Search Results - Frauke Christ

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  1. 1

    Towards a Functional Cure of HIV-1: Insight Into the Chromatin Landscape of the Provirus by Julie Janssens, Anne Bruggemans, Frauke Christ, Zeger Debyser

    Published in Frontiers in Microbiology (2021-03-01)
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  2. 2

    Determinants of Retroviral Integration and Implications for Gene Therapeutic MLV—Based Vectors and for a Cure for HIV-1 Infection by Eline Pellaers, Anayat Bhat, Frauke Christ, Zeger Debyser

    Published in Viruses (2022-12-01)
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  3. 3

    Insight into HIV-2 latency may disclose strategies for a cure for HIV-1 infection by Suha Saleh, Lenard Vranckx, Rik Gijsbers, Frauke Christ, Zeger Debyser

    Published in Journal of Virus Eradication (2017-01-01)
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  4. 4

    Insight in HIV Integration Site Selection Provides a Block-and-Lock Strategy for a Functional Cure of HIV Infection by Zeger Debyser, Gerlinde Vansant, Anne Bruggemans, Julie Janssens, Frauke Christ

    Published in Viruses (2018-12-01)
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  5. 5

    PB1704: LEDGF/P75 ASSOCIATED WITH CHEMORESISTANCE IN MIXED-LINEAGE LEUKEMIA by Muluembet Akele, Siska Van Belle, Alessandro Canella, Frauke Christ, Zeger Debyser

    Published in HemaSphere (2023-08-01)
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  6. 6

    Role of Transportin-SR2 in HIV-1 Nuclear Import by Maryam Tabasi, Ivan Nombela, Julie Janssens, Adrien P. Lahousse, Frauke Christ, Zeger Debyser

    Published in Viruses (2021-05-01)
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  7. 7

    The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function by Tine Brouns, Vanda Lux, Siska Van Belle, Frauke Christ, Václav Veverka, Zeger Debyser

    Published in Cells (2024-01-01)
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  8. 8

    The LEDGIN GS-9822 inhibits HIV-2 infection and enhances HIV-2 latency by Anne Bruggemans, Gerlinde Vansant, Eline Pellaers, Paulien Van de Velde, Frauke Christ, Zeger Debyser

    Published in Microbiology Spectrum (2026-06-01)
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  9. 9

    A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication. by Erik Serrao, Wannes Thys, Jonas Demeulemeester, Laith Q Al-Mawsawi, Frauke Christ, Zeger Debyser, Nouri Neamati

    Published in PLoS ONE (2012-01-01)
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  10. 10

    BRD4 modulator ZL0580 and LEDGINs additively block and lock HIV-1 transcription by Eline Pellaers, Julie Janssens, Lore Wils, Alexe Denis, Anayat Bhat, Siska Van Belle, Da Feng, Frauke Christ, Peng Zhan, Zeger Debyser

    Published in Nature Communications (2025-05-01)
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  11. 11

    Identification of Novel 3-Hydroxy-pyran-4-One Derivatives as Potent HIV-1 Integrase Inhibitors Using in silico Structure-Based Combinatorial Library Design Approach by Hajar Sirous, Giulia Chemi, Sandra Gemma, Stefania Butini, Zeger Debyser, Frauke Christ, Lotfollah Saghaie, Simone Brogi, Afshin Fassihi, Giuseppe Campiani, Margherita Brindisi

    Published in Frontiers in Chemistry (2019-08-01)
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  12. 12

    LEDGF/p75-independent HIV-1 replication demonstrates a role for HRP-2 and remains sensitive to inhibition by LEDGINs. by Rik Schrijvers, Jan De Rijck, Jonas Demeulemeester, Noritaka Adachi, Sofie Vets, Keshet Ronen, Frauke Christ, Frederic D Bushman, Zeger Debyser, Rik Gijsbers

    Published in PLoS Pathogens (2012-01-01)
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  13. 13

    Phenotyping of Rare <i>CFTR</i> Mutations Reveals Distinct Trafficking and Functional Defects by Marjolein Ensinck, Liesbeth De Keersmaecker, Lise Heylen, Anabela S. Ramalho, Rik Gijsbers, Ricard Farré, Kris De Boeck, Frauke Christ, Zeger Debyser, Marianne S. Carlon

    Published in Cells (2020-03-01)
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  14. 14

    Novel CFTR modulator combinations maximise rescue of G85E and N1303K in rectal organoids by Marjolein M. Ensinck, Liesbeth De Keersmaecker, Anabela S. Ramalho, Senne Cuyx, Stephanie Van Biervliet, Lieven Dupont, Frauke Christ, Zeger Debyser, François Vermeulen, Marianne S. Carlon

    Published in ERJ Open Research (2022-04-01)
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  15. 15

    LEDGIN-mediated Inhibition of Integrase–LEDGF/p75 Interaction Reduces Reactivation of Residual Latent HIV by Lenard S. Vranckx, Jonas Demeulemeester, Suha Saleh, Annegret Boll, Gerlinde Vansant, Rik Schrijvers, Caroline Weydert, Emilie Battivelli, Eric Verdin, Anna Cereseto, Frauke Christ, Rik Gijsbers, Zeger Debyser

    Published in EBioMedicine (2016-06-01)
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  16. 16

    Correction to: HIV-1 IN/Pol recruits LEDGF/p75 into viral particles by Belete Ayele Desimmie, Caroline Weydert, Rik Schrijvers, Sofie Vets, Jonas Demeulemeester, Paul Proost, Igor Paron, Jan De Rijck, Jan Mast, Norbert Bannert, Rik Gijsbers, Frauke Christ, Zeger Debyser

    Published in Retrovirology (2020-07-01)
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  17. 17

    Unlike its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival by Siska Van Belle, Sara El Ashkar, Kateřina Čermáková, Filip Matthijssens, Steven Goossens, Alessandro Canella, Courtney H. Hodges, Frauke Christ, Jan De Rijck, Pieter Van Vlierberghe, Václav Veverka, Zeger Debyser

    Published in Cells (2021-01-01)
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  18. 18

    BET-Independent Murine Leukemia Virus Integration Is Retargeted In Vivo and Selects Distinct Genomic Elements for Lymphomagenesis by Ivan Nombela, Martine Michiels, Dominique Van Looveren, Lukas Marcelis, Sara el Ashkar, Siska Van Belle, Anne Bruggemans, Thomas Tousseyn, Jürg Schwaller, Frauke Christ, Rik Gijsbers, Jan De Rijck, Zeger Debyser

    Published in Microbiology Spectrum (2022-08-01)
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