Comparative Transcriptomics Analyses in Livers of Mice, Humans, and Humanized Mice Define Human-Specific Gene Networks

by Chengfei Jiang, Ping Li, Xiangbo Ruan, Yonghe Ma, Kenji Kawai, Hiroshi Suemizu, Haiming Cao
Published 2020-11-01

Whole-exome sequencing of 79 xenografts as a potential approach for the identification of genetic variants associated with sensitivity to cytotoxic anticancer drugs.

by Chihiro Udagawa, Yasushi Sasaki, Yasuhiro Tanizawa, Hiroshi Suemizu, Yasuyuki Ohnishi, Yasukazu Nakamura, Takashi Tokino, Hitoshi Zembutsu
Published 2020-01-01

A versatile technique for the in vivo imaging of human tumor xenografts using near-infrared fluorochrome-conjugated macromolecule probes.

by Hiroshi Suemizu, Kenji Kawai, Yuichiro Higuchi, Haruo Hashimoto, Tomoyuki Ogura, Toshio Itoh, Erika Sasaki, Masato Nakamura
Published 2013-01-01

Generation of Human Immunosuppressive Myeloid Cell Populations in Human Interleukin-6 Transgenic NOG Mice

by Asami Hanazawa, Ryoji Ito, Ikumi Katano, Kenji Kawai, Motohito Goto, Hiroshi Suemizu, Yutaka Kawakami, Mamoru Ito, Takeshi Takahashi
Published 2018-02-01

The adult livers of immunodeficient mice support human hematopoiesis: evidence for a hepatic mast cell population that develops early in human ontogeny.

by Marcus O Muench, Ashley I Beyer, Marina E Fomin, Rahul Thakker, Usha S Mulvaney, Masato Nakamura, Hiroshi Suemizu, Alicia Bárcena
Published 2014-01-01

Human iPS Cell–based Liver-like Tissue Engineering at Extrahepatic Sites in Mice as a New Cell Therapy for Hemophilia B

by Ryota Okamoto, Kazuo Takayama, Naoki Akita, Yasuhito Nagamoto, Daiki Hosokawa, Shunsuke Iizuka, Fuminori Sakurai, Hiroshi Suemizu, Kazuo Ohashi, Hiroyuki Mizuguchi
Published 2018-02-01

Feeder-free generation and long-term culture of human induced pluripotent stem cells using pericellular matrix of decidua derived mesenchymal cells.

by Hayato Fukusumi, Tomoko Shofuda, Daisuke Kanematsu, Atsuyo Yamamoto, Hiroshi Suemizu, Masato Nakamura, Mami Yamasaki, Masatoshi Ohgushi, Yoshiki Sasai, Yonehiro Kanemura
Published 2013-01-01

Long-term maintenance of peripheral blood derived human NK cells in a novel human IL-15- transgenic NOG mouse

by Ikumi Katano, Chiyoko Nishime, Ryoji Ito, Tsutomu Kamisako, Takuma Mizusawa, Yuyo Ka, Tomoyuki Ogura, Hiroshi Suemizu, Yutaka Kawakami, Mamoru Ito, Takeshi Takahashi
Published 2017-12-01

Generation of Induced Pluripotent Stem Cells and Neural Stem/Progenitor Cells from Newborns with Spina Bifida Aperta

by Yohei Bamba, Masahiro Nonaka, Natsu Sasaki, Tomoko Shofuda, Daisuke Kanematsu, Hiroshi Suemizu, Yuichiro Higuchi, Ritsuko K. Pooh, Yonehiro Kanemura, Hideyuki Okano, Mami Yamasaki
Published 2017-12-01

Human hepatocyte depletion in the presence of HIV-1 infection in dual reconstituted humanized mice

by Raghubendra Singh Dagur, Weimin Wang, Yan Cheng, Edward Makarov, Murali Ganesan, Hiroshi Suemizu, Catherine L. Gebhart, Santhi Gorantla, Natalia Osna, Larisa Y. Poluektova
Published 2018-02-01

Establishment of novel common marmoset embryonic stem cell lines under various conditions

by Keiko Kishimoto, Akiko Shimada, Haruka Shinohara, Tsukasa Takahashi, Yuko Yamada, Yuichiro Higuchi, Nao Yoneda, Hiroshi Suemizu, Kenji Kawai, Yoko Kurotaki, Kisaburo Hanazawa, Yasuhiro Takashima, Erika Sasaki
Published 2021-05-01

Birth of healthy offspring following ICSI in in vitro-matured common marmoset (Callithrix jacchus) oocytes.

by Tsukasa Takahashi, Kisaburo Hanazawa, Takashi Inoue, Kenya Sato, Ayako Sedohara, Junko Okahara, Hiroshi Suemizu, Chie Yagihashi, Masafumi Yamamoto, Tomoo Eto, Yusuke Konno, Hideyuki Okano, Makoto Suematsu, Erika Sasaki
Published 2014-01-01

Identification of an astrovirus commonly infecting laboratory mice in the US and Japan.

by Terry Fei Fan Ng, Nikola O Kondov, Nobuhito Hayashimoto, Ritsuki Uchida, Yunhee Cha, Ashley I Beyer, Walt Wong, Patricia A Pesavento, Hiroshi Suemizu, Marcus O Muench, Eric Delwart
Published 2013-01-01

Human Genomic Safe Harbors and the Suicide Gene‐Based Safeguard System for iPSC‐Based Cell Therapy

by Yasuyoshi Kimura, Tomoko Shofuda, Yuichiro Higuchi, Ippei Nagamori, Masaaki Oda, Masayuki Nakamori, Masafumi Onodera, Daisuke Kanematsu, Atsuyo Yamamoto, Asako Katsuma, Hiroshi Suemizu, Toru Nakano, Yonehiro Kanemura, Hideki Mochizuki
Published 2019-07-01

The Hepatitis B Virus Genotype Affects the Persistence of Viral Replication in Immunodeficient NOG Mice.

by Yoshinobu Yokoyama, Takuya Miyagi, Hayato Hikita, Teppei Yoshioka, Kaori Mukai, Takatoshi Nawa, Ryotaro Sakamori, Kazuyoshi Ohkawa, Naoki Hiramatsu, Takeshi Takahashi, Hiroshi Suemizu, Akihide Ryo, Tomohide Tatsumi, Tetsuo Takehara
Published 2015-01-01

In vivo functional analysis of non-conserved human lncRNAs associated with cardiometabolic traits

by Xiangbo Ruan, Ping Li, Yi Chen, Yu Shi, Mehdi Pirooznia, Fayaz Seifuddin, Hiroshi Suemizu, Yasuyuki Ohnishi, Nao Yoneda, Megumi Nishiwaki, James Shepherdson, Abhilash Suresh, Komudi Singh, Yonghe Ma, Cheng-fei Jiang, Haiming Cao
Published 2020-01-01