Multiple communication mechanisms between sensor kinases are crucial for virulence in Pseudomonas aeruginosa

by Vanessa I. Francis, Elaine M. Waters, Sutharsan E. Finton-James, Andrea Gori, Aras Kadioglu, Alan R. Brown, Steven L. Porter
Published 2018-06-01

Streptococcus pneumoniae detects and responds to foreign bacterial peptide fragments in its environment

by Lucy J. Hathaway, Patrick Bättig, Sandra Reber, Jeannine U. Rotzetter, Suzanne Aebi, Christoph Hauser, Manfred Heller, Aras Kadioglu, Kathrin Mühlemann
Published 2014-01-01

The pneumococcal polysaccharide capsule and pneumolysin differentially affect CXCL8 and IL-6 release from cells of the upper and lower respiratory tract.

by Eliane Küng, William R Coward, Daniel R Neill, Hesham A Malak, Kathrin Mühlemann, Aras Kadioglu, Markus Hilty, Lucy J Hathaway
Published 2014-01-01

Streptolysin O concentration and activity is central to in vivo phenotype and disease outcome in Group A Streptococcus infection

by Jenny Clarke, Murielle Baltazar, Mansoor Alsahag, Stavros Panagiotou, Marion Pouget, William A. Paxton, Georgios Pollakis, Dean Everett, Neil French, Aras Kadioglu
Published 2021-09-01

Intestinal helminth co-infection is an unrecognised risk factor for increased pneumococcal carriage density and invasive disease

by Alice E. Law, Rebecca K. Shears, Andrea A. Lopez Rodas, Richard K. Grencis, Philip J. Cooper, Daniel R. Neill, Aras Kadioglu
Published 2021-03-01

Circulating Pneumolysin Is a Potent Inducer of Cardiac Injury during Pneumococcal Infection.

by Yasir Alhamdi, Daniel R Neill, Simon T Abrams, Hesham A Malak, Reham Yahya, Richard Barrett-Jolley, Guozheng Wang, Aras Kadioglu, Cheng-Hock Toh
Published 2015-05-01

Capsule type of Streptococcus pneumoniae determines growth phenotype.

by Lucy J Hathaway, Silvio D Brugger, Brigitte Morand, Mathieu Bangert, Jeannine U Rotzetter, Christoph Hauser, Werner A Graber, Suzanna Gore, Aras Kadioglu, Kathrin Mühlemann
Published 2012-01-01

Author Correction: Hypervirulent pneumococcal serotype 1 harbours two pneumolysin variants with differential haemolytic activity

by Stavros Panagiotou, Chrispin Chaguza, Reham Yahya, Teerawit Audshasai, Murielle Baltazar, Lorenzo Ressel, Shadia Khandaker, Mansoor Alsahag, Tim J. Mitchell, Marc Prudhomme, Aras Kadioglu, Marie Yang
Published 2021-03-01

Correction: The AgI/II Family Adhesin AspA Is Required for Respiratory Infection by Streptococcus pyogenes

by Linda Franklin, Angela H. Nobbs, Laura Bricio-Moreno, Christopher J. Wright, Sarah E. Maddocks, Jaspreet Singh Sahota, Joe Ralph, Matthew O’Connor, Howard F. Jenkinson, Aras Kadioglu
Published 2013-01-01

The AgI/II family adhesin AspA is required for respiratory infection by Streptococcus pyogenes.

by Linda Franklin, Angela H Nobbs, Laura Bricio-Moreno, Christopher J Wright, Sarah E Maddocks, Jaspreet Singh Sahota, Joe Ralph, Matthew O'Connor, Howard F Jenkinson, Aras Kadioglu
Published 2013-01-01

Correction: The AgI/II Family Adhesin AspA Is Required for Respiratory Infection by.

by Linda Franklin, Angela H. Nobbs, Laura Bricio-Moreno, Christopher J. Wright, Sarah E. Maddocks, Jaspreet Singh Sahota, Joe Ralph, Matthew O’Connor, Howard F. Jenkinson, Aras Kadioglu
Published 2013-01-01

T regulatory cells control susceptibility to invasive pneumococcal pneumonia in mice.

by Daniel R Neill, Vitor E Fernandes, Laura Wisby, Andrew R Haynes, Daniela M Ferreira, Ameera Laher, Natalie Strickland, Stephen B Gordon, Paul Denny, Aras Kadioglu, Peter W Andrew
Published 2012-01-01

Increased pathogenicity of pneumococcal serotype 1 is driven by rapid autolysis and release of pneumolysin

by Laura C. Jacques, Stavros Panagiotou, Murielle Baltazar, Madikay Senghore, Shadia Khandaker, Rong Xu, Laura Bricio-Moreno, Marie Yang, Christopher G. Dowson, Dean B. Everett, Daniel R. Neill, Aras Kadioglu
Published 2020-04-01

The B lymphocyte differentiation factor (BAFF) is expressed in the airways of children with CF and in lungs of mice infected with Pseudomonas aeruginosa.

by Daniel R Neill, Gemma L Saint, Laura Bricio-Moreno, Joanne L Fothergill, Kevin W Southern, Craig Winstanley, Stephen E Christmas, Stephen E Christmas, Joseph R Slupsky, Paul S McNamara, Aras Kadioglu, Brian F Flanagan
Published 2014-01-01

Recombination in Streptococcus pneumoniae Lineages Increase with Carriage Duration and Size of the Polysaccharide Capsule

by Chrispin Chaguza, Cheryl P. Andam, Simon R. Harris, Jennifer E. Cornick, Marie Yang, Laura Bricio-Moreno, Arox W. Kamng’ona, Julian Parkhill, Neil French, Robert S. Heyderman, Aras Kadioglu, Dean B. Everett, Stephen D. Bentley, William P. Hanage
Published 2016-09-01

The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection.

by Youssif M Ali, Nicholas J Lynch, Kashif S Haleem, Teizo Fujita, Yuichi Endo, Soren Hansen, Uffe Holmskov, Kazue Takahashi, Gregory L Stahl, Thomas Dudler, Umakhanth V Girija, Russell Wallis, Aras Kadioglu, Cordula M Stover, Peter W Andrew, Wilhelm J Schwaeble
Published 2012-01-01

Evolutionary trade-offs associated with loss of PmrB function in host-adapted Pseudomonas aeruginosa

by Laura Bricio-Moreno, Victoria H. Sheridan, Ian Goodhead, Stuart Armstrong, Janet K.L. Wong, Elaine M. Waters, Joscelyn Sarsby, Stavros Panagiotou, James Dunn, Adrita Chakraborty, Yongliang Fang, Karl E. Griswold, Craig Winstanley, Joanne L. Fothergill, Aras Kadioglu, Daniel R. Neill
Published 2018-07-01

Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.

by Edel A McNeela, Aine Burke, Daniel R Neill, Cathy Baxter, Vitor E Fernandes, Daniela Ferreira, Sarah Smeaton, Rana El-Rachkidy, Rachel M McLoughlin, Andres Mori, Barry Moran, Katherine A Fitzgerald, Jurg Tschopp, Virginie Pétrilli, Peter W Andrew, Aras Kadioglu, Ed C Lavelle
Published 2010-11-01

Understanding pneumococcal serotype 1 biology through population genomic analysis

by Chrispin Chaguza, Jennifer E. Cornick, Simon R. Harris, Cheryl P. Andam, Laura Bricio-Moreno, Marie Yang, Feyruz Yalcin, Sani Ousmane, Shanil Govindpersad, Madikay Senghore, Chinelo Ebruke, Mignon Du Plessis, Anmol M. Kiran, Gerd Pluschke, Betuel Sigauque, Lesley McGee, Keith P. Klugman, Paul Turner, Jukka Corander, Julian Parkhill, Jean-Marc Collard, Martin Antonio, Anne von Gottberg, Robert S. Heyderman, Neil French, Aras Kadioglu, William P. Hanage, Dean B. Everett, Stephen D. Bentley, for the PAGe Consortium
Published 2016-11-01