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  1. 21
    The Pituitary Gland is a Novel Major Site of Action of Metformin in Non-Human Primates: a Potential Path to Expand and Integrate Its Metabolic Actions
    Subjects: “...Phenformin...”
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    Article
  2. 22
    Metabolic Profiles Associated With Metformin Efficacy in Cancer
    Subjects: “...phenformin...”
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  3. 23
    The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in <i>KRAS</i>-Driven Lung Cancer
    “... phenformin in <i>Aldh1l1</i><sup>−/−</sup>; <i>Kras<sup>LA2</sup></i> mice dramatically decreased the number...”
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    Article
  4. 24
    Graphene-based phenformin carriers for cancer cell treatment: a comparative study between oxidized and pegylated pristine graphene in human cells and zebrafish†
    Subjects: “...Phenformin...”
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  5. 25
    Statistically controlled identification of differentially expressed genes in one-to-one cell line comparisons of the CMAP database for drug repositioning
    Subjects: “...Phenformin...”
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  6. 26
    Effects of Metformin on Spontaneous Ca<sup>2+</sup> Signals in Cultured Microglia Cells under Normoxic and Hypoxic Conditions
    Subjects: “...phenformin...”
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    Article
  7. 27
    Phenformin Induces Cell Cycle Change, Apoptosis, and Mesenchymal-Epithelial Transition and Regulates the AMPK/mTOR/p70s6k and MAPK/ERK Pathways in Breast Cancer Cells.
    “... phenformin was reported to potentially be a more active anti-cancer agent than metformin. However, little...”
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  8. 28
    Antidiabetic Biguanides Radiosensitize Hypoxic Colorectal Cancer Cells Through a Decrease in Oxygen Consumption
    Subjects: “...phenformin...”
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    Article
  9. 29
    Enhanced Sensitivity of Nonsmall Cell Lung Cancer with Acquired Resistance to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors to Phenformin: The Roles of a Metabolic Shift to Oxidative Phosphorylation and Redox Balance
    “... of cell proliferation and energy metabolism, respectively. In vivo anticancer effect of phenformin...”
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    Article
  10. 30
    Reply to Krupenko et al. Comment on “Lee et al. The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer <em>Cancers</em> 2020, <em>12</em>, 1382”
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    Article
  11. 31
    Is ALDH1L1 Elevated in Lung Cancer? Comment on: Lee, S.-H.; et al. “The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer” <i>Cancers</i> 2020, <i>12</i>, 1382
    by Sergey A. Krupenko, Jaspreet Sharma
    Published 2021-04-01
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    Article
  12. 32
    Studies on the mechanism of action of Wy 23675, a novel hypoglycaemic agent
    by Myles, David D.
    Published 1980
    “... with that of the sulphonylurea, tolbutamide, and that of the biguanide, phenformin. Wy 23675 has been shown, like tolbutamide...”
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  13. 33
    AMPK Signaling Involvement for the Repression of the IL-1β-Induced Group IIA Secretory Phospholipase A2 Expression in VSMCs.
    “...), especially during atherogenesis. Phenformin, a biguanide family member, by its anti-inflammatory properties...”
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    Article
  14. 34
    Optimization of biguanide derivatives as selective antitumor agents blocking adaptive stress responses in the tumor microenvironment
    by Narise K, Okuda K, Enomoto Y, Hirayama T, Nagasawa H
    Published 2014-06-01
    “... and synthesized on the basis of the arylmethylbiguanide scaffold of phenformin, were used in structure activity...”
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    Article
  15. 35
    Pharmacological AMP kinase activators target the nucleolar organization and control cell proliferation.
    “...<h4>Aims</h4>Phenformin, resveratrol and AICAR stimulate the energy sensor 5'-AMP activated kinase...”
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    Article
  16. 36
    Combinatorial Therapeutic Effect of Inhibitors of Aldehyde Dehydrogenase and Mitochondrial Complex I, and the Chemotherapeutic Drug, Temozolomide against Glioblastoma Tumorspheres
    “..., and phenformin, a biguanide compound that depletes oxidative phosphorylation, with the chemotherapeutic drug...”
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    Article
  17. 37
    Defining the short-term effects of pharmacological 5′-AMP activated kinase modulators on mitochondrial polarization, morphology and heterogeneity
    “.... Specifically, we evaluated the effects of pharmacological AMPK modulators (compound C, AICAR, phenformin...”
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    Article
  18. 38
    The effect of metformin on vascular function and AMP-activated protein kinase activation in Type 2 diabetes
    by Boyle, James Graham
    Published 2009
    “... and adipose AMPK activity. The effects of metformin, its closely related analogue phenformin and rosiglitazone...”
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  19. 39
    Screening of virtual libraries for monoamine oxidase inhibitors / Melinda Barkhuizen
    by Barkhuizen, Melinda
    Published 2014
    “...) and phenformin (IC50 = 41 μM for MAO-A) were selected for further analysis. An examination of the recoveries...”
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  20. 40
    Screening of virtual libraries for monoamine oxidase inhibitors / Melinda Barkhuizen
    by Barkhuizen, Melinda
    Published 2014
    “...) and phenformin (IC50 = 41 μM for MAO-A) were selected for further analysis. An examination of the recoveries...”
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