Effect of tirapazamine on selected kidney parameters in rats treated with cisplatin

by Sysa Marcin, Pawlowski Kamil, Slabczynski Piotr, Burdan Franciszek, Dudka Jaroslaw
Published 2019-03-01

Time-Resolved Spectroscopic Studies of the Photochemistry of riboflavin, aromatic N-Oxides and the absolute reactivity of hydroxyl radical

by Shi, Xiaofeng
Published 2005

Kinetics of Flavoenzyme-Catalyzed Reduction of Tirapazamine Derivatives: Implications for Their Prooxidant Cytotoxicity

by Aušra Nemeikaitė-Čėnienė, Jonas Šarlauskas, Violeta Jonušienė, Audronė Marozienė, Lina Misevičienė, Aliaksei V. Yantsevich, Narimantas Čėnas
Published 2019-09-01

DNA Damage Measured by the Comet Assay in Head and Neck Cancer Patients Treated with Tirapazamine

by Mary Jo Dorie, Mary S. Kovacs, Edward C. Gabalski, Markus Adam, Quynh-T Le, Daniel A. Bloch, Harlan A. Pinto, David J. Terris, J. Martin Brown
Published 1999-11-01

New tirapazamine derivatives protect cardiomyocytes from doxorubicin toxicity

by Korga Agnieszka, Iwan Magdalena, Matosiuk Dariusz, Rzadkowska Marzena, Szacon Elzbieta, Humeniuk Ewelina, Sysa Marcin, Ostrowska Marta, Dudka Jaroslaw
Published 2020-03-01

Computational Studies of Anti-Tumor Drug Tirapazamine and Reactions and Rearrangements of nitrenes and Carbenes

by Liu, Jin
Published 2005

Ring-Selective Fragmentation in the Tirapazamine Molecule upon Low-Energy Electron Attachment

by Eugene Arthur-Baidoo, Joao Ameixa, Milan Ončák, Stephan Denifl
Published 2021-03-01

Aerobic Cytotoxicity of Aromatic <i>N-</i>Oxides: The Role of NAD(P)H:Quinone Oxidoreductase (NQO1)

by Aušra Nemeikaitė-Čėnienė, Jonas Šarlauskas, Lina Misevičienė, Audronė Marozienė, Violeta Jonušienė, Mindaugas Lesanavičius, Narimantas Čėnas
Published 2020-11-01

Targeting Hypoxia: Hypoxia-Activated Prodrugs in Cancer Therapy

by Yue Li, Yue Li, Yue Li, Long Zhao, Long Zhao, Xiao-Feng Li, Xiao-Feng Li
Published 2021-07-01

Combinational phototherapy and hypoxia-activated chemotherapy favoring antitumor immune responses

by Ma B, Sheng J, Wang P, Jiang Z, Borrathybay E
Published 2019-06-01

DFT STUDY ON THE MECHANISTIC, ENERGETIC AND STRUCTURAL ASPECTS OF ADSORPTION OF TIRAPAZAMINE ONTO PRISTINE AND FUNCTIONALIZED CARBON NANOTUBES

by Sadaf Avarand, Ali Morsali, Mohammad M. Heravi, S. Ali Beyramabadi

Reductive Metabolism Influences the Toxicity and Pharmacokinetics of the Hypoxia-Targeted Benzotriazine Di-Oxide Anticancer Agent SN30000 in Mice

by Yongchuan Gu, Tony T.-A. Chang, Jingli Wang, Jagdish K. Jaiswal, David Edwards, Noel J. Downes, H. D. Sarath Liyanage, Courtney R. H. Lynch, Frederik B. Pruijn, Anthony J. R. Hickey, Michael P. Hay, William R. Wilson, Kevin O. Hicks
Published 2017-08-01

Subcellular Location of Tirapazamine Reduction Dramatically Affects Aerobic but Not Anoxic Cytotoxicity

by Chris P. Guise, Maria R. Abbattista, Robert F. Anderson, Dan Li, Rana Taghipouran, Angela Tsai, Su Jung Lee, Jeff B. Smaill, William A. Denny, Michael P. Hay, William R. Wilson, Kevin O. Hicks, Adam V. Patterson
Published 2020-10-01

Development of [131I]I-EOE-TPZ and [131I]I-EOE-TPZMO: Novel Tirapazamine (TPZ)-Based Radioiodinated Pharmaceuticals for Application in Theranostic Management of Hypoxia

by Hassan Elsaidi, Fatemeh Ahmadi, Leonard I. Wiebe, Piyush Kumar
Published 2019-01-01

Preliminary Investigation of the Antibacterial Activity of Antitumor Drug 3-Amino-1,2,4-Benzotriazine-1,4-Dioxide (Tirapazamine) and its Derivatives

by Evelina Polmickaitė-Smirnova, Jonas Šarlauskas, Kastis Krikštopaitis, Živilė Lukšienė, Zita Staniulytė, Žilvinas Anusevičius
Published 2020-06-01

Benzotriazine Di-Oxide Prodrugs for Exploiting Hypoxia and Low Extracellular pH in Tumors

by Michael P. Hay, Hong Nam Shin, Way Wua Wong, Wan Wan Sahimi, Aaron T.D. Vaz, Pooja Yadav, Robert F. Anderson, Kevin O. Hicks, William R. Wilson
Published 2019-07-01