Large-scale identification of genetic design strategies using local search

by Lun, Desmond S., Rockwell, Graham, Guido, Nicholas J., Baym, Michael Hartmann, Kelner, Jonathan Adam, Berger, Bonnie, Galagan, James E., Church, George M.
Published 2011

Measuring Cation Dependent DNA Polymerase Fidelity Landscapes by Deep Sequencing

by Zamft, Bradley Michael, Marblestone, Adam Henry, Kording, Konrad P., Schmidt, Daniel, Tyo, Keith, Church, George M., Martin Alarcon, Daniel Alberto, Boyden, Edward
Published 2013

Statistical Analysis of Molecular Signal Recording

by Glaser, Joshua I., Zamft, Bradley M., Marblestone, Adam Henry, Moffitt, Jeffrey R., Tyo, Keith, Church, George M., Kording, Konrad P., Boyden, Edward
Published 2013

High-throughput functional variant screens via in vivo production of single-stranded DNA

by Schubert, Max G, Goodman, Daniel B, Wannier, Timothy M, Kaur, Divjot, Farzadfard, Fahim, Lu, Timothy K, Shipman, Seth L, Church, George M
Published 2022

Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection

by Carr, Peter A., Sr, Wang, Harris H., Sterling, Bram Henry, Isaacs, Farren J., Lajoie, Marc J., Xu, George Jing, Church, George M., Jacobson, Joseph
Published 2012

Precise Cas9 targeting enables genomic mutation prevention

by Chavez, Alejandro, Pruitt, Benjamin W., Tuttle, Marcelle, Cecchi, Ryan J., Winston, Jordan, Turczyk, Brian M., Tung, Michael, Collins, James J., Church, George M, Shapiro, Rebecca
Published 2018

Daisy-chain gene drives for the alteration of local populations

by Noble, Charleston, Min, John, Olejarz, Jason, Buchthal, Joanna, Chavez, Alejandro, Smidler, Andrea L., DeBenedictis, Erika A., Church, George M., Nowak, Martin A., Esvelt, Kevin Michael
Published 2020

Optical control of mammalian endogenous transcription and epigenetic states

by Church, George M., Konermann, Silvana M, Brigham, Mark D, Trevino, Alexandro E., Hsu, Patrick, Heidenreich, Matthias, Cong, Le, Platt, Randall Jeffrey, Scott, David Arthur, Zhang, Feng
Published 2017

Optical control of mammalian endogenous transcription and epigenetic states

by Konermann, Silvana M., Brigham, Mark D., Trevino, Alexandro E., Hsu, Patrick, Heidenreich, Matthias, Cong, Le, Platt, Randall Jeffrey, Scott, David Arthur, Church, George M., Zhang, Feng
Published 2016

Engineering and optimising deaminase fusions for genome editing

by Yang, Luhan, Briggs, Adrian W., Chew, Wei Leong, Mali, Prashant, Guell, Marc, Aach, John, Kan, Yinan, Lesha, Emal, Soundararajan, Venkataramanan, Goodman, Daniel Bryan, Cox, David, Church, George M, Zhang, Feng
Published 2017

Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

by Napolitano, Michael G., Landon, Matthieu, Gregg, Christopher J., Lajoie, Marc J., Govindarajan, Lakshmi, Mosberg, Joshua A., Kuznetsov, Gleb, Vargas-Rodriguez, Oscar, Isaacs, Farren J., Söll, Dieter, Goodman, Daniel Bryan, Church, George M
Published 2017

Rapid neurogenesis through transcriptional activation in human stem cells

by Guye, Patrick, Li, Yinqing, Weiss, Ron, Busskamp, Volker, Lewis, Nathan E., Ng, Alex H. M., Shipman, Seth L., Byrne, Susan M., Li, Shangzhong, Stadler, Michael, Murn, Jernej, Sanjana, Neville E, Church, George M
Published 2014

A CRISPR-Cas9-based gene drive platform for genetic interaction analysis in Candida albicans

by Shapiro, Rebecca S., Chavez, Alejandro, Porter, Caroline B. M., Hamblin, Meagan, Kaas, Christian S., DiCarlo, James E., Zeng, Guisheng, Xu, Xiaoli, Revtovich, Alexey V., Kirienko, Natalia V., Wang, Yue, Church, George M., Collins, James J.
Published 2018

REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease

by Meyer, Katharina, Feldman, Heather M., Lu, Tao, Drake, Derek, Lim, Elaine T., Ling, King-Hwa, Bishop, Nicholas A., Pan, Ying, Seo, Jinsoo, Lin, Yuan-Ta, Su, Susan C. (Susan Chih-Chieh), Church, George M., Tsai, Li-Huei, Yankner, Bruce A.
Published 2020

Rapid Sequential in Situ Multiplexing with DNA Exchange Imaging in Neuronal Cells and Tissues

by Wang, Yu, Woehrstein, Johannes B., Donoghue, Noah, Dai, Mingjie, Avendaño, Maier S., Schackmann, Ron C. J., Zoeller, Jason J., Wang, Shan Shan H., Tillberg, Paul W., Park, Demian, Lapan, Sylvain W., Boyden, Edward, Brugge, Joan S., Kaeser, Pascal S., Church, George M., Agasti, Sarit S., Jungmann, Ralf, Yin, Peng
Published 2020

Highly efficient Cas9-mediated transcriptional programming

by Chavez, Alejandro, Scheiman, Jonathan, Tuttle, Marcelle, Lin, Shuailiang, Kiani, Samira, Ter-Ovanesyan, Dmitry, Davidsohn, Noah, Perrimon, Norbert, Weiss, Ron, Aach, John, Vora, Suhani Deepak, Pruitt, Benjamin W., Iyer, Eswar P. R., Guzman, Christopher D., Wiegand, Daniel J., Braff, Jonathan L., Housden, Benjamin E., Collins, James J., Church, George M.
Published 2015

An enhanced CRISPR repressor for targeted mammalian gene regulation

by Yeo, Nan Cher, Chavez, Alejandro, Lance-Byrne, Alissa, Chan, Yingleong, Menn, David, Milanova, Denitsa, Kuo, Chih-Chung, Guo, Xiaoge, Sharma, Sumana, Tung, Angela, Cecchi, Ryan J., Tuttle, Marcelle, Pradhan, Swechchha, Lim, Elaine T., Davidsohn, Noah, Ebrahimkhani, Mo R., Lewis, Nathan E., Kiani, Samira, Church, George M., Collins, James J.
Published 2019

Physical principles for scalable neural recording

by Marblestone, Adam Henry, Zamft, Bradley M., Shapiro, Mikhail G., Cybulski, Thaddeus R., Glaser, Joshua I., Amodei, Dario, Stranges, P. Benjamin, Kalhor, Reza, Seo, Dongjin, Alon, Elad, Maharbiz, Michel M., Carmena, Jose M., Rabaey, Jan M., Church, George M., Kording, Konrad P., Dalrymple, David Allen, Maguire, Yael G. 1975-, Boyden, Edward
Published 2013

Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing

by Tsioris, Konstantinos, Gupta, Namita T., Ogunniyi, Adebola Oluwakayode, Qian, Feng, Yao, Yi, Wang, Xiaomei, Stern, Joel N. H., Chari, Raj, Briggs, Adrian W., Clouser, Christopher R., Vigneault, Francois, Church, George M., Garcia, Melissa N., Murray, Kristy O., Montgomery, Ruth R., Kleinstein, Steven H., Love, J. Christopher, Zimnisky, Ross Martin, Love, J. Christopher
Published 2016

High-resolution antibody dynamics of vaccine-induced immune responses

by Laserson, Uri, Vigneault, Francois, Gadala-Maria, Daniel, Yaari, Gur, Uduman, Mohamed, Vander Heiden, Jason A., Kelton, William, Jung, Sang Taek, Liu, Yi, Laserson, Jonathan, Chari, Raj, Lee, Je-Hyuk, Bachelet, Ido, Hickey, Brendan, Lieberman-Aiden, Erez, Hanczaruk, Bozena, Simen, Birgitte B., Egholm, Michael, Koller, Daphne, Georgiou, George, Kleinstein, Steven H., Church, George M
Published 2014