The role of the jaw subdomain of peptidoglycan glycosyltransferases for lipid II polymerization

by Avinash S. Punekar, Firdaus Samsudin, Adrian J. Lloyd, Christopher G. Dowson, David J. Scott, Syma Khalid, David I. Roper
Published 2018-06-01

Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing.

by Elena S Lysenko, Thomas B Clarke, Mikhail Shchepetov, Adam J Ratner, David I Roper, Christopher G Dowson, Jeffrey N Weiser
Published 2007-08-01

Bacterial Lipid II Analogs: Novel In Vitro Substrates for Mammalian Oligosaccharyl Diphosphodolichol Diphosphatase (DLODP) Activities

by Ahmad Massarweh, Michael Bosco, Isabelle Chantret, Thibaut Léger, Layla Jamal, David I. Roper, Christopher G. Dowson, Patricia Busca, Ahmed Bouhss, Christine Gravier-Pelletier, Stuart E. H. Moore
Published 2019-06-01

In vitro characterization of the antivirulence target of Gram-positive pathogens, peptidoglycan O-acetyltransferase A (OatA).

by David Sychantha, Carys S Jones, Dustin J Little, Patrick J Moynihan, Howard Robinson, Nicola F Galley, David I Roper, Christopher G Dowson, P Lynne Howell, Anthony J Clarke
Published 2017-10-01

There is no market for new antibiotics: this allows an open approach to research and development [version 1; peer review: 2 approved]

by Dana M. Klug, Fahima I. M. Idiris, Mark A. T. Blaskovich, Frank von Delft, Christopher G. Dowson, Claas Kirchhelle, Adam P. Roberts, Andrew C. Singer, Matthew H. Todd
Published 2021-06-01

Investigating Bacteriophages Targeting the Opportunistic Pathogen <i>Acinetobacter baumannii</i>

by Kathryn M. Styles, Rapee Thummeepak, Udomluk Leungtongkam, Sophie E. Smith, Gabrielle S. Christie, Andrew Millard, John Moat, Christopher G. Dowson, Elizabeth M. H. Wellington, Sutthirat Sitthisak, Antonia P. Sagona
Published 2020-04-01

Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin

by Laura C. Jacques, Stavros Panagiotou, Murielle Baltazar, Madikay Senghore, Shadia Khandaker, Rong Xu, Laura Bricio-Moreno, Marie Yang, Christopher G. Dowson, Dean B. Everett, Daniel R. Neill, Aras Kadioglu
Published 2020-04-01

Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine

by Sarah Batson, Cesira de Chiara, Vita Majce, Adrian J. Lloyd, Stanislav Gobec, Dean Rea, Vilmos Fülöp, Christopher W. Thoroughgood, Katie J. Simmons, Christopher G. Dowson, Colin W. G. Fishwick, Luiz Pedro S. de Carvalho, David I. Roper
Published 2017-12-01

Novel Corynebacterium diphtheriae in Domestic Cats

by Aron J. Hall, Pamela K. Cassiday, Kathryn A. Bernard, Frances Bolt, Arnold G. Steigerwalt, Danae Bixler, Lucia C. Pawloski, Anne M. Whitney, Masaaki Iwaki, Adam Baldwin, Christopher G. Dowson, Takako Komiya, Motohide Takahashi, Hans P. Hinrikson, Maria L. Tondella
Published 2010-04-01

A role for sigma factor SigE in Corynebacterium pseudotuberculosis resistance to nitric oxide/ peroxide stress

by Luis G. C. Pacheco, Luis G. C. Pacheco, Thiago L. P. Castro, Rodrigo D. Carvalho, Pablo M. Moraes, Fernanda A. Dorella, Natalia B. Carvalho, Susan E. Slade, James H Scrivens, Martin eFeelisch, Roberto eMeyer, Anderson eMiyoshi, Sergio C. Oliveira, Christopher G. Dowson, Vasco A. C. Azevedo
Published 2012-04-01

Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis

by Anh T. Tran, Emma E. Watson, Venugopal Pujari, Trent Conroy, Luke J. Dowman, Andrew M. Giltrap, Angel Pang, Weng Ruh Wong, Roger G. Linington, Sebabrata Mahapatra, Jessica Saunders, Susan A. Charman, Nicholas P. West, Timothy D. H. Bugg, Julie Tod, Christopher G. Dowson, David I. Roper, Dean C. Crick, Warwick J. Britton, Richard J. Payne
Published 2017-03-01

Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis.

by Matthew T G Holden, Heidi Hauser, Mandy Sanders, Thi Hoa Ngo, Inna Cherevach, Ann Cronin, Ian Goodhead, Karen Mungall, Michael A Quail, Claire Price, Ester Rabbinowitsch, Sarah Sharp, Nicholas J Croucher, Tran Bich Chieu, Nguyen Thi Hoang Mai, To Song Diep, Nguyen Tran Chinh, Michael Kehoe, James A Leigh, Philip N Ward, Christopher G Dowson, Adrian M Whatmore, Neil Chanter, Pernille Iversen, Marcelo Gottschalk, Josh D Slater, Hilde E Smith, Brian G Spratt, Jianguo Xu, Changyun Ye, Stephen Bentley, Barclay G Barrell, Constance Schultsz, Duncan J Maskell, Julian Parkhill
Published 2009-07-01