Synergism between the phosphatidylinositol 3-kinase p110β isoform inhibitor AZD6482 and the mixed lineage kinase 3 inhibitor URMC-099 on the blockade of glioblastoma cell motility...

by Hua-fu Zhao, Chang-peng Wu, Xiu-ming Zhou, Peng-yu Diao, Yan-wen Xu, Jing Liu, Jing Wang, Xian-jian Huang, Wen-lan Liu, Zhong-ping Chen, Guo-dong Huang, Wei-ping Li
Published 2021-01-01

Combined targeting of G protein‐coupled receptor and EGF receptor signaling overcomes resistance to PI3K pathway inhibitors in PTEN‐null triple negative breast cancer

by Davide Zecchin, Christopher Moore, Fanourios Michailidis, Stuart Horswell, Sareena Rana, Michael Howell, Julian Downward
Published 2020-08-01

Oleic Acid Protects Against Insulin Resistance by Regulating the Genes Related to the PI3K Signaling Pathway

by Carlos López-Gómez, Concepción Santiago-Fernández, Sara García-Serrano, Eva García-Escobar, Carolina Gutiérrez-Repiso, Cristina Rodríguez-Díaz, Ailec Ho-Plágaro, Flores Martín-Reyes, Lourdes Garrido-Sánchez, Sergio Valdés, Alberto Rodríguez-Cañete, Francisca Rodríguez-Pacheco, Eduardo García-Fuentes
Published 2020-08-01

CRKL Mediates p110β-Dependent PI3K Signaling in PTEN-Deficient Cancer Cells

by Jing Zhang, Xueliang Gao, Fabienne Schmit, Guillaume Adelmant, Michael J. Eck, Jarrod A. Marto, Jean J. Zhao, Thomas M. Roberts
Published 2017-07-01

Class I Phosphoinositide 3-Kinase <i>PIK3CA</i>/p110α and <i>PIK3CB</i>/p110β Isoforms in Endometrial Cancer

by Fatemeh Mazloumi Gavgani, Victoria Smith Arnesen, Rhîan G. Jacobsen, Camilla Krakstad, Erling A. Hoivik, Aurélia E. Lewis
Published 2018-12-01