Search Results - "glucosylceramide synthase"

1

The effects of rosmarinic acid and carnosic acid on cell viability and ceramide metabolism in the HEP-G2 cells

by Narges Najjarpour, Masoud Mashadi Akbar Boujar
Published 2016-06-01

Subjects: “...glucosylceramide synthase...”

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2

GCS overexpression is associated with multidrug resistance of human HCT-8 colon cancer cells

by Song Min, Zang Weidong, Zhang Baohua, Cao Jing, Yang Guanrui
Published 2012-03-01

Subjects: “...Glucosylceramide synthase...”

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3

PS Dependent APP Cleavage Regulates Glucosylceramide Synthase and is Affected in Alzheimer's Disease

by Marcus O.W. Grimm, Benjamin Hundsdörfer, Sven Grösgen, Janine Mett, Valerie C. Zimmer, Christoph P. Stahlmann, Viola J. Haupenthal, Tatjana L. Rothhaar, Johannes Lehmann, Andreas Pätzold, Eva G. Zinser, Heikki Tanila, Jie Shen, Ulrike Müller, Heike S. Grimm, Tobias Hartmann
Published 2014-06-01

Subjects: “...Glucosylceramide synthase...”

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4

The Tricyclodecan-9-yl-xanthogenate D609 Triggers Ceramide Increase and Enhances FasL-Induced Caspase-Dependent and -Independent Cell Death in T Lymphocytes

by Bruno Ségui, Thierry Levade, Hervé Benoist, Delphine Milhas, Nathalie Andrieu-Abadie
Published 2012-07-01

Subjects: “...glucosylceramide synthase...”

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5

Regulation of sphingolipid and glycosphingolipid metabolism in extrahepatic tissues by endotoxin

by Riaz A. Memon, Walter M. Holleran, Yoshikazu Uchida, Arthur H. Moser, Carl Grunfeld, Kenneth R. Feingold
Published 2001-03-01

Subjects: “...glucosylceramide synthase...”

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6

Glucosylceramide Synthase Is Involved in Development of Invariant Natural Killer T Cells

by Zoran V. Popovic, Zoran V. Popovic, Mariona Rabionet, Richard Jennemann, Damir Krunic, Roger Sandhoff, Hermann-Josef Gröne, Stefan Porubsky
Published 2017-07-01

Subjects: “...glucosylceramide synthase...”

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7

The effect of the glucosylceramide synthase inhibitor lucerastat on cardiac repolarization: results from a thorough QT study in healthy subjects

by Markus S. Mueller, Patricia N. Sidharta, Christine Voors-Pette, Borje Darpo, Hongqi Xue, Jasper Dingemanse
Published 2020-10-01

Subjects: “...Glucosylceramide synthase inhibitor...”

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8

4-IBP, a σ1 Receptor Agonist, Decreases the Migration of Human Cancer Cells, Including Glioblastoma Cells, In Vitro and Sensitizes Them In Vitro and In Vivo to Cytotoxic Insults of...

by Veronique Mégalizzi, Véronique Mathieu, Tatjana Mijatovic, Philippe Gailly, Olivier Debeir, Nancy De Neve, Marc Van Damme, Gianluca Bontempi, Benjamin Haibe-Kains, Christine Decaestecker, Yasuko Kondo, Robert Kiss, Florence Lefranc
Published 2007-05-01

Subjects: “...glucosylceramide synthase...”

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9

Glucosylceramide synthase regulates hepatocyte repair after concanavalin A-induced immune-mediated liver injury

by Jian Gan, Qin Gao, Li Li Wang, Ai Ping Tian, Long Dong Zhu, Li Ting Zhang, Wei Zhou, Xiao Rong Mao, Jun Feng Li
Published 2021-09-01

Subjects: “...Glucosylceramide synthase...”

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10

A novel glucosylceramide synthase inhibitor attenuates alpha synuclein pathology and lysosomal dysfunction in preclinical models of synucleinopathy

by Mali Cosden, Sarah Jinn, Lihang Yao, Cheryl A. Gretzula, Monika Kandebo, Dawn Toolan, Nathan G. Hatcher, Lei Ma, Wei Lemaire, Gregory C. Adam, Christine Burlein, Christina Minnick, Rose Flick, Marla L. Watt, James Mulhearn, Mark Fraley, Robert E. Drolet, Jacob N. Marcus, Sean M. Smith
Published 2021-11-01

Subjects: “...Glucosylceramide synthase inhibitor...”

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11

Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism[S]

by Thomas D. Mullen, Stefka Spassieva, Russell W. Jenkins, Kazuyuki Kitatani, Jacek Bielawski, Yusuf A. Hannun, Lina M. Obeid
Published 2011-01-01

Subjects: “...glucosylceramide synthase...”

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12

Selective Targeting of the Interconversion between Glucosylceramide and Ceramide by Scaffold Tailoring of Iminosugar Inhibitors

by Cécile Baudoin-Dehoux, Tessa Castellan, Frédéric Rodriguez, Arnaud Rives, Fabien Stauffert, Virginie Garcia, Thierry Levade, Philippe Compain, Yves Génisson
Published 2019-01-01

Subjects: “...glucosylceramide synthase inhibitors...”

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13

Gangliosides do not affect ABC transporter function in human neuroblastoma cells

by Anne-Jan Dijkhuis, Karin Klappe, Willem Kamps, Hannie Sietsma, Jan Willem Kok
Published 2006-06-01

Subjects: “...glucosylceramide synthase...”

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14

Production of gangliosidebiosynthetic membrane enzymes for biochemical and functionalstudies : Expression, purification and crystallizationoptimization of Thermococcus onnurineus D...

by Lindholm, Ellinor
Published 2018

Subjects: “...glucosylceramide synthase...”

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15

Novel Intrinsic and Extrinsic Approaches to Selectively Regulate Glycosphingolipid Metabolism

by Kamani, Mustafa
Published 2013

Subjects: “...Glucosylceramide synthase...”

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16

Novel Intrinsic and Extrinsic Approaches to Selectively Regulate Glycosphingolipid Metabolism

by Kamani, Mustafa
Published 2013

Subjects: “...Glucosylceramide synthase...”

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17

Safety, Pharmacokinetics, and Pharmacodynamics of Oral Venglustat in Patients with Parkinson's Disease and a GBA Mutation: Results from Part 1 of the Randomized, Double-Blinded, Pl...

by Alcalay, R.N, Cutter, G., Fischer, T.Z, Gaemers, S.J.M, Gasser, T., Giladi, N., Hatano, T., Hattori, N., Höglinger, G.U, Isaacson, S.H, Marek, K., Minini, P., Peterschmitt, M.J, Saiki, H., Sardi, S.P, Saubadu, S., Schapira, A.H.V, Scherzer, C.R, Sharma, J., Simuni, T., Walbillic, S.
Published 2022

Subjects: “...glucosylceramide synthase (GCS) inhibition...”

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