Prevention of cytotoxic T cell escape using a heteroclitic subdominant viral T cell determinant.

by Noah S Butler, Alex Theodossis, Andrew I Webb, Roza Nastovska, Sri Harsha Ramarathinam, Michelle A Dunstone, Jamie Rossjohn, Anthony W Purcell, Stanley Perlman
Published 2008-10-01

Aspartyl Protease 5 Matures Dense Granule Proteins That Reside at the Host-Parasite Interface in Toxoplasma gondii

by Michael J. Coffey, Laura F. Dagley, Simona Seizova, Eugene A. Kapp, Giuseppe Infusini, David S. Roos, Justin A. Boddey, Andrew I. Webb, Christopher J. Tonkin
Published 2018-10-01

High yield production of a soluble human interleukin-3 variant from E. coli with wild-type bioactivity and improved radiolabeling properties.

by Timothy R Hercus, Emma F Barry, Mara Dottore, Barbara J McClure, Andrew I Webb, Angel F Lopez, Ian G Young, James M Murphy
Published 2013-01-01

Enrichment of extracellular vesicles from human synovial fluid using size exclusion chromatography

by Andrew D. Foers, Simon Chatfield, Laura F. Dagley, Benjamin J. Scicluna, Andrew I. Webb, Lesley Cheng, Andrew F. Hill, Ian P. Wicks, Ken C. Pang
Published 2018-12-01

BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association

by Michael A. Dengler, Adeline Y. Robin, Leonie Gibson, Mark X. Li, Jarrod J. Sandow, Sweta Iyer, Andrew I. Webb, Dana Westphal, Grant Dewson, Jerry M. Adams
Published 2019-04-01

Elucidating the mitochondrial proteome of Toxoplasma gondii reveals the presence of a divergent cytochrome c oxidase

by Azadeh Seidi, Linden S Muellner-Wong, Esther Rajendran, Edwin T Tjhin, Laura F Dagley, Vincent YT Aw, Pierre Faou, Andrew I Webb, Christopher J Tonkin, Giel G van Dooren
Published 2018-09-01

Arrdc4‐dependent extracellular vesicle biogenesis is required for sperm maturation

by Natalie J. Foot, Macarena B. Gonzalez, Kelly Gembus, Pamali Fonseka, Jarrod J. Sandow, Thuy Tien Nguyen, Diana Tran, Andrew I. Webb, Suresh Mathivanan, Rebecca L. Robker, Sharad Kumar
Published 2021-06-01

Suppressor of Cytokine Signaling (SOCS) 5 utilises distinct domains for regulation of JAK1 and interaction with the adaptor protein Shc-1.

by Edmond M Linossi, Indu R Chandrashekaran, Tatiana B Kolesnik, James M Murphy, Andrew I Webb, Tracy A Willson, Lukasz Kedzierski, Alex N Bullock, Jeffrey J Babon, Raymond S Norton, Nicos A Nicola, Sandra E Nicholson
Published 2013-01-01

Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix

by Michael R. Oliver, Christopher R. Horne, Safal Shrestha, Jeremy R. Keown, Lung-Yu Liang, Samuel N. Young, Jarrod J. Sandow, Andrew I. Webb, David C. Goldstone, Isabelle S. Lucet, Natarajan Kannan, Peter Metcalf, James M. Murphy
Published 2021-02-01

The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation

by Swarna L. Vijayaraj, Rebecca Feltham, Maryam Rashidi, Daniel Frank, Zhengyang Liu, Daniel S. Simpson, Gregor Ebert, Angelina Vince, Marco J. Herold, Andrew Kueh, Jaclyn S. Pearson, Laura F. Dagley, James M. Murphy, Andrew I. Webb, Kate E. Lawlor, James E. Vince
Published 2021-05-01

Protein kinase A negatively regulates Ca2+ signalling in Toxoplasma gondii.

by Alessandro D Uboldi, Mary-Louise Wilde, Emi A McRae, Rebecca J Stewart, Laura F Dagley, Luning Yang, Nicholas J Katris, Sanduni V Hapuarachchi, Michael J Coffey, Adele M Lehane, Cyrille Y Botte, Ross F Waller, Andrew I Webb, Malcolm J McConville, Christopher J Tonkin
Published 2018-09-01

Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis

by Sarah E. Garnish, Yanxiang Meng, Akiko Koide, Jarrod J. Sandow, Eric Denbaum, Annette V. Jacobsen, Wayland Yeung, Andre L. Samson, Christopher R. Horne, Cheree Fitzgibbon, Samuel N. Young, Phoebe P. C. Smith, Andrew I. Webb, Emma J. Petrie, Joanne M. Hildebrand, Natarajan Kannan, Peter E. Czabotar, Shohei Koide, James M. Murphy
Published 2021-04-01

Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3

by Emma J. Petrie, Jarrod J. Sandow, Wil I.L. Lehmann, Lung-Yu Liang, Diane Coursier, Samuel N. Young, Wilhelmus J.A. Kersten, Cheree Fitzgibbon, André L. Samson, Annette V. Jacobsen, Kym N. Lowes, Amanda E. Au, Hélène Jousset Sabroux, Najoua Lalaoui, Andrew I. Webb, Guillaume Lessene, Gerard Manning, Isabelle S. Lucet, James M. Murphy
Published 2019-09-01

Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis

by Emma J. Petrie, Jarrod J. Sandow, Annette V. Jacobsen, Brian J. Smith, Michael D. W. Griffin, Isabelle S. Lucet, Weiwen Dai, Samuel N. Young, Maria C. Tanzer, Ahmad Wardak, Lung-Yu Liang, Angus D. Cowan, Joanne M. Hildebrand, Wilhelmus J. A. Kersten, Guillaume Lessene, John Silke, Peter E. Czabotar, Andrew I. Webb, James M. Murphy
Published 2018-06-01

Cytotoxic T cells swarm by homotypic chemokine signalling

by Jorge Luis Galeano Niño, Sophie V Pageon, Szun S Tay, Feyza Colakoglu, Daryan Kempe, Jack Hywood, Jessica K Mazalo, James Cremasco, Matt A Govendir, Laura F Dagley, Kenneth Hsu, Simone Rizzetto, Jerzy Zieba, Gregory Rice, Victoria Prior, Geraldine M O'Neill, Richard J Williams, David R Nisbet, Belinda Kramer, Andrew I Webb, Fabio Luciani, Mark N Read, Maté Biro
Published 2020-10-01