Nanog induces hyperplasia without initiating tumors

by Gerrit Fischedick, Guangming Wu, Kenjiro Adachi, Marcos J. Araúzo-Bravo, Boris Greber, Martina Radstaak, Gabriele Köhler, Natalia Tapia, Roberto Iacone, Konstantinos Anastassiadis, Hans R. Schöler, Holm Zaehres
Published 2014-09-01

DNA methylation regulates discrimination of enhancers from promoters through a H3K4me1-H3K4me3 seesaw mechanism

by Ali Sharifi-Zarchi, Daniela Gerovska, Kenjiro Adachi, Mehdi Totonchi, Hamid Pezeshk, Ryan J. Taft, Hans R. Schöler, Hamidreza Chitsaz, Mehdi Sadeghi, Hossein Baharvand, Marcos J. Araúzo-Bravo
Published 2017-12-01

Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model

by Hyunah Lee, Hye Yeong Lee, Byeong Eun Lee, Daniela Gerovska, Soo Yong Park, Holm Zaehres, Marcos J Araúzo-Bravo, Jae-Ick Kim, Yoon Ha, Hans R Schöler, Jeong Beom Kim
Published 2020-06-01

Comparative transcriptome analysis in induced neural stem cells reveals defined neural cell identities in vitro and after transplantation into the adult rodent brain

by Anna-Lena Hallmann, Marcos J. Araúzo-Bravo, Christina Zerfass, Volker Senner, Marc Ehrlich, Olympia E. Psathaki, Dong Wook Han, Natalia Tapia, Holm Zaehres, Hans R. Schöler, Tanja Kuhlmann, Gunnar Hargus
Published 2016-05-01

An Integrative Omics Approach Reveals Involvement of <i>BRCA1</i> in Hepatic Metastatic Progression of Colorectal Cancer

by Daniela Gerovska, Gorka Larrinaga, Jon Danel Solano-Iturria, Joana Márquez, Patricia García Gallastegi, Abdel-Majid Khatib, Gereon Poschmann, Kai Stühler, María Armesto, Charles H. Lawrie, Iker Badiola, Marcos J. Araúzo-Bravo
Published 2020-08-01

Discovery and Proof-of-Concept Study of Nuclease Activity as a Novel Biomarker for Breast Cancer Tumors

by Luiza I. Hernandez, Marcos J. Araúzo-Bravo, Daniela Gerovska, Ricardo Rezola Solaun, Isabel Machado, Alien Balian, Juliana Botero, Tania Jiménez, Olaia Zuriarrain Bergara, Lide Larburu Gurruchaga, Ander Urruticoechea, Frank J. Hernandez
Published 2021-01-01

Blockage of the Epithelial-to-Mesenchymal Transition Is Required for Embryonic Stem Cell Derivation

by Mehdi Totonchi, Seyedeh-Nafiseh Hassani, Ali Sharifi-Zarchi, Natalia Tapia, Kenjiro Adachi, Julia Arand, Boris Greber, Davood Sabour, Marcos J. Araúzo-Bravo, Jörn Walter, Mohammad Pakzad, Hamid Gourabi, Hans R. Schöler, Hossein Baharvand
Published 2017-10-01

Oct4 and Hnf4α-induced hepatic stem cells ameliorate chronic liver injury in liver fibrosis model.

by Myung Rae Park, Man Sze Wong, Marcos J Araúzo-Bravo, Hyunah Lee, Donggyu Nam, Soo Yong Park, Hong Dae Seo, Sang Min Lee, Hans Florian Zeilhofer, Holm Zaehres, Hans R Schöler, Jeong Beom Kim
Published 2019-01-01

GAA Deficiency in Pompe Disease Is Alleviated by Exon Inclusion in iPSC-Derived Skeletal Muscle Cells

by Erik van der Wal, Atze J. Bergsma, Tom J.M. van Gestel, Stijn L.M. in ‘t Groen, Holm Zaehres, Marcos J. Araúzo-Bravo, Hans R. Schöler, Ans T. van der Ploeg, W.W.M. Pim Pijnappel
Published 2017-06-01

Germ cell nuclear factor regulates gametogenesis in developing gonads.

by Davood Sabour, Xueping Xu, Arthur C K Chung, Damien Le Menuet, Kinarm Ko, Natalia Tapia, Marcos J Araúzo-Bravo, Luca Gentile, Boris Greber, Karin Hübner, Vittorio Sebastiano, Guangming Wu, Hans R Schöler, Austin J Cooney
Published 2014-01-01

Aberrant methylated key genes of methyl group metabolism within the molecular etiology of urothelial carcinogenesis

by Lars Erichsen, Foued Ghanjati, Agnes Beermann, Cedric Poyet, Thomas Hermanns, Wolfgang A. Schulz, Hans-Helge Seifert, Peter J. Wild, Lorenz Buser, Alexander Kröning, Stefan Braunstein, Martin Anlauf, Silvia Jankowiak, Mohamed Hassan, Marcelo L. Bendhack, Marcos J. Araúzo-Bravo, Simeon Santourlidis
Published 2018-02-01

PR-LncRNA signature regulates glioma cell activity through expression of SOX factors

by Sergio Torres-Bayona, Paula Aldaz, Jaione Auzmendi-Iriarte, Ander Saenz-Antoñanzas, Idoia Garcia, Mariano Arrazola, Daniela Gerovska, Jose Undabeitia, Arrate Querejeta, Larraitz Egaña, Jorge Villanúa, Irune Ruiz, Cristina Sarasqueta, Enrique Urculo, Marcos J. Araúzo-Bravo, Maite Huarte, Nicolas Samprón, Ander Matheu
Published 2018-08-01

Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein

by Marc Ehrlich, Anna-Lena Hallmann, Peter Reinhardt, Marcos J. Araúzo-Bravo, Sabrina Korr, Albrecht Röpke, Olympia E. Psathaki, Petra Ehling, Sven G. Meuth, Adrian L. Oblak, Jill R. Murrell, Bernardino Ghetti, Holm Zaehres, Hans R. Schöler, Jared Sterneckert, Tanja Kuhlmann, Gunnar Hargus
Published 2015-07-01

Origin-Dependent Neural Cell Identities in Differentiated Human iPSCs In Vitro and after Transplantation into the Mouse Brain

by Gunnar Hargus, Marc Ehrlich, Marcos J. Araúzo-Bravo, Kathrin Hemmer, Anna-Lena Hallmann, Peter Reinhardt, Kee-Pyo Kim, Kenjiro Adachi, Simeon Santourlidis, Foued Ghanjati, Mareike Fauser, Christiana Ossig, Alexander Storch, Jeong Beom Kim, Jens C. Schwamborn, Jared Sterneckert, Hans R. Schöler, Tanja Kuhlmann, Holm Zaehres
Published 2014-09-01

Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs

by Damir Jacob Illich, Miao Zhang, Andrei Ursu, Rodrigo Osorno, Kee-Pyo Kim, Juyong Yoon, Marcos J. Araúzo-Bravo, Guangming Wu, Daniel Esch, Davood Sabour, Douglas Colby, Kathrin S. Grassme, Jiayu Chen, Boris Greber, Susanne Höing, Wiebke Herzog, Slava Ziegler, Ian Chambers, Shaorong Gao, Herbert Waldmann, Hans R. Schöler
Published 2016-04-01

Identification and Characterization of the Dermal Panniculus Carnosus Muscle Stem Cells

by Neia Naldaiz-Gastesi, María Goicoechea, Sonia Alonso-Martín, Ana Aiastui, Macarena López-Mayorga, Paula García-Belda, Jaione Lacalle, Carlos San José, Marcos J. Araúzo-Bravo, Lidwine Trouilh, Véronique Anton-Leberre, Diego Herrero, Ander Matheu, Antonio Bernad, José Manuel García-Verdugo, Jaime J. Carvajal, Frédéric Relaix, Adolfo Lopez de Munain, Patricia García-Parra, Ander Izeta
Published 2016-09-01

Signal Integration and Transcriptional Regulation of the Inflammatory Response Mediated by the GM-/M-CSF Signaling Axis in Human Monocytes

by Ramon M. Rodriguez, Beatriz Suarez-Alvarez, Jose L. Lavín, Alex M. Ascensión, Monika Gonzalez, Juan J. Lozano, Aroa B. Raneros, Paula D. Bulnes, Jose R. Vidal-Castiñeira, Covadonga Huidobro, Cristina Martin-Martin, Ana B. Sanz, Marta Ruiz-Ortega, Amaya Puig-Kröger, Angel L. Corbí, Marcos J. Araúzo-Bravo, Ana M. Aransay, Carlos Lopez-Larrea
Published 2019-10-01