Regulatory Interplay between miR-181a-5p and Estrogen Receptor Signaling Cascade in Breast Cancer

by Rosaria Benedetti, Chiara Papulino, Giulia Sgueglia, Ugo Chianese, Tommaso De Marchi, Francesco Iovino, Dante Rotili, Antonello Mai, Emma Niméus, Carmela Dell’ Aversana, Lucia Altucci
Published 2021-02-01

Properly Substituted Cyclic Bis-(2-bromobenzylidene) Compounds Behaved as Dual p300/CARM1 Inhibitors and Induced Apoptosis in Cancer Cells

by Rossella Fioravanti, Stefano Tomassi, Elisabetta Di Bello, Annalisa Romanelli, Andrea Maria Plateroti, Rosaria Benedetti, Mariarosaria Conte, Ettore Novellino, Lucia Altucci, Sergio Valente, Antonello Mai
Published 2020-07-01

Anti-influenza A virus activity and structure–activity relationship of a series of nitrobenzoxadiazole derivatives

by Francesco Fiorentino, Marta De Angelis, Martina Menna, Annarita Rovere, Anna Maria Caccuri, Francesca D’Acunzo, Anna Teresa Palamara, Lucia Nencioni, Dante Rotili, Antonello Mai
Published 2021-01-01

Intergenerational inheritance of high fat diet-induced cardiac lipotoxicity in Drosophila

by Maria Clara Guida, Ryan Tyge Birse, Alessandra Dall’Agnese, Paula Coutinho Toto, Soda Balla Diop, Antonello Mai, Peter D. Adams, Pier Lorenzo Puri, Rolf Bodmer
Published 2019-01-01

KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2

by Elisa Cocco, Manuela Leo, Claudia Canzonetta, Serena Di Vito, Antonello Mai, Dante Rotili, Arianna Di Napoli, Andrea Vecchione, Cosimo De Nunzio, Patrizia Filetici, Antonella Stoppacciaro
Published 2018-04-01

Statins and Histone Deacetylase Inhibitors Affect Lamin A/C – Histone Deacetylase 2 Interaction in Human Cells

by Elisabetta Mattioli, Elisabetta Mattioli, Davide Andrenacci, Davide Andrenacci, Antonello Mai, Sergio Valente, Joke Robijns, Winnok H. De Vos, Cristina Capanni, Cristina Capanni, Giovanna Lattanzi, Giovanna Lattanzi
Published 2019-01-01

Sirtinol treatment reduces inflammation in human dermal microvascular endothelial cells.

by Angela Orecchia, Claudia Scarponi, Francesca Di Felice, Elisa Cesarini, Simona Avitabile, Antonello Mai, Maria Luisa Mauro, Valentina Sirri, Giovanna Zambruno, Cristina Albanesi, Giorgio Camilloni, Cristina M Failla
Published 2011-01-01

Correction: Sirtinol Treatment Reduces Inflammation in Human Dermal Microvascular Endothelial Cells

by Angela Orecchia, Claudia Scarponi, Francesca Di Felice, Elisa Cesarini, Simona Avitabile, Antonello Mai, Maria Luisa Mauro, Valentina Sirri, Giovanna Zambruno, Cristina Albanesi, Giorgio Camilloni, Cristina M. Failla
Published 2011-01-01

A new nitrobenzoxadiazole-based GSTP1-1 inhibitor with a previously unheard of mechanism of action and high stability

by Chiara Fulci, Dante Rotili, Anastasia De Luca, Lorenzo Stella, Blasco Morozzo della Rocca, Mariantonietta Forgione, Veronica Di Paolo, Antonello Mai, Mattia Falconi, Luigi Quintieri, Anna M. Caccuri
Published 2017-01-01

Correction: Sirtinol Treatment Reduces Inflammation in Human Dermal Microvascular Endothelial Cells.

by Angela Orecchia, Claudia Scarponi, Francesca Di Felice, Elisa Cesarini, Simona Avitabile, Antonello Mai, Maria Luisa Mauro, Valentina Sirri, Giovanna Zambruno, Cristina Albanesi, Giorgio Camilloni, Cristina M. Failla
Published 2011-01-01

Amphetamine and the Smart Drug 3,4-Methylenedioxypyrovalerone (MDPV) Induce Generalization of Fear Memory in Rats

by Paola Colucci, Paola Colucci, Giulia Federica Mancini, Giulia Federica Mancini, Alessia Santori, Alessia Santori, Clemens Zwergel, Clemens Zwergel, Antonello Mai, Viviana Trezza, Benno Roozendaal, Benno Roozendaal, Patrizia Campolongo, Patrizia Campolongo
Published 2019-11-01

HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal

by Lucia Rossi, Cecilia Battistelli, Valeria de Turris, Valeria Noce, Clemens Zwergel, Sergio Valente, Alessandra Moioli, Andrea Manzione, Marco Palladino, Veronica Bordoni, Alessandro Domenici, Paolo Menè, Antonello Mai, Marco Tripodi, Raffaele Strippoli
Published 2018-05-01

H19-Dependent Transcriptional Regulation of β3 and β4 Integrins Upon Estrogen and Hypoxia Favors Metastatic Potential in Prostate Cancer

by Lorenza Bacci, Aurora Aiello, Cristian Ripoli, Rossella Loria, Dario Pugliese, Francesco Pierconti, Dante Rotili, Lidia Strigari, Francesco Pinto, Pier Francesco Bassi, Antonello Mai, Claudio Grassi, Alfredo Pontecorvi, Rita Falcioni, Antonella Farsetti, Simona Nanni
Published 2019-08-01

The Pan-Sirtuin Inhibitor MC2494 Regulates Mitochondrial Function in a Leukemia Cell Line

by Vincenzo Carafa, Rosita Russo, Laura Della Torre, Francesca Cuomo, Carmela Dell'Aversana, Carmela Dell'Aversana, Federica Sarno, Giulia Sgueglia, Marzia Di Donato, Dante Rotili, Antonello Mai, Angela Nebbioso, Gilda Cobellis, Angela Chambery, Lucia Altucci
Published 2020-05-01

SIRT5 Inhibition Induces Brown Fat-Like Phenotype in 3T3-L1 Preadipocytes

by Francesca Molinari, Alessandra Feraco, Simone Mirabilii, Serena Saladini, Luigi Sansone, Enza Vernucci, Giada Tomaselli, Vincenzo Marzolla, Dante Rotili, Matteo A. Russo, Maria Rosaria Ricciardi, Agostino Tafuri, Antonello Mai, Massimiliano Caprio, Marco Tafani, Andrea Armani
Published 2021-05-01

Identification of Inhibitors to <i>Trypanosoma cruzi</i> Sirtuins Based on Compounds Developed to Human Enzymes

by Tanira Matutino Bastos, Milena Botelho Pereira Soares, Caio Haddad Franco, Laura Alcântara, Lorenzo Antonini, Manuela Sabatino, Nicola Mautone, Lucio Holanda Freitas-Junior, Carolina Borsoi Moraes, Rino Ragno, Dante Rotili, Sergio Schenkman, Antonello Mai, Nilmar Silvio Moretti
Published 2020-05-01

Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation

by Clemens Zwergel, Rossella Fioravanti, Giulia Stazi, Federica Sarno, Cecilia Battistelli, Annalisa Romanelli, Angela Nebbioso, Eduarda Mendes, Alexandra Paulo, Raffaele Strippoli, Marco Tripodi, Dany Pechalrieu, Paola B. Arimondo, Teresa De Luca, Donatella Del Bufalo, Daniela Trisciuoglio, Lucia Altucci, Sergio Valente, Antonello Mai
Published 2020-02-01

Properly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity.

by Dante Rotili, Domenico Tarantino, Biagina Marrocco, Christina Gros, Véronique Masson, Valérie Poughon, Fréderic Ausseil, Yanqi Chang, Donatella Labella, Sandro Cosconati, Salvatore Di Maro, Ettore Novellino, Michael Schnekenburger, Cindy Grandjenette, Celine Bouvy, Marc Diederich, Xiaodong Cheng, Paola B Arimondo, Antonello Mai
Published 2014-01-01

Downregulation of miR‐326 and its host gene β‐arrestin1 induces pro‐survival activity of E2F1 and promotes medulloblastoma growth

by Evelina Miele, Agnese Po, Angela Mastronuzzi, Andrea Carai, Zein Mersini Besharat, Natalia Pediconi, Luana Abballe, Giuseppina Catanzaro, Claudia Sabato, Enrico De Smaele, Gianluca Canettieri, Lucia Di Marcotullio, Alessandra Vacca, Antonello Mai, Massimo Levrero, Stefan M. Pfister, Marcel Kool, Felice Giangaspero, Franco Locatelli, Elisabetta Ferretti
Published 2021-02-01

Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma...

by Vitor Coutinho Carneiro, Isabel Caetano de Abreu da Silva, Murilo Sena Amaral, Adriana S A Pereira, Gilbert Oliveira Silveira, David da Silva Pires, Sergio Verjovski-Almeida, Frank J Dekker, Dante Rotili, Antonello Mai, Eduardo José Lopes-Torres, Dina Robaa, Wolfgang Sippl, Raymond J Pierce, M Teresa Borrello, A Ganesan, Julien Lancelot, Silvana Thiengo, Monica Ammon Fernandez, Amanda Roberta Revoredo Vicentino, Marina Moraes Mourão, Fernanda Sales Coelho, Marcelo Rosado Fantappié
Published 2020-07-01