On the path to 2025: understanding the Alzheimer’s disease continuum

by Paul S. Aisen, Jeffrey Cummings, Clifford R. Jack, John C. Morris, Reisa Sperling, Lutz Frölich, Roy W. Jones, Sherie A. Dowsett, Brandy R. Matthews, Joel Raskin, Philip Scheltens, Bruno Dubois
Published 2017-08-01

Aptamarker prediction of brain amyloid-β status in cognitively normal individuals at risk for Alzheimer's disease.

by Gregory Penner, Soizic Lecocq, Anaëlle Chopin, Ximena Vedoya, Simone Lista, Andrea Vergallo, Enrica Cavedo, Francois-Xavier Lejeune, Bruno Dubois, Harald Hampel, INSIGHT-preAD study group, Alzheimer Precision Medicine Initiative (APMI)
Published 2021-01-01

Testing the therapeutic effects of transcranial direct current stimulation (tDCS) in semantic dementia: a double blind, sham controlled, randomized clinical trial

by Clara Sanches, Richard Levy, Sarah Benisty, Lisette Volpe-Gillot, Marie-Odile Habert, Aurelie Kas, Sébastian Ströer, Nadya Pyatigorskaya, Anna Kaglik, Angelina Bourbon, Bruno Dubois, Raffaella Migliaccio, Antoni Valero-Cabré, Marc Teichmann
Published 2019-11-01

Multi-omics signature of brain amyloid deposition in asymptomatic individuals at-risk for Alzheimer's disease: The INSIGHT-preAD studyResearch in context

by Laura Xicota, Farid Ichou, François-Xavier Lejeune, Benoit Colsch, Arthur Tenenhaus, Inka Leroy, Gaëlle Fontaine, Marie Lhomme, Hugo Bertin, Marie-Odile Habert, Stéphane Epelbaum, Bruno Dubois, Fanny Mochel, Marie-Claude Potier
Published 2019-09-01

Detection of volume loss in hippocampal layers in Alzheimer's disease using 7 T MRI: A feasibility study

by Claire Boutet, Marie Chupin, Stéphane Lehéricy, Linda Marrakchi-Kacem, Stéphane Epelbaum, Cyril Poupon, Christopher Wiggins, Alexandre Vignaud, Dominique Hasboun, Bénédicte Defontaines, Olivier Hanon, Bruno Dubois, Marie Sarazin, Lucie Hertz-Pannier, Olivier Colliot
Published 2014-01-01

MiRNA-15b and miRNA-125b are associated with regional Aβ-PET and FDG-PET uptake in cognitively normal individuals with subjective memory complaints

by Andrea Vergallo, Simone Lista, Yuhai Zhao, Pablo Lemercier, Stefan J. Teipel, Marie-Claude Potier, Marie-Odile Habert, Bruno Dubois, Walter J. Lukiw, Harald Hampel, for the INSIGHT-preAD study group, the Alzheimer Precision Medicine Initiative (APMI)
Published 2021-01-01

Correction to: A phase III randomized trial of gantenerumab in prodromal Alzheimer’s disease

by Susanne Ostrowitzki, Robert A. Lasser, Ernest Dorflinger, Philip Scheltens, Frederik Barkhof, Tania Nikolcheva, Elizabeth Ashford, Sylvie Retout, Carsten Hofmann, Paul Delmar, Gregory Klein, Mirjana Andjelkovic, Bruno Dubois, Mercè Boada, Kaj Blennow, Luca Santarelli, Paulo Fontoura, for the SCarlet RoAD Investigators
Published 2018-09-01

A phase III randomized trial of gantenerumab in prodromal Alzheimer’s disease

by Susanne Ostrowitzki, Robert A. Lasser, Ernest Dorflinger, Philip Scheltens, Frederik Barkhof, Tania Nikolcheva, Elizabeth Ashford, Sylvie Retout, Carsten Hofmann, Paul Delmar, Gregory Klein, Mirjana Andjelkovic, Bruno Dubois, Mercè Boada, Kaj Blennow, Luca Santarelli, Paulo Fontoura, for the SCarlet RoAD Investigators
Published 2017-12-01

Age and sex impact plasma NFL and t-Tau trajectories in individuals with subjective memory complaints: a 3-year follow-up study

by Filippo Baldacci, Simone Lista, Maria Laura Manca, Patrizia A. Chiesa, Enrica Cavedo, Pablo Lemercier, Henrik Zetterberg, Kaj Blennow, Marie-Odile Habert, Marie Claude Potier, Bruno Dubois, Andrea Vergallo, Harald Hampel, the INSIGHT-preAD study group, for the Alzheimer Precision Medicine Initiative (APMI)
Published 2020-11-01

Applicability of in vivo staging of regional amyloid burden in a cognitively normal cohort with subjective memory complaints: the INSIGHT-preAD study

by Fatemah A. Sakr, Michel J. Grothe, Enrica Cavedo, Irina Jelistratova, Marie-Odile Habert, Martin Dyrba, Gabriel Gonzalez-Escamilla, Hugo Bertin, Maxime Locatelli, Stephane Lehericy, Stefan Teipel, Bruno Dubois, Harald Hampel, for the INSIGHT-preAD study group, the Alzheimer Precision Medicine Initiative (APMI)
Published 2019-01-01

How many patients are eligible for disease-modifying treatment in Alzheimer’s disease? A French national observational study over 5 years

by Didier Hannequin, Florence Pasquier, Bruno Dubois, David Wallon, Julien Dumurgier, Stéphane Epelbaum, Thérèse Jonveaux, Annick Besozzi, Stéphane Pouponneau, Caroline Hommet, Laetitia Berly, Adrien Julian, Marc Paccalin, Julie Bellet, Claire Boutoleau-Bretonniere, Thiphaine Charriau, Olivier Rouaud, Olivier Madec, Aurélie Mouton, Renaud David, Samir Bekadar, Roxane Fabre, Walter Deberdt
Published 2019-06-01

The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: consensus document of the Joint Program for Neurodegenerative D...

by Alberto Costa, Thomas Bak, Paolo Caffarra, Carlo Caltagirone, Mathieu Ceccaldi, Fabienne Collette, Sebastian Crutch, Sergio Della Sala, Jean François Démonet, Bruno Dubois, Emrah Duzel, Peter Nestor, Sokratis G. Papageorgiou, Eric Salmon, Sietske Sikkes, Pietro Tiraboschi, Wiesje M. van der Flier, Pieter Jelle Visser, Stefano F. Cappa
Published 2017-04-01

Semantic loss marks early Alzheimer's disease‐related neurodegeneration in older adults without dementia

by Jet M. J. Vonk, Vincent Bouteloup, Jean‐François Mangin, Bruno Dubois, Frédéric Blanc, Audrey Gabelle, Mathieu Ceccaldi, Cédric Annweiler, Pierre Krolak‐Salmon, Catherine Belin, Thérèse Rivasseau‐Jonveaux, Adrien Julian, François Sellal, Eloi Magnin, Marie Chupin, Marie‐Odile Habert, Geneviève Chêne, Carole Dufouil, and on behalf of the MEMENTO cohort Study Group
Published 2020-01-01

The influence of diversity on the measurement of functional impairment: An international validation of the Amsterdam IADL Questionnaire in eight countries

by Mark A. Dubbelman, Merike Verrijp, David Facal, Gonzalo Sánchez‐Benavides, Laura J.E. Brown, Wiesje M. vander Flier, Hanna Jokinen, Athene Lee, Iracema Leroi, Cristina Lojo‐Seoane, Vuk Milošević, José Luís Molinuevo, Arturo X. Pereiro Rozas, Craig Ritchie, Stephen Salloway, Gemma Stringer, Stelios Zygouris, Bruno Dubois, Stéphane Epelbaum, Philip Scheltens, Sietske A.M. Sikkes
Published 2020-01-01

Cognitive and imaging markers in non-demented subjects attending a memory clinic: study design and baseline findings of the MEMENTO cohort

by Carole Dufouil, Bruno Dubois, Bruno Vellas, Florence Pasquier, Frédéric Blanc, Jacques Hugon, Olivier Hanon, Jean-François Dartigues, Sandrine Harston, Audrey Gabelle, Mathieu Ceccaldi, Olivier Beauchet, Pierre Krolak-Salmon, Renaud David, Olivier Rouaud, Olivier Godefroy, Catherine Belin, Isabelle Rouch, Nicolas Auguste, David Wallon, Athanase Benetos, Jérémie Pariente, Marc Paccalin, Olivier Moreaud, Caroline Hommet, François Sellal, Claire Boutoleau-Bretonniére, Isabelle Jalenques, Armelle Gentric, Pierre Vandel, Chabha Azouani, Ludovic Fillon, Clara Fischer, Helen Savarieau, Gregory Operto, Hugo Bertin, Marie Chupin, Vincent Bouteloup, Marie-Odile Habert, Jean-François Mangin, Geneviève Chêne, on behalf of the MEMENTO cohort Study Group
Published 2017-08-01

Comparison of Pittsburgh compound B and florbetapir in cross‐sectional and longitudinal studies

by Yi Su, Shaney Flores, Guoqiao Wang, Russ C. Hornbeck, Benjamin Speidel, Nelly Joseph‐Mathurin, Andrei G. Vlassenko, Brian A. Gordon, Robert A. Koeppe, William E. Klunk, Clifford R. Jack Jr., Martin R. Farlow, Stephen Salloway, Barbara J. Snider, Sarah B. Berman, Erik D. Roberson, Jared Brosch, Ivonne Jimenez‐Velazques, Christopher H. vanDyck, Douglas Galasko, Shauna H. Yuan, Suman Jayadev, Lawrence S. Honig, Serge Gauthier, Ging‐Yuek R. Hsiung, Mario Masellis, William S. Brooks, Michael Fulham, Roger Clarnette, Colin L. Masters, David Wallon, Didier Hannequin, Bruno Dubois, Jeremie Pariente, Raquel Sanchez‐Valle, Catherine Mummery, John M. Ringman, Michel Bottlaender, Gregory Klein, Smiljana Milosavljevic‐Ristic, Eric McDade, Chengjie Xiong, John C. Morris, Randall J. Bateman, Tammie L.S. Benzinger
Published 2019-12-01