Lipids and ions traverse the membrane by the same physical pathway in the nhTMEM16 scramblase

by Tao Jiang, Kuai Yu, H Criss Hartzell, Emad Tajkhorshid
Published 2017-09-01

Mitochondrial VDAC1: A Key Gatekeeper as Potential Therapeutic Target

by Amadou K. S. Camara, Amadou K. S. Camara, YiFan Zhou, Po-Chao Wen, Emad Tajkhorshid, Wai-Meng Kwok, Wai-Meng Kwok, Wai-Meng Kwok
Published 2017-06-01

Aquaporin-7: A Dynamic Aquaglyceroporin With Greater Water and Glycerol Permeability Than Its Bacterial Homolog GlpF

by Fraser J. Moss, Paween Mahinthichaichan, David T. Lodowski, David T. Lodowski, Thomas Kowatz, Emad Tajkhorshid, Andreas Engel, Walter F. Boron, Walter F. Boron, Walter F. Boron, Ardeschir Vahedi-Faridi
Published 2020-06-01

Structural basis of complex formation between mitochondrial anion channel VDAC1 and Hexokinase-II

by Nandan Haloi, Po-Chao Wen, Qunli Cheng, Meiying Yang, Gayathri Natarajan, Amadou K. S. Camara, Wai-Meng Kwok, Emad Tajkhorshid
Published 2021-06-01

Revealing an outward-facing open conformational state in a CLC Cl–/H+ exchange transporter

by Chandra M Khantwal, Sherwin J Abraham, Wei Han, Tao Jiang, Tanmay S Chavan, Ricky C Cheng, Shelley M Elvington, Corey W Liu, Irimpan I Mathews, Richard A Stein, Hassane S Mchaourab, Emad Tajkhorshid, Merritt Maduke
Published 2016-01-01

Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter

by Smriti Mishra, Brandy Verhalen, Richard A Stein, Po-Chao Wen, Emad Tajkhorshid, Hassane S Mchaourab
Published 2014-05-01

A CLC-ec1 mutant reveals global conformational change and suggests a unifying mechanism for the CLC Cl–/H+ transport cycle

by Tanmay S Chavan, Ricky C Cheng, Tao Jiang, Irimpan I Mathews, Richard A Stein, Antoine Koehl, Hassane S Mchaourab, Emad Tajkhorshid, Merritt Maduke
Published 2020-04-01

Structural basis for the reaction cycle of DASS dicarboxylate transporters

by David B Sauer, Noah Trebesch, Jennifer J Marden, Nicolette Cocco, Jinmei Song, Akiko Koide, Shohei Koide, Emad Tajkhorshid, Da-Neng Wang
Published 2020-09-01

Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation

by Sean W Fanning, Christopher G Mayne, Venkatasubramanian Dharmarajan, Kathryn E Carlson, Teresa A Martin, Scott J Novick, Weiyi Toy, Bradley Green, Srinivas Panchamukhi, Benita S Katzenellenbogen, Emad Tajkhorshid, Patrick R Griffin, Yang Shen, Sarat Chandarlapaty, John A Katzenellenbogen, Geoffrey L Greene
Published 2016-02-01

Aβ(1-42) tetramer and octamer structures reveal edge conductivity pores as a mechanism for membrane damage

by Sonia Ciudad, Eduard Puig, Thomas Botzanowski, Moeen Meigooni, Andres S. Arango, Jimmy Do, Maxim Mayzel, Mariam Bayoumi, Stéphane Chaignepain, Giovanni Maglia, Sarah Cianferani, Vladislav Orekhov, Emad Tajkhorshid, Benjamin Bardiaux, Natàlia Carulla
Published 2020-06-01

Direct protein-lipid interactions shape the conformational landscape of secondary transporters

by Chloe Martens, Mrinal Shekhar, Antoni J. Borysik, Andy M. Lau, Eamonn Reading, Emad Tajkhorshid, Paula J. Booth, Argyris Politis
Published 2018-10-01