A RHO Small GTPase Regulator ABR Secures Mitotic Fidelity in Human Embryonic Stem Cells

by Masatoshi Ohgushi, Maki Minaguchi, Mototsugu Eiraku, Yoshiki Sasai
Published 2017-07-01

Self-patterning of rostral-caudal neuroectoderm requires dual role of Fgf signaling for localized Wnt antagonism

by Nozomu Takata, Eriko Sakakura, Mototsugu Eiraku, Takeya Kasukawa, Yoshiki Sasai
Published 2017-11-01

Self-Organization of Polarized Cerebellar Tissue in 3D Culture of Human Pluripotent Stem Cells

by Keiko Muguruma, Ayaka Nishiyama, Hideshi Kawakami, Kouichi Hashimoto, Yoshiki Sasai
Published 2015-02-01

Vulnerability of Purkinje Cells Generated from Spinocerebellar Ataxia Type 6 Patient-Derived iPSCs

by Yoshihito Ishida, Hideshi Kawakami, Hiroyuki Kitajima, Ayaka Nishiyama, Yoshiki Sasai, Haruhisa Inoue, Keiko Muguruma
Published 2016-11-01

Vulnerability of Purkinje Cells Generated from Spinocerebellar Ataxia Type 6 Patient-Derived iPSCs

by Yoshihito Ishida, Hideshi Kawakami, Hiroyuki Kitajima, Ayaka Nishiyama, Yoshiki Sasai, Haruhisa Inoue, Keiko Muguruma
Published 2017-01-01

One-Step Induction of Neurons from Mouse Embryonic Stem Cells in Serum-Free Media Containing Vitamin B and Heparin

by Hironori Yamazoe, Masato Kobori, Yoshinobu Murakami, Keiichi Yano, Mitsuo Satoh, Kenji Mizuseki, Yoshiki Sasai, Hiroo Iwata
Published 2006-02-01

Transplantation of Embryonic and Induced Pluripotent Stem Cell-Derived 3D Retinal Sheets into Retinal Degenerative Mice

by Juthaporn Assawachananont, Michiko Mandai, Satoshi Okamoto, Chikako Yamada, Mototsugu Eiraku, Shigenobu Yonemura, Yoshiki Sasai, Masayo Takahashi
Published 2014-05-01

Functional anterior pituitary generated in self-organizing culture of human embryonic stem cells

by Chikafumi Ozone, Hidetaka Suga, Mototsugu Eiraku, Taisuke Kadoshima, Shigenobu Yonemura, Nozomu Takata, Yutaka Oiso, Takashi Tsuji, Yoshiki Sasai
Published 2016-01-01

Cultivation of corneal endothelial cells on a pericellular matrix prepared from human decidua-derived mesenchymal cells.

by Ryohei Numata, Naoki Okumura, Makiko Nakahara, Morio Ueno, Shigeru Kinoshita, Daisuke Kanematsu, Yonehiro Kanemura, Yoshiki Sasai, Noriko Koizumi
Published 2014-01-01

Robust formation and maintenance of continuous stratified cortical neuroepithelium by laminin-containing matrix in mouse ES cell culture.

by Makoto Nasu, Nozomu Takata, Teruko Danjo, Hideya Sakaguchi, Taisuke Kadoshima, Sugiko Futaki, Kiyotoshi Sekiguchi, Mototsugu Eiraku, Yoshiki Sasai
Published 2012-01-01

Feeder-free generation and long-term culture of human induced pluripotent stem cells using pericellular matrix of decidua derived mesenchymal cells.

by Hayato Fukusumi, Tomoko Shofuda, Daisuke Kanematsu, Atsuyo Yamamoto, Hiroshi Suemizu, Masato Nakamura, Mami Yamasaki, Masatoshi Ohgushi, Yoshiki Sasai, Yonehiro Kanemura
Published 2013-01-01

FGFR1-Frs2/3 signalling maintains sensory progenitors during inner ear hair cell formation.

by Kazuya Ono, Tomoko Kita, Shigeru Sato, Paul O'Neill, Siu-Shan Mak, Marie Paschaki, Masataka Ito, Noriko Gotoh, Kiyoshi Kawakami, Yoshiki Sasai, Raj K Ladher
Published 2014-01-01

An Eye Organoid Approach Identifies Six3 Suppression of R-spondin 2 as a Critical Step in Mouse Neuroretina Differentiation

by Nozomu Takata, Deepti Abbey, Luciano Fiore, Sandra Acosta, Ruopeng Feng, Hyea Jin Gil, Alfonso Lavado, Xin Geng, Ashley Interiano, Geoffrey Neale, Mototsugu Eiraku, Yoshiki Sasai, Guillermo Oliver
Published 2017-11-01

Use of "MGE enhancers" for labeling and selection of embryonic stem cell-derived medial ganglionic eminence (MGE) progenitors and neurons.

by Ying-Jiun J Chen, Daniel Vogt, Yanling Wang, Axel Visel, Shanni N Silberberg, Cory R Nicholas, Teruko Danjo, Joshua L Pollack, Len A Pennacchio, Stewart Anderson, Yoshiki Sasai, Scott C Baraban, Arnold R Kriegstein, Arturo Alvarez-Buylla, John L R Rubenstein
Published 2013-01-01