Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody

by Shahir S. Rizk, Somnath Mukherjee, Akiko Koide, Shohei Koide, Anthony A. Kossiakoff
Published 2017-04-01

ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation

by Nataliya Nady, Ankit Gupta, Ziyang Ma, Tomek Swigut, Akiko Koide, Shohei Koide, Joanna Wysocka
Published 2015-11-01

Structural basis for the reaction cycle of DASS dicarboxylate transporters

by David B Sauer, Noah Trebesch, Jennifer J Marden, Nicolette Cocco, Jinmei Song, Akiko Koide, Shohei Koide, Emad Tajkhorshid, Da-Neng Wang
Published 2020-09-01

The structural basis of promiscuity in small multidrug resistance transporters

by Ali A. Kermani, Christian B. Macdonald, Olive E. Burata, B. Ben Koff, Akiko Koide, Eric Denbaum, Shohei Koide, Randy B. Stockbridge
Published 2020-11-01

T cell receptor-like recognition of tumor in vivo by synthetic antibody fragment.

by Keith R Miller, Akiko Koide, Brenda Leung, Jonathan Fitzsimmons, Bryan Yoder, Hong Yuan, Michael Jay, Sachdev S Sidhu, Shohei Koide, Edward J Collins
Published 2012-01-01

Selective inhibition of STAT3 signaling using monobodies targeting the coiled-coil and N-terminal domains

by Grégory La Sala, Camille Michiels, Tim Kükenshöner, Tania Brandstoetter, Barbara Maurer, Akiko Koide, Kelvin Lau, Florence Pojer, Shohei Koide, Veronika Sexl, Laure Dumoutier, Oliver Hantschel
Published 2020-08-01

Selective and noncovalent targeting of RAS mutants for inhibition and degradation

by Kai Wen Teng, Steven T. Tsai, Takamitsu Hattori, Carmine Fedele, Akiko Koide, Chao Yang, Xuben Hou, Yingkai Zhang, Benjamin G. Neel, John P. O’Bryan, Shohei Koide
Published 2021-05-01

Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase

by Sina Reckel, Charlotte Gehin, Delphine Tardivon, Sandrine Georgeon, Tim Kükenshöner, Frank Löhr, Akiko Koide, Lena Buchner, Alejandro Panjkovich, Aline Reynaud, Sara Pinho, Barbara Gerig, Dmitri Svergun, Florence Pojer, Peter Güntert, Volker Dötsch, Shohei Koide, Anne-Claude Gavin, Oliver Hantschel
Published 2017-12-01

Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins.

by Nan Zhong, Peter Loppnau, Alma Seitova, Mani Ravichandran, Maria Fenner, Harshika Jain, Anandi Bhattacharya, Ashley Hutchinson, Marcin Paduch, Vincent Lu, Michal Olszewski, Anthony A Kossiakoff, Evan Dowdell, Akiko Koide, Shohei Koide, Haiming Huang, Vincent Nadeem, Sachdev S Sidhu, Jack F Greenblatt, Edyta Marcon, Cheryl H Arrowsmith, Aled M Edwards, Susanne Gräslund
Published 2015-01-01

Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis

by Sarah E. Garnish, Yanxiang Meng, Akiko Koide, Jarrod J. Sandow, Eric Denbaum, Annette V. Jacobsen, Wayland Yeung, Andre L. Samson, Christopher R. Horne, Cheree Fitzgibbon, Samuel N. Young, Phoebe P. C. Smith, Andrew I. Webb, Emma J. Petrie, Joanne M. Hildebrand, Natarajan Kannan, Peter E. Czabotar, Shohei Koide, James M. Murphy
Published 2021-04-01

Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme

by Zhening Zhang, Wenguang G Liang, Lucas J Bailey, Yong Zi Tan, Hui Wei, Andrew Wang, Mara Farcasanu, Virgil A Woods, Lauren A McCord, David Lee, Weifeng Shang, Rebecca Deprez-Poulain, Benoit Deprez, David R Liu, Akiko Koide, Shohei Koide, Anthony A Kossiakoff, Sheng Li, Bridget Carragher, Clinton S Potter, Wei-Jen Tang
Published 2018-03-01

Antibody isotype diversity against SARS-CoV-2 is associated with differential serum neutralization capacities

by Maria G. Noval, Maria E. Kaczmarek, Akiko Koide, Bruno A. Rodriguez-Rodriguez, Ping Louie, Takuya Tada, Takamitsu Hattori, Tatyana Panchenko, Larizbeth A. Romero, Kai Wen Teng, Andrew Bazley, Maren de Vries, Marie I. Samanovic, Jeffrey N. Weiser, Ioannis Aifantis, Joan Cangiarella, Mark J. Mulligan, Ludovic Desvignes, Meike Dittmann, Nathaniel R. Landau, Maria Aguero-Rosenfeld, Shohei Koide, Kenneth A. Stapleford
Published 2021-03-01