Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues

by Katherine A. Davies, Cheree Fitzgibbon, Samuel N. Young, Sarah E. Garnish, Wayland Yeung, Diane Coursier, Richard W. Birkinshaw, Jarrod J. Sandow, Wil I. L. Lehmann, Lung-Yu Liang, Isabelle S. Lucet, James D. Chalmers, Wayne M. Patrick, Natarajan Kannan, Emma J. Petrie, Peter E. Czabotar, James M. Murphy
Published 2020-06-01

Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3

by Emma J. Petrie, Jarrod J. Sandow, Wil I.L. Lehmann, Lung-Yu Liang, Diane Coursier, Samuel N. Young, Wilhelmus J.A. Kersten, Cheree Fitzgibbon, André L. Samson, Annette V. Jacobsen, Kym N. Lowes, Amanda E. Au, Hélène Jousset Sabroux, Najoua Lalaoui, Andrew I. Webb, Guillaume Lessene, Gerard Manning, Isabelle S. Lucet, James M. Murphy
Published 2019-09-01