Structures of Foot-and-mouth Disease Virus with neutralizing antibodies derived from recovered natural host reveal a mechanism for cross-serotype neutralization.

by Yong He, Kun Li, Yimei Cao, Zixian Sun, Pinghua Li, Huifang Bao, Sheng Wang, Guoqiang Zhu, Xingwen Bai, Pu Sun, Xuerong Liu, Cheng Yang, Zaixin Liu, Zengjun Lu, Zihe Rao, Zhiyong Lou
Published 2021-04-01

Climate change and the emergence of fungal pathogens.

by Nnaemeka Emmanuel Nnadi, Dee A Carter
Published 2021-04-01

RhoGTPases and inflammasomes: Guardians of effector-triggered immunity.

by Océane Dufies, Laurent Boyer
Published 2021-04-01

The antiviral sirtuin 3 bridges protein acetylation to mitochondrial integrity and metabolism during human cytomegalovirus infection.

by Xinlei Sheng, Ileana M Cristea
Published 2021-04-01

Mechanisms of HIV-1 evasion to the antiviral activity of chemokine CXCL12 indicate potential links with pathogenesis.

by Marie Armani-Tourret, Zhicheng Zhou, Romain Gasser, Isabelle Staropoli, Vincent Cantaloube-Ferrieu, Yann Benureau, Javier Garcia-Perez, Mayte Pérez-Olmeda, Valérie Lorin, Bénédicte Puissant-Lubrano, Lambert Assoumou, Constance Delaugerre, Jean-Daniel Lelièvre, Yves Lévy, Hugo Mouquet, Guillaume Martin-Blondel, Jose Alcami, Fernando Arenzana-Seisdedos, Jacques Izopet, Philippe Colin, Bernard Lagane
Published 2021-04-01

RNA thermosensors facilitate Streptococcus pneumoniae and Haemophilus influenzae immune evasion.

by Hannes Eichner, Jens Karlsson, Laura Spelmink, Anuj Pathak, Lok-To Sham, Birgitta Henriques-Normark, Edmund Loh
Published 2021-04-01

Human plasmacytoid dendritic cells at the crossroad of type I interferon-regulated B cell differentiation and antiviral response to tick-borne encephalitis virus.

by Marilena P Etna, Aurora Signorazzi, Daniela Ricci, Martina Severa, Fabiana Rizzo, Elena Giacomini, Andrea Gaggioli, Isabelle Bekeredjian-Ding, Anke Huckriede, Eliana M Coccia
Published 2021-04-01

Toward understanding microbiota homeostasis in the plant kingdom.

by Bradley C Paasch, Sheng Yang He
Published 2021-04-01

Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection.

by Wanhai Qin, Xanthe Brands, Cornelis Van't Veer, Alex F de Vos, Jean-Claude Sirard, Joris J T H Roelofs, Brendon P Scicluna, Tom van der Poll
Published 2021-04-01

Mutations that confer resistance to broadly-neutralizing antibodies define HIV-1 variants of transmitting mothers from that of non-transmitting mothers.

by Amit Kumar, Elena E Giorgi, Joshua J Tu, David R Martinez, Joshua Eudailey, Michael Mengual, Manukumar Honnayakanahalli Marichannegowda, Russell Van Dyke, Feng Gao, Sallie R Permar
Published 2021-04-01

FOXO regulates the expression of antimicrobial peptides and promotes phagocytosis of hemocytes in shrimp antibacterial immunity.

by Cang Li, Pan-Pan Hong, Ming-Chong Yang, Xiao-Fan Zhao, Jin-Xing Wang
Published 2021-04-01

Hepatitis C virus infection restricts human LINE-1 retrotransposition in hepatoma cells.

by Anja Schöbel, Van Nguyen-Dinh, Gerald G Schumann, Eva Herker
Published 2021-04-01

Effector and regulator: Diverse functions of C. elegans C-type lectin-like domain proteins.

by Barbara Pees, Wentao Yang, Anke Kloock, Carola Petersen, Lena Peters, Li Fan, Meike Friedrichsen, Sabrina Butze, Alejandra Zárate-Potes, Hinrich Schulenburg, Katja Dierking
Published 2021-04-01

Lipocalin 2 modulates dendritic cell activity and shapes immunity to influenza in a microbiome dependent manner.

by Martin L Watzenboeck, Barbara Drobits, Sophie Zahalka, Anna-Dorothea Gorki, Asma Farhat, Federica Quattrone, Anastasiya Hladik, Karin Lakovits, Gabriel M Richard, Therese Lederer, Birgit Strobl, Gijs A Versteeg, Louis Boon, Philipp Starkl, Sylvia Knapp
Published 2021-04-01

Genome-wide association study of signature genetic alterations among pseudomonas aeruginosa cystic fibrosis isolates.

by Wontae Hwang, Ji Hyun Yong, Kyung Bae Min, Kang-Mu Lee, Ben Pascoe, Samuel K Sheppard, Sang Sun Yoon
Published 2021-06-01

Using Plasmodium knowlesi as a model for screening Plasmodium vivax blood-stage malaria vaccine targets reveals new candidates.

by Duncan N Ndegwa, Prasun Kundu, Jessica B Hostetler, Alejandro Marin-Menendez, Theo Sanderson, Kioko Mwikali, Lisa H Verzier, Rachael Coyle, Sophie Adjalley, Julian C Rayner
Published 2021-07-01

Neuraminidase-associated plasminogen recruitment enables systemic spread of natural avian Influenza viruses H3N1.

by Jacob Schön, Angele Breithaupt, Dirk Höper, Jacqueline King, Anne Pohlmann, Rokshana Parvin, Klaus-Peter Behr, Bernd-Andreas Schwarz, Martin Beer, Jürgen Stech, Timm Harder, Christian Grund
Published 2021-04-01

DNA damage and oxidative stress in human cells infected by Trypanosoma cruzi.

by Pilar T V Florentino, Davi Mendes, Francisca Nathalia L Vitorino, Davi J Martins, Julia P C Cunha, Renato A Mortara, Carlos F M Menck
Published 2021-04-01

The larger attachment glycoprotein of respiratory syncytial virus produced in primary human bronchial epithelial cultures reduces infectivity for cell lines.

by Tiffany King, Asuncion Mejias, Octavio Ramilo, Mark E Peeples
Published 2021-04-01

The role of antimicrobial peptides in the evolution of endosymbiotic protein import.

by Oliver D Caspari, Ingrid Lafontaine
Published 2021-04-01