Search Results - Christopher M Sassetti
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New TB treatments hiding in plain sight by Andrew J Olive, Christopher M Sassetti
Published in EMBO Molecular Medicine (2014-12-01)Get full text
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Genome-wide screen of Mycobacterium tuberculosis-infected macrophages revealed GID/CTLH complex-mediated modulation of bacterial growth by Nelson V. Simwela, Luana Johnston, Paulina Pavinski Bitar, Eleni Jaecklein, Craig Altier, Christopher M. Sassetti, David G. Russell
Published in Nature Communications (2024-10-01)Get full text
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Cross-species transcriptomics translation reveals a role for the unfolded protein response in Mycobacterium tuberculosis infection by Krista M. Pullen, Ryan Finethy, Seung-Hyun B. Ko, Charlotte J. Reames, Christopher M. Sassetti, Douglas A. Lauffenburger
Published in npj Systems Biology and Applications (2025-02-01)Get full text
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The Rip1 intramembrane protease contributes to iron and zinc homeostasis in Mycobacterium tuberculosis by Samantha J. Nelson, John T. Williams, John A. Buglino, Subhalaxmi Nambi, Lisa J. Lojek, Michael S. Glickman, Thomas R. Ioerger, Christopher M. Sassetti
Published in mSphere (2023-08-01)Get full text
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Glycerol contributes to tuberculosis susceptibility in male mice with type 2 diabetes by Nuria Martinez, Lorissa J. Smulan, Michael L. Jameson, Clare M. Smith, Kelly Cavallo, Michelle Bellerose, John Williams, Kim West, Christopher M. Sassetti, Amit Singhal, Hardy Kornfeld
Published in Nature Communications (2023-09-01)Get full text
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A cytoplasmic peptidoglycan amidase homologue controls mycobacterial cell wall synthesis by Cara C Boutte, Christina E Baer, Kadamba Papavinasasundaram, Weiru Liu, Michael R Chase, Xavier Meniche, Sarah M Fortune, Christopher M Sassetti, Thomas R Ioerger, Eric J Rubin
Published in eLife (2016-06-01)Get full text
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Frequently arising ESX-1-associated phase variants influence Mycobacterium tuberculosis fitness in the presence of host and antibiotic pressures by Michael J. Luna, Peter O. Oluoch, Jiazheng Miao, Peter Culviner, Kadamba Papavinasasundaram, Eleni Jaecklein, Scarlet S. Shell, Thomas R. Ioerger, Sarah M. Fortune, Maha R. Farhat, Christopher M. Sassetti
Published in mBio (2025-03-01)Get full text
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Multiple genetic loci influence vaccine-induced protection against Mycobacterium tuberculosis in genetically diverse mice. by Sherry L Kurtz, Richard E Baker, Frederick J Boehm, Chelsea C Lehman, Lara R Mittereder, Hamda Khan, Amy P Rossi, Daniel M Gatti, Gillian Beamer, Christopher M Sassetti, Karen L Elkins
Published in PLoS Pathogens (2024-03-01)Get full text
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Host genetic background is a barrier to broadly effective vaccine–mediated protection against tuberculosis by Rocky Lai, Diana N. Gong, Travis Williams, Abiola F. Ogunsola, Kelly Cavallo, Cecilia S. Lindestam Arlehamn, Sarah Acolatse, Gillian L. Beamer, Martin T. Ferris, Christopher M. Sassetti, Douglas A. Lauffenburger, Samuel M. Behar
Published in The Journal of Clinical Investigation (2023-07-01)Get full text
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Differentiating the roles of Mycobacterium tuberculosis substrate binding proteins, FecB and FecB2, in iron uptake. by Rodger de Miranda, Bonnie J Cuthbert, Thaís Klevorn, Alex Chao, Jessica Mendoza, Mark Arbing, Paul J Sieminski, Kadamba Papavinasasundaram, Sumer Abdul-Hafiz, Sum Chan, Christopher M Sassetti, Sabine Ehrt, Celia W Goulding
Published in PLoS Pathogens (2023-09-01)Get full text
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