enzyme inhibition 54 Article 49 controlled study 45 unclassified drug 40 nonhuman 34 human 24 IC50 22 Humans 19 chemistry 19 metabolism 18 drug synthesis 15 plant extract 15 enzyme activity 14 molecular docking 14 drug effect 13 male 12 proton nuclear magnetic resonance 12 drug structure 11 acetylcholinesterase 10 alpha glucosidase 9 antioxidant 9 antioxidant activity 9 human cell 9 in vitro study 9 plant leaf 9 quercetin 9 Acetylcholinesterase 8 Animals 8 Enzyme inhibition 8 animal cell 8