Epigenetic changes modulate schistosome egg formation and are a novel target for reducing transmission of schistosomiasis.

by Vitor Coutinho Carneiro, Isabel Caetano de Abreu da Silva, Eduardo José Lopes Torres, Stephany Caby, Julien Lancelot, Mathieu Vanderstraete, Silviya D Furdas, Manfred Jung, Raymond J Pierce, Marcelo Rosado Fantappié
Published 2014-05-01

CK2 phosphorylation of Schistosoma mansoni HMGB1 protein regulates its cellular traffic and secretion but not its DNA transactions.

by Isabel Caetano de Abreu da Silva, Vitor Coutinho Carneiro, Renata de Moraes Maciel, Rodrigo Furtado Madeiro da Costa, Daniel Rodrigues Furtado, Francisco Meirelles Bastos de Oliveira, Mário Alberto Cardoso da Silva-Neto, Franklin David Rumjanek, Marcelo Rosado Fantappié
Published 2011-01-01

The dengue vector Aedes aegypti contains a functional high mobility group box 1 (HMGB1) protein with a unique regulatory C-terminus.

by Fabio Schneider Ribeiro, Isabel Caetano de Abreu da Silva, Vitor Coutinho Carneiro, Fabrício dos Santos Belgrano, Ronaldo Mohana-Borges, Ivone de Andrade Rosa, Marlene Benchimol, Nathalia Rocha Quintino Souza, Rafael Dias Mesquita, Marcos Henrique Ferreira Sorgine, Felipe Gazos-Lopes, Amanda Roberta Revoredo Vicentino, Wenjie Wu, Renata de Moraes Maciel, Mario Alberto Cardoso da Silva-Neto, Marcelo Rosado Fantappié
Published 2012-01-01

Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma...

by Vitor Coutinho Carneiro, Isabel Caetano de Abreu da Silva, Murilo Sena Amaral, Adriana S A Pereira, Gilbert Oliveira Silveira, David da Silva Pires, Sergio Verjovski-Almeida, Frank J Dekker, Dante Rotili, Antonello Mai, Eduardo José Lopes-Torres, Dina Robaa, Wolfgang Sippl, Raymond J Pierce, M Teresa Borrello, A Ganesan, Julien Lancelot, Silvana Thiengo, Monica Ammon Fernandez, Amanda Roberta Revoredo Vicentino, Marina Moraes Mourão, Fernanda Sales Coelho, Marcelo Rosado Fantappié
Published 2020-07-01