard, Joaquin Sanchez-Garcia, Daniel T Starczynowski, Jose A Cancelas
Published 2021-04-01

Non-canonical Hedgehog signaling regulates spinal cord and muscle regeneration in Xenopus laevis larvae

by Andrew M Hamilton, Olga A Balashova, Laura N Borodinsky
Published 2021-05-01

Endogenous p53 expression in human and mouse is not regulated by its 3′UTR

by Sibylle Mitschka, Christine Mayr
Published 2021-05-01

Mapping the endemicity and seasonality of clinical malaria for intervention targeting in Haiti using routine case data

by Ewan Cameron, Alyssa J Young, Katherine A Twohig, Emilie Pothin, Darlene Bhavnani, Amber Dismer, Jean Baptiste Merilien, Karen Hamre, Phoebe Meyer, Arnaud Le Menach, Justin M Cohen, Samson Marseille, Jean Frantz Lemoine, Marc-Aurèle Telfort, Michelle A Chang, Kimberly Won, Alaine Knipes, Eric Rogier, Punam Amratia, Daniel J Weiss, Peter W Gething, Katherine E Battle
Published 2021-06-01

Integrated sensing of host stresses by inhibition of a cytoplasmic two-component system controls M. tuberculosis acute lung infection

by John A Buglino, Gaurav D Sankhe, Nathaniel Lazar, James M Bean, Michael S Glickman
Published 2021-05-01

Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist

by Caleb R Glassman, Leon Su, Sonia S Majri-Morrison, Hauke Winkelmann, Fei Mo, Peng Li, Magdiel Pérez-Cruz, Peggy P Ho, Ievgen Koliesnik, Nadine Nagy, Tereza Hnizdilova, Lora K Picton, Marek Kovar, Paul Bollyky, Lawrence Steinman, Everett Meyer, Jacob Piehler, Warren J Leonard, K Christopher Garcia
Published 2021-05-01

Danger zone

by Zohra Butt, Ian Prior
Published 2021-05-01

Signaling levels mold the RAS mutation tropism of urethane

by Siqi Li, Christopher M Counter
Published 2021-05-01

Toxoplasma TgATG9 is critical for autophagy and long-term persistence in tissue cysts

by David Smith, Geetha Kannan, Isabelle Coppens, Fengrong Wang, Hoa Mai Nguyen, Aude Cerutti, Einar B Olafsson, Patrick A Rimple, Tracey L Schultz, Nayanna M Mercado Soto, Manlio Di Cristina, Sébastien Besteiro, Vern B Carruthers
Published 2021-04-01