CRISPR transcriptional repression devices and layered circuits in mammalian cells

by Kiani, Samira, Beal, Jacob, Huh, Jin, Xie, Zhen, Li, Yinqing, Weiss, Ron, Ebrahimkhani, Mohammad Reza, Hall, Richard N.
Published 2015

Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6

by Guye, Patrick, Kipniss, Nathan, Velazquez, Jeremy J., Schoenfeld, Eldi, Kiani, Samira, Griffith, Linda G., Weiss, Ron, Ebrahimkhani, Mohammad Reza
Published 2016

Cas9 gRNA engineering for genome editing, activation and repression

by Chavez, Alejandro, Tuttle, Marcelle, Chari, Raj, Ter-Ovanesyan, Dmitry, Qian, Jason, Pruitt, Benjamin W, Buchthal, Joanna, Church, George, Kiani, Samira, Hall, Richard N., Beal, Jacob S, Vora, Suhani Deepak, Kowal, Emma J., Ebrahimkhani, Mohammad Reza, Collins, James J., Weiss, Ron
Published 2017

Human Intestinal Tissue with Adult Stem Cell Properties Derived from Pluripotent Stem Cells

by Forster, Ryan, Chiba, Kunitoshi, Schaeffer, Lorian, Regalado, Samuel G, Lai, Christine S., Gao, Qing, Kiani, Samira, Farin, Henner F, Clevers, Hans, Cost, Gregory J., Chan, Andy, Rebar, Edward J, Urnov, Fyodor D, Gregory, Philip D., Jaenisch, Rudolf, Hockemeyer, Dirk, Pachter, Lior 1973-
Published 2015

Highly efficient Cas9-mediated transcriptional programming

by Chavez, Alejandro, Scheiman, Jonathan, Tuttle, Marcelle, Lin, Shuailiang, Kiani, Samira, Ter-Ovanesyan, Dmitry, Davidsohn, Noah, Perrimon, Norbert, Weiss, Ron, Aach, John, Vora, Suhani Deepak, Pruitt, Benjamin W., Iyer, Eswar P. R., Guzman, Christopher D., Wiegand, Daniel J., Braff, Jonathan L., Housden, Benjamin E., Collins, James J., Church, George M.
Published 2015

An enhanced CRISPR repressor for targeted mammalian gene regulation

by Yeo, Nan Cher, Chavez, Alejandro, Lance-Byrne, Alissa, Chan, Yingleong, Menn, David, Milanova, Denitsa, Kuo, Chih-Chung, Guo, Xiaoge, Sharma, Sumana, Tung, Angela, Cecchi, Ryan J., Tuttle, Marcelle, Pradhan, Swechchha, Lim, Elaine T., Davidsohn, Noah, Ebrahimkhani, Mo R., Lewis, Nathan E., Kiani, Samira, Church, George M., Collins, James J.
Published 2019

Genetic engineering of human ES and iPS cells using TALE nucleases

by Hockemeyer, Dirk, Wang, Haoyi, Kiani, Samira, Lai, Christine S., Gao, Qing, Cassady, John P., Cost, Gregory J., Santiago, Yolanda, Miller, Jeffrey C., Zeitler, Bryan, Cherone, Jennifer Michelle, Meng, Xiangdong, Hinkley, Sarah J., Rebar, Edward J., Gregory, Philip D., Urnov, Fyodor D., Jaenisch, Rudolf, Zhang, Lei, Ph. D Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, fl. 2014
Published 2012