Development of anti-thrombotic vaccine against human S100A9 in rhesus monkey

by Munehisa Shimamura, Koichi Kaikita, Hironori Nakagami, Tomohiro Kawano, Nan Ju, Hiroki Hayashi, Ryo Nakamaru, Shota Yoshida, Tsutomu Sasaki, Hideki Mochizuki, Kenichi Tsujita, Ryuichi Morishita
Published 2021-06-01

Beneficial effects of fingolimod in MS patients with high serum Sema4A levels.

by Toru Koda, Akiko Namba, Yuji Nakatsuji, Masaaki Niino, Yusei Miyazaki, Tomoyuki Sugimoto, Makoto Kinoshita, Kazushiro Takata, Kazuya Yamashita, Mikito Shimizu, Toshiyuki Fukazawa, Atsushi Kumanogoh, Hideki Mochizuki, Tatsusada Okuno
Published 2018-01-01

Next-generation sequencing identifies contribution of both class I and II HLA genes on susceptibility of multiple sclerosis in Japanese

by Kotaro Ogawa, Tatsusada Okuno, Kazuyoshi Hosomichi, Akiko Hosokawa, Jun Hirata, Ken Suzuki, Saori Sakaue, Makoto Kinoshita, Yoshihiro Asano, Katsuichi Miyamoto, Ituro Inoue, Susumu Kusunoki, Yukinori Okada, Hideki Mochizuki
Published 2019-08-01

Human Genomic Safe Harbors and the Suicide Gene‐Based Safeguard System for iPSC‐Based Cell Therapy

by Yasuyoshi Kimura, Tomoko Shofuda, Yuichiro Higuchi, Ippei Nagamori, Masaaki Oda, Masayuki Nakamori, Masafumi Onodera, Daisuke Kanematsu, Atsuyo Yamamoto, Asako Katsuma, Hiroshi Suemizu, Toru Nakano, Yonehiro Kanemura, Hideki Mochizuki
Published 2019-07-01

Cerebrospinal fluid mitochondrial DNA in neuromyelitis optica spectrum disorder

by Kazuya Yamashita, Makoto Kinoshita, Katsuichi Miyamoto, Akiko Namba, Mikito Shimizu, Toru Koda, Tomoyuki Sugimoto, Yuki Mori, Yoshichika Yoshioka, Yuji Nakatsuji, Atsushi Kumanogoh, Susumu Kusunoki, Hideki Mochizuki, Tatsusada Okuno
Published 2018-04-01

Sema4A is implicated in the acceleration of Th17 cell-mediated neuroinflammation in the effector phase

by Toru Koda, Akiko Namba, Makoto Kinoshita, Yuji Nakatsuji, Tomoyuki Sugimoto, Kaori Sakakibara, Satoru Tada, Mikito Shimizu, Kazuya Yamashita, Kazushiro Takata, Teruyuki Ishikura, Syo Murata, Shohei Beppu, Atsushi Kumanogoh, Hideki Mochizuki, Tatsusada Okuno
Published 2020-03-01

Breakdown of supersaturation barrier links protein folding to amyloid formation

by Masahiro Noji, Tatsushi Samejima, Keiichi Yamaguchi, Masatomo So, Keisuke Yuzu, Eri Chatani, Yoko Akazawa-Ogawa, Yoshihisa Hagihara, Yasushi Kawata, Kensuke Ikenaka, Hideki Mochizuki, József Kardos, Daniel E. Otzen, Vittorio Bellotti, Johannes Buchner, Yuji Goto
Published 2021-01-01

Febuxostat ameliorates secondary progressive experimental autoimmune encephalomyelitis by restoring mitochondrial energy production in a GOT2-dependent manner.

by Josephe A Honorat, Yuji Nakatsuji, Mikito Shimizu, Makoto Kinoshita, Hisae Sumi-Akamaru, Tsutomu Sasaki, Kazushiro Takata, Toru Koda, Akiko Namba, Kazuya Yamashita, Eri Sanda, Manabu Sakaguchi, Atsushi Kumanogoh, Takashi Shirakura, Mizuho Tamura, Saburo Sakoda, Hideki Mochizuki, Tatsusada Okuno
Published 2017-01-01

Anti-AQP4 autoantibodies promote ATP release from astrocytes and induce mechanical pain in rats

by Teruyuki Ishikura, Makoto Kinoshita, Mikito Shimizu, Yoshiaki Yasumizu, Daisuke Motooka, Daisuke Okuzaki, Kazuya Yamashita, Hisashi Murata, Shohei Beppu, Toru Koda, Satoru Tada, Naoyuki Shiraishi, Yasuko Sugiyama, Katsuichi Miyamoto, Susumu Kusunoki, Tomoyuki Sugimoto, Atsushi Kumanogoh, Tatsusada Okuno, Hideki Mochizuki
Published 2021-08-01

Futile complete recanalization: patients characteristics and its time course

by Takaya Kitano, Kenichi Todo, Shinichi Yoshimura, Kazutaka Uchida, Hiroshi Yamagami, Nobuyuki Sakai, Manabu Sakaguchi, Hajime Nakamura, Haruhiko Kishima, Hideki Mochizuki, Masayuki Ezura, Yasushi Okada, Kazuo Kitagawa, Kazumi Kimura, Makoto Sasaki, Norio Tanahashi, Kazunori Toyoda, Eisuke Furui, Yuji Matsumaru, Kazuo Minematsu, Takeshi Morimoto
Published 2020-03-01

A Metagenome-Wide Association Study of Gut Microbiome in Patients With Multiple Sclerosis Revealed Novel Disease Pathology

by Toshihiro Kishikawa, Toshihiro Kishikawa, Kotaro Ogawa, Kotaro Ogawa, Daisuke Motooka, Akiko Hosokawa, Akiko Hosokawa, Makoto Kinoshita, Ken Suzuki, Kenichi Yamamoto, Kenichi Yamamoto, Tatsuo Masuda, Yuki Matsumoto, Takuro Nii, Takuro Nii, Yuichi Maeda, Yuichi Maeda, Shota Nakamura, Shota Nakamura, Hidenori Inohara, Hideki Mochizuki, Tatsusada Okuno, Yukinori Okada, Yukinori Okada, Yukinori Okada
Published 2020-12-01

Suppression of autophagic activity by Rubicon is a signature of aging

by Shuhei Nakamura, Masaki Oba, Mari Suzuki, Atsushi Takahashi, Tadashi Yamamuro, Mari Fujiwara, Kensuke Ikenaka, Satoshi Minami, Namine Tabata, Kenichi Yamamoto, Sayaka Kubo, Ayaka Tokumura, Kanako Akamatsu, Yumi Miyazaki, Tsuyoshi Kawabata, Maho Hamasaki, Koji Fukui, Kazunori Sango, Yoshihisa Watanabe, Yoshitsugu Takabatake, Tomoya S. Kitajima, Yukinori Okada, Hideki Mochizuki, Yoshitaka Isaka, Adam Antebi, Tamotsu Yoshimori
Published 2019-02-01

Author Correction: Time–outcome relationship in acute large-vessel occlusion exists across all ages: subanalysis of RESCUE-Japan Registry 2

by Kenichi Todo, Shinichi Yoshimura, Kazutaka Uchida, Hiroshi Yamagami, Nobuyuki Sakai, Haruhiko Kishima, Hideki Mochizuki, Masayuki Ezura, Yasushi Okada, Kazuo Kitagawa, Kazumi Kimura, Makoto Sasaki, Norio Tanahashi, Kazunori Toyoda, Eisuke Furui, Yuji Matsumaru, Kazuo Minematsu, Takaya Kitano, Shuhei Okazaki, Tsutomu Sasaki, Manabu Sakaguchi, Masatoshi Takagaki, Takeo Nishida, Hajime Nakamura, Takeshi Morimoto, RESCUE-Japan Registry 2 Investigators
Published 2021-09-01

Time–outcome relationship in acute large-vessel occlusion exists across all ages: subanalysis of RESCUE-Japan Registry 2

by Kenichi Todo, Shinichi Yoshimura, Kazutaka Uchida, Hiroshi Yamagami, Nobuyuki Sakai, Haruhiko Kishima, Hideki Mochizuki, Masayuki Ezura, Yasushi Okada, Kazuo Kitagawa, Kazumi Kimura, Makoto Sasaki, Norio Tanahashi, Kazunori Toyoda, Eisuke Furui, Yuji Matsumaru, Kazuo Minematsu, Takaya Kitano, Shuhei Okazaki, Tsutomu Sasaki, Manabu Sakaguchi, Masatoshi Takagaki, Takeo Nishida, Hajime Nakamura, Takeshi Morimoto, RESCUE-Japan Registry 2 Investigators
Published 2021-06-01

Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy

by Fernande Freyermuth, Frédérique Rau, Yosuke Kokunai, Thomas Linke, Chantal Sellier, Masayuki Nakamori, Yoshihiro Kino, Ludovic Arandel, Arnaud Jollet, Christelle Thibault, Muriel Philipps, Serge Vicaire, Bernard Jost, Bjarne Udd, John W. Day, Denis Duboc, Karim Wahbi, Tsuyoshi Matsumura, Harutoshi Fujimura, Hideki Mochizuki, François Deryckere, Takashi Kimura, Nobuyuki Nukina, Shoichi Ishiura, Vincent Lacroix, Amandine Campan-Fournier, Vincent Navratil, Emilie Chautard, Didier Auboeuf, Minoru Horie, Keiji Imoto, Kuang-Yung Lee, Maurice S. Swanson, Adolfo Lopez de Munain, Shin Inada, Hideki Itoh, Kazuo Nakazawa, Takashi Ashihara, Eric Wang, Thomas Zimmer, Denis Furling, Masanori P. Takahashi, Nicolas Charlet-Berguerand
Published 2016-04-01

Genetic determinants of risk in autoimmune pulmonary alveolar proteinosis

by Saori Sakaue, Etsuro Yamaguchi, Yoshikazu Inoue, Meiko Takahashi, Jun Hirata, Ken Suzuki, Satoru Ito, Toru Arai, Masaki Hirose, Yoshinori Tanino, Takefumi Nikaido, Toshio Ichiwata, Shinya Ohkouchi, Taizou Hirano, Toshinori Takada, Satoru Miyawaki, Shogo Dofuku, Yuichi Maeda, Takuro Nii, Toshihiro Kishikawa, Kotaro Ogawa, Tatsuo Masuda, Kenichi Yamamoto, Kyuto Sonehara, Ryushi Tazawa, Konosuke Morimoto, Masahiro Takaki, Satoshi Konno, Masaru Suzuki, Keisuke Tomii, Atsushi Nakagawa, Tomohiro Handa, Kiminobu Tanizawa, Haruyuki Ishii, Manabu Ishida, Toshiyuki Kato, Naoya Takeda, Koshi Yokomura, Takashi Matsui, Masaki Watanabe, Hiromasa Inoue, Kazuyoshi Imaizumi, Yasuhiro Goto, Hiroshi Kida, Tomoyuki Fujisawa, Takafumi Suda, Takashi Yamada, Yasuomi Satake, Hidenori Ibata, Nobuyuki Hizawa, Hideki Mochizuki, Atsushi Kumanogoh, Fumihiko Matsuda, Koh Nakata, Tomomitsu Hirota, Mayumi Tamari, Yukinori Okada
Published 2021-02-01