Networks Inferred from Biochemical Data Reveal Profound Differences in Toll-like Receptor and Inflammatory Signaling between Normal and Transformed Hepatocytes

by Alexopoulos, Leonidas G., Rodriguez, Julio Saez, Cosgrove, Benjamin D., Lauffenburger, Douglas A., Sorger, Peter K.
Published 2013

Engineered Bivalent Ligands to Bias ErbB Receptor-mediated Signaling and Phenotypes

by Jay, Steven M., Kurtagic, Elma, Alvarez, Luis M., De Picciotto, Seymour, Hawkins, Jessica F., Prince, Robin N., Guerrero, Yadir, Treasure, Carolyn L., Lee, Richard T., Griffith, Linda G., Sanchez, Edgar
Published 2012

Mechanistic basis for the evolution of chalcone synthase catalytic cysteine reactivity in land plants

by Liou, Geoffrey, Chiang, Ying-Chih, Wang, Yi, Weng, Jing-Ke
Published 2020

The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond

by Fedeles, Bogdan I., Singh, Vipender, Delaney, James C., Li, Deyu, Essigmann, John M.
Published 2015

The E2 Ubiquitin-conjugating Enzyme UBE2J1 Is Required for Spermiogenesis in Mice

by Koenig, Paul-Albert, Hagiwara, Masatoshi, Maruyama, Takeshi, Watson, Nicki, Page, David C, Nicholls, Peter, Schmidt, Florian Ingo, Ploegh, Hidde, Frydman, Galit H.
Published 2017

Replication origin-flanking roadblocks reveal origin-licensing dynamics and altered sequence dependence

by Warner, Megan Dobbins, Azmi, Ishara F, Kang, Sukhyun, Bell, Stephen P
Published 2020

Structural Basis of Rev1-mediated Assembly of a Quaternary Vertebrate Translesion Polymerase Complex Consisting of Rev1, Heterodimeric Polymerase (Pol) κ, and Pol ζ

by Wojtaszek, Jessica, Lee, Chul-Jin, D'Souza, Sanjay Victor, Minesinger, Brenda, Kim, Hyungjin, D'Andrea, Alan D., Walker, Graham C., Zhou, Pei
Published 2014

SPASM and Twitch Domains in S-Adenosylmethionine (SAM) Radical Enzymes

by Goldman, Peter J., Grell, Tsehai Ariane, Drennan, Catherine L
Published 2015

Strong Enrichment of Aromatic Residues in Binding Sites from a Charge-neutralized Hyperthermostable Sso7d Scaffold Library

by Lobner, Elisabeth, Traxlmayr, Michael, Kiefer, Jonathan, Srinivas, Raja Ram, Tisdale, Alison W., Mehta, Naveen, Yang, Nicole Jie Yeon, Tidor, Bruce, Wittrup, Karl Dane
Published 2017

Chemical genetics analysis of an aniline mustard anticancer agent reveals complex I of the electron transport chain as a target

by Fedeles, Bogdan I., Zhu, Angela W., Young, Kellie S., Hillier, Shawn M., Proffitt, Kyle D., Essigmann, John M., Croy, Robert G.
Published 2012

Expanding the Repertoire of Amyloid Polymorphs by Co-polymerization of Related Protein Precursors

by Sarell, Claire J., Woods, Lucy A., Su, Yongchao, Debelouchina, Galia Tzvetanova, Ashcroft, Alison E, Griffin, Robert Guy, Stockley, Peter G., Radford, Sheena E.
Published 2013

Noncanonical Role of the PDZ4 Domain of the Adaptor Protein PDZK1 in the Regulation of the Hepatic High Density Lipoprotein Receptor Scavenger Receptor Class B, Type I (SR-BI)

by Tsukamoto, Kosuke, Wales, Thomas E., Daniels, Kathleen, Pal, Rinku, Sheng, Ren, Cho, Wonhwa, Stafford, Walter, Engen, John R., Krieger, Monty, Kocher, Olivier
Published 2014

Vascular Endothelial Growth Factor (VEGF) and Platelet (PF-4) Factor 4 Inputs Modulate Human Microvascular Endothelial Signaling in a Three-Dimensional Matrix Migration Context

by Hang, Ta-Chun, Tedford, Nathan C., Reddy, Raven J., Rimchala, Tharathorn, Wells, Alan, White, Forest M., Kamm, Roger Dale, Lauffenburger, Douglas A.
Published 2014

Bacterial N-Glycosylation Efficiency is Dependent on the Structural Context of Target Sequons

by Silverman, Julie, Imperiali, Barbara
Published 2018

Protonation equilibria and pore-opening structure of the dual-histidine influenza B virus M2 transmembrane proton channel from solid-state NMR

by Wang, Jun, Williams, Jonathan Kyle, Shcherbakov, Alexander Aleksandrovich, Hong, Mei
Published 2018

Matrilin-1 Is an Inhibitor of Neovascularization

by Foradori, Matthew J., Harper, Jay, Li, Xin, Tsang, Paul C. W., Moses, Marsha A., Chen, Qian, Fernandez, Cecilia A, Langer, Robert S
Published 2018

Mitochondrial methionyl N-formylation affects steady-state levels of oxidative phosphorylation complexes and their organization into supercomplexes

by Arguello, Tania, Köhrer, Caroline, RajBhandary, Uttam L., Moraes, Carlos T.
Published 2020

Angiogenin activates the astrocytic Nrf2/antioxidant-response element pathway and thereby protects murine neurons from oxidative stress

by Hoang, Trish T., Johnson, Delinda A., Raines, Ronald T, Johnson, Jeffrey A.
Published 2020

Synthetic biology strategies for improving microbial synthesis of "green" biopolymers

by Anderson, Lisa A, Islam, M. Ahsanul, Prather, Kristala L
Published 2020

The Clustered, Regularly Interspaced, Short Palindromic Repeats-associated Endonuclease 9 (CRISPR/Cas9)-created

by Duan, Yajian, Ma, Gaoen, Huang, Xionggao, D'Amore, Patricia A., Zhang, Feng, Lei, Hetian
Published 2018