CRISPR-based genomic tools for the manipulation of genetically intractable microorganisms

by Chavez, Alejandro, Collins, James J., Shapiro, Rebecca
Published 2018

CRISPR Guide RNA Cloning for Mammalian Systems

by Nageshwaran, Sathiji, Chavez, Alejandro, Cher Yeo, Nan, Guo, Xiaoge, Lance-Byrne, Alissa, Tung, Angela, Collins, James J., Church, George M.
Published 2020

Precise Cas9 targeting enables genomic mutation prevention

by Chavez, Alejandro, Pruitt, Benjamin W., Tuttle, Marcelle, Cecchi, Ryan J., Winston, Jordan, Turczyk, Brian M., Tung, Michael, Collins, James J., Church, George M, Shapiro, Rebecca
Published 2018

Daisy-chain gene drives for the alteration of local populations

by Noble, Charleston, Min, John, Olejarz, Jason, Buchthal, Joanna, Chavez, Alejandro, Smidler, Andrea L., DeBenedictis, Erika A., Church, George M., Nowak, Martin A., Esvelt, Kevin Michael
Published 2020

Enabling multiplexed testing of pooled donor cells through whole-genome sequencing

by Chan, Yingleong, Chan, Ying K, Guo, Xiaoge, Chavez, Alejandro, Lim, Elaine T, Church, George M, Chan, Ying Kai, Goodman, Daniel B., Lim, Elaine T., Church, George M., Goodman, Daniel Bryan
Published 2018

A CRISPR-Cas9-based gene drive platform for genetic interaction analysis in Candida albicans

by Shapiro, Rebecca S., Chavez, Alejandro, Porter, Caroline B. M., Hamblin, Meagan, Kaas, Christian S., DiCarlo, James E., Zeng, Guisheng, Xu, Xiaoli, Revtovich, Alexey V., Kirienko, Natalia V., Wang, Yue, Church, George M., Collins, James J.
Published 2018

Comparison of Cas9 activators in multiple species

by Chavez, Alejandro, Tuttle, Marcelle, Pruitt, Benjamin W, Ewen-Campen, Ben, Chari, Raj, Ter-Ovanesyan, Dmitry, Haque, Sabina J, Cecchi, Ryan J, Kowal, Emma J K, Buchthal, Joanna, Housden, Benjamin E, Perrimon, Norbert, Church, George, Collins, James J.
Published 2017

Cas9 gRNA engineering for genome editing, activation and repression

by Chavez, Alejandro, Tuttle, Marcelle, Chari, Raj, Ter-Ovanesyan, Dmitry, Qian, Jason, Pruitt, Benjamin W, Buchthal, Joanna, Church, George, Kiani, Samira, Hall, Richard N., Beal, Jacob S, Vora, Suhani Deepak, Kowal, Emma J., Ebrahimkhani, Mohammad Reza, Collins, James J., Weiss, Ron
Published 2017

Highly efficient Cas9-mediated transcriptional programming

by Chavez, Alejandro, Scheiman, Jonathan, Tuttle, Marcelle, Lin, Shuailiang, Kiani, Samira, Ter-Ovanesyan, Dmitry, Davidsohn, Noah, Perrimon, Norbert, Weiss, Ron, Aach, John, Vora, Suhani Deepak, Pruitt, Benjamin W., Iyer, Eswar P. R., Guzman, Christopher D., Wiegand, Daniel J., Braff, Jonathan L., Housden, Benjamin E., Collins, James J., Church, George M.
Published 2015

An enhanced CRISPR repressor for targeted mammalian gene regulation

by Yeo, Nan Cher, Chavez, Alejandro, Lance-Byrne, Alissa, Chan, Yingleong, Menn, David, Milanova, Denitsa, Kuo, Chih-Chung, Guo, Xiaoge, Sharma, Sumana, Tung, Angela, Cecchi, Ryan J., Tuttle, Marcelle, Pradhan, Swechchha, Lim, Elaine T., Davidsohn, Noah, Ebrahimkhani, Mo R., Lewis, Nathan E., Kiani, Samira, Church, George M., Collins, James J.
Published 2019