Tissue effect on genetic control of transcript isoform variation.

by Tony Kwan, Elin Grundberg, Vonda Koka, Bing Ge, Kevin C L Lam, Christel Dias, Andreas Kindmark, Hans Mallmin, Osten Ljunggren, Fernando Rivadeneira, Karol Estrada, Joyce B van Meurs, Andre Uitterlinden, Magnus Karlsson, Claes Ohlsson, Dan Mellström, Olle Nilsson, Tomi Pastinen, Jacek Majewski
Published 2009-08-01

An ARHGAP25 variant links aberrant Rac1 function to early‐onset skeletal fragility

by Riikka E. Mäkitie, Petra Henning, Yaming Jiu, Anders Kämpe, Konstantin Kogan, Alice Costantini, Ville‐Valtteri Välimäki, Carolina Medina‐Gomez, Minna Pekkinen, Isidro B. Salusky, Camilla Schalin‐Jäntti, Maria K. Haanpää, Fernando Rivadeneira, John H. Duncan Bassett, Graham R. Williams, Ulf H. Lerner, Renata C. Pereira, Pekka Lappalainen, Outi Mäkitie
Published 2021-07-01

Digital quantification of human eye color highlights genetic association of three new loci.

by Fan Liu, Andreas Wollstein, Pirro G Hysi, Georgina A Ankra-Badu, Timothy D Spector, Daniel Park, Gu Zhu, Mats Larsson, David L Duffy, Grant W Montgomery, David A Mackey, Susan Walsh, Oscar Lao, Albert Hofman, Fernando Rivadeneira, Johannes R Vingerling, André G Uitterlinden, Nicholas G Martin, Christopher J Hammond, Manfred Kayser
Published 2010-05-01

The “GEnomics of Musculo Skeletal Traits TranslatiOnal NEtwork”: Origins, Rationale, Organization, and Prospects

by Fjorda Koromani, Fjorda Koromani, Fjorda Koromani, Nerea Alonso, Ines Alves, Maria Luisa Brandi, Ines Foessl, Melissa M. Formosa, Milana Frenkel Morgenstern, David Karasik, Mikhail Kolev, Outi Makitie, Outi Makitie, Outi Makitie, Evangelia Ntzani, Evangelia Ntzani, Barbara Obermayer Pietsch, Claes Ohlsson, Martina Rauner, Kent Soe, Kent Soe, Kent Soe, Ivan Soldatovic, Anna Teti, Amina Valjevac, Fernando Rivadeneira
Published 2021-08-01

Genome-wide association study for acute otitis media in children identifies FNDC1 as disease contributing gene

by Gijs van Ingen, Jin Li, André Goedegebure, Rahul Pandey, Yun Rose Li, Michael E. March, Vincent W. V. Jaddoe, Marina Bakay, Frank D. Mentch, Kelly Thomas, Zhi Wei, Xiao Chang, Heather S. Hain, André G. Uitterlinden, Henriette A. Moll, Cornelia M. van Duijn, Fernando Rivadeneira, Hein Raat, Robert J. Baatenburg de Jong, Patrick M. Sleiman, Marc P. van der Schroeff, Hakon Hakonarson
Published 2016-09-01

Opportunities and Challenges in Functional Genomics Research in Osteoporosis: Report From a Workshop Held by the Causes Working Group of the Osteoporosis and Bone Research Academy...

by Jonathan H. Tobias, Jonathan H. Tobias, Emma L. Duncan, Erika Kague, Chrissy L. Hammond, Celia L. Gregson, Celia L. Gregson, Duncan Bassett, Graham R. Williams, Josine L. Min, Tom R. Gaunt, David Karasik, Claes Ohlsson, Fernando Rivadeneira, James R. Edwards, Fadil M. Hannan, John P. Kemp, John P. Kemp, Sophie J. Gilbert, Nerea Alonso, Neelam Hassan, Juliet E. Compston, Stuart H. Ralston
Published 2021-02-01

A genome-wide association study of optic disc parameters.

by Wishal D Ramdas, Leonieke M E van Koolwijk, M Kamran Ikram, Nomdo M Jansonius, Paulus T V M de Jong, Arthur A B Bergen, Aaron Isaacs, Najaf Amin, Yurii S Aulchenko, Roger C W Wolfs, Albert Hofman, Fernando Rivadeneira, Ben A Oostra, Andre G Uitterlinden, Pirro Hysi, Christopher J Hammond, Hans G Lemij, Johannes R Vingerling, Caroline C W Klaver, Cornelia M van Duijn
Published 2010-06-01

Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study.

by Vincenzo Forgetta, Julyan Keller-Baruch, Marie Forest, Audrey Durand, Sahir Bhatnagar, John P Kemp, Maria Nethander, Daniel Evans, John A Morris, Douglas P Kiel, Fernando Rivadeneira, Helena Johansson, Nicholas C Harvey, Dan Mellström, Magnus Karlsson, Cyrus Cooper, David M Evans, Robert Clarke, John A Kanis, Eric Orwoll, Eugene V McCloskey, Claes Ohlsson, Joelle Pineau, William D Leslie, Celia M T Greenwood, J Brent Richards
Published 2020-07-01

A genome wide association study links glutamate receptor pathway to sporadic Creutzfeldt-Jakob disease risk.

by Pascual Sanchez-Juan, Matthew T Bishop, Gabor G Kovacs, Miguel Calero, Yurii S Aulchenko, Anna Ladogana, Alison Boyd, Victoria Lewis, Claudia Ponto, Olga Calero, Anna Poleggi, Ángel Carracedo, Sven J van der Lee, Thomas Ströbel, Fernando Rivadeneira, Albert Hofman, Stéphane Haïk, Onofre Combarros, José Berciano, Andre G Uitterlinden, Steven J Collins, Herbert Budka, Jean-Philippe Brandel, Jean Louis Laplanche, Maurizio Pocchiari, Inga Zerr, Richard S G Knight, Robert G Will, Cornelia M van Duijn
Published 2014-01-01

Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus.

by Carolina Medina-Gomez, John P Kemp, Karol Estrada, Joel Eriksson, Jeff Liu, Sjur Reppe, David M Evans, Denise H M Heppe, Liesbeth Vandenput, Lizbeth Herrera, Susan M Ring, Claudia J Kruithof, Nicholas J Timpson, M Carola Zillikens, Ole K Olstad, Hou-Feng Zheng, J Brent Richards, Beate St Pourcain, Albert Hofman, Vincent W V Jaddoe, George Davey Smith, Mattias Lorentzon, Kaare M Gautvik, André G Uitterlinden, Robert Brommage, Claes Ohlsson, Jonathan H Tobias, Fernando Rivadeneira
Published 2012-07-01

The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels.

by Elisabeth M van Leeuwen, Françoise A S Smouter, Tony Kam-Thong, Nazanin Karbalai, Albert V Smith, Tamara B Harris, Lenore J Launer, Colleen M Sitlani, Guo Li, Jennifer A Brody, Joshua C Bis, Charles C White, Alok Jaiswal, Ben A Oostra, Albert Hofman, Fernando Rivadeneira, Andre G Uitterlinden, Eric Boerwinkle, Christie M Ballantyne, Vilmundur Gudnason, Bruce M Psaty, L Adrienne Cupples, Marjo-Riitta Järvelin, Samuli Ripatti, Aaron Isaacs, Bertram Müller-Myhsok, Lennart C Karssen, Cornelia M van Duijn
Published 2014-01-01

Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium.

by Megan L Grove, Bing Yu, Barbara J Cochran, Talin Haritunians, Joshua C Bis, Kent D Taylor, Mark Hansen, Ingrid B Borecki, L Adrienne Cupples, Myriam Fornage, Vilmundur Gudnason, Tamara B Harris, Sekar Kathiresan, Robert Kraaij, Lenore J Launer, Daniel Levy, Yongmei Liu, Thomas Mosley, Gina M Peloso, Bruce M Psaty, Stephen S Rich, Fernando Rivadeneira, David S Siscovick, Albert V Smith, Andre Uitterlinden, Cornelia M van Duijn, James G Wilson, Christopher J O'Donnell, Jerome I Rotter, Eric Boerwinkle
Published 2013-01-01

An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.

by Yi-Hsiang Hsu, M Carola Zillikens, Scott G Wilson, Charles R Farber, Serkalem Demissie, Nicole Soranzo, Estelle N Bianchi, Elin Grundberg, Liming Liang, J Brent Richards, Karol Estrada, Yanhua Zhou, Atila van Nas, Miriam F Moffatt, Guangju Zhai, Albert Hofman, Joyce B van Meurs, Huibert A P Pols, Roger I Price, Olle Nilsson, Tomi Pastinen, L Adrienne Cupples, Aldons J Lusis, Eric E Schadt, Serge Ferrari, André G Uitterlinden, Fernando Rivadeneira, Timothy D Spector, David Karasik, Douglas P Kiel
Published 2010-06-01

Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS.

by Frank P Diekstra, Christiaan G J Saris, Wouter van Rheenen, Lude Franke, Ritsert C Jansen, Michael A van Es, Paul W J van Vught, Hylke M Blauw, Ewout J N Groen, Steve Horvath, Karol Estrada, Fernando Rivadeneira, Albert Hofman, Andre G Uitterlinden, Wim Robberecht, Peter M Andersen, Judith Melki, Vincent Meininger, Orla Hardiman, John E Landers, Robert H Brown, Aleksey Shatunov, Christopher E Shaw, P Nigel Leigh, Ammar Al-Chalabi, Roel A Ophoff, Leonard H van den Berg, Jan H Veldink
Published 2012-01-01

A genome-wide association study identifies five loci influencing facial morphology in Europeans.

by Fan Liu, Fedde van der Lijn, Claudia Schurmann, Gu Zhu, M Mallar Chakravarty, Pirro G Hysi, Andreas Wollstein, Oscar Lao, Marleen de Bruijne, M Arfan Ikram, Aad van der Lugt, Fernando Rivadeneira, André G Uitterlinden, Albert Hofman, Wiro J Niessen, Georg Homuth, Greig de Zubicaray, Katie L McMahon, Paul M Thompson, Amro Daboul, Ralf Puls, Katrin Hegenscheid, Liisa Bevan, Zdenka Pausova, Sarah E Medland, Grant W Montgomery, Margaret J Wright, Carol Wicking, Stefan Boehringer, Timothy D Spector, Tomáš Paus, Nicholas G Martin, Reiner Biffar, Manfred Kayser
Published 2012-09-01

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

by Simon Haworth, Chin Yang Shapland, Caroline Hayward, Bram P. Prins, Janine F. Felix, Carolina Medina-Gomez, Fernando Rivadeneira, Carol Wang, Tarunveer S. Ahluwalia, Martine Vrijheid, Mònica Guxens, Jordi Sunyer, Ioanna Tachmazidou, Klaudia Walter, Valentina Iotchkova, Andrew Jackson, Louise Cleal, Jennifer Huffmann, Josine L. Min, Lærke Sass, Paul R. H. J. Timmers, UK10K consortium, George Davey Smith, Simon E. Fisher, James F. Wilson, Tim J. Cole, Dietmar Fernandez-Orth, Klaus Bønnelykke, Hans Bisgaard, Craig E. Pennell, Vincent W. V. Jaddoe, George Dedoussis, Nicholas Timpson, Eleftheria Zeggini, Veronique Vitart, Beate St Pourcain
Published 2019-01-01

Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: the GENOMOS study.

by Stuart H Ralston, André G Uitterlinden, Maria Luisa Brandi, Susana Balcells, Bente L Langdahl, Paul Lips, Roman Lorenc, Barbara Obermayer-Pietsch, Serena Scollen, Mariona Bustamante, Lise Bjerre Husted, Alisoun H Carey, Adolfo Diez-Perez, Alison M Dunning, Alberto Falchetti, Elzbieta Karczmarewicz, Marcin Kruk, Johannes P T M van Leeuwen, Joyce B J van Meurs, Jon Mangion, Fiona E A McGuigan, Leonardo Mellibovsky, Francesca del Monte, Huibert A P Pols, Jonathan Reeve, David M Reid, Wilfried Renner, Fernando Rivadeneira, Natasja M van Schoor, Rachael E Sherlock, John P A Ioannidis, GENOMOS Investigators
Published 2006-04-01

Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

by Carolina Medina-Gomez, John P. Kemp, Niki L. Dimou, Eskil Kreiner, Alessandra Chesi, Babette S. Zemel, Klaus Bønnelykke, Cindy G. Boer, Tarunveer S. Ahluwalia, Hans Bisgaard, Evangelos Evangelou, Denise H. M. Heppe, Lynda F. Bonewald, Jeffrey P. Gorski, Mohsen Ghanbari, Serkalem Demissie, Gustavo Duque, Matthew T. Maurano, Douglas P. Kiel, Yi-Hsiang Hsu, Bram C.J. van der Eerden, Cheryl Ackert-Bicknell, Sjur Reppe, Kaare M. Gautvik, Truls Raastad, David Karasik, Jeroen van de Peppel, Vincent W. V. Jaddoe, André G. Uitterlinden, Jonathan H. Tobias, Struan F.A. Grant, Pantelis G. Bagos, David M. Evans, Fernando Rivadeneira
Published 2017-07-01

Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD.

by Carsten A Böger, Mathias Gorski, Man Li, Michael M Hoffmann, Chunmei Huang, Qiong Yang, Alexander Teumer, Vera Krane, Conall M O'Seaghdha, Zoltán Kutalik, H-Erich Wichmann, Thomas Haak, Eva Boes, Stefan Coassin, Josef Coresh, Barbara Kollerits, Margot Haun, Bernhard Paulweber, Anna Köttgen, Guo Li, Michael G Shlipak, Neil Powe, Shih-Jen Hwang, Abbas Dehghan, Fernando Rivadeneira, André Uitterlinden, Albert Hofman, Jacques S Beckmann, Bernhard K Krämer, Jacqueline Witteman, Murielle Bochud, David Siscovick, Rainer Rettig, Florian Kronenberg, Christoph Wanner, Ravi I Thadhani, Iris M Heid, Caroline S Fox, W H Kao, CKDGen Consortium
Published 2011-09-01

Correction: Large-Scale Evidence for the Effect of the Sp1 Polymorphism on Osteoporosis Outcomes: The GENOMOS Study.

by Stuart H Ralston, André G Uitterlinden, Maria Luisa Brandi, Susana Balcells, Bente L Langdahl, Paul Lips, Roman Lorenc, Barbara Obermayer-Pietsch, Serena Scollen, Mariona Bustamante, Lise Bjerre Husted, Alisoun H Carey, Adolfo Diez-Perez, Alison M Dunning, Alberto Falchetti, Elzbieta Karczmarewicz, Marcin Kruk, Johannes P. T. M van Leeuwen, Joyce B. J van Meurs, Jon Mangion, Fiona E. A McGuigan, Leonardo Mellibovsky, Francesca del Monte, Huibert A. P Pols, Jonathan Reeve, David M Reid, Wilfried Renner, Fernando Rivadeneira, Natasja M van Schoor, Rachael E Sherlock, John P. A Ioannidis
Published 2006-05-01