Genetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infection.

by Magda S Jonczyk, Michelle Simon, Saumya Kumar, Vitor E Fernandes, Nicolas Sylvius, Ann-Marie Mallon, Paul Denny, Peter W Andrew
Published 2014-01-01

The B-cell inhibitory receptor CD22 is a major factor in host resistance to Streptococcus pneumoniae infection.

by Vitor E Fernandes, Giuseppe Ercoli, Alan Bénard, Carolin Brandl, Hannah Fahnenstiel, Jennifer Müller-Winkler, Georg F Weber, Paul Denny, Lars Nitschke, Peter W Andrew
Published 2020-04-01

T regulatory cells control susceptibility to invasive pneumococcal pneumonia in mice.

by Daniel R Neill, Vitor E Fernandes, Laura Wisby, Andrew R Haynes, Daniela M Ferreira, Ameera Laher, Natalie Strickland, Stephen B Gordon, Paul Denny, Aras Kadioglu, Peter W Andrew
Published 2012-01-01

Host glycan sugar-specific pathways in Streptococcus pneumoniae: galactose as a key sugar in colonisation and infection [corrected].

by Laura Paixão, Joana Oliveira, André Veríssimo, Susana Vinga, Eva C Lourenço, M Rita Ventura, Morten Kjos, Jan-Willem Veening, Vitor E Fernandes, Peter W Andrew, Hasan Yesilkaya, Ana Rute Neves
Published 2015-01-01

Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.

by Edel A McNeela, Aine Burke, Daniel R Neill, Cathy Baxter, Vitor E Fernandes, Daniela Ferreira, Sarah Smeaton, Rana El-Rachkidy, Rachel M McLoughlin, Andres Mori, Barry Moran, Katherine A Fitzgerald, Jurg Tschopp, Virginie Pétrilli, Peter W Andrew, Aras Kadioglu, Ed C Lavelle
Published 2010-11-01