Trans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks

by Manuel Martínez-Bueno, Nina Oparina, Mikhail G. Dozmorov, Miranda C. Marion, Mary E. Comeau, Gary Gilkeson, Diane Kamen, Michael Weisman, Jane Salmon, Joseph W. McCune, John B. Harley, Robert Kimberly, Judith A. James, Joan Merrill, Courtney Montgomery, Carl D. Langefeld, Marta E. Alarcón-Riquelme
Published 2018-08-01

Intronic variants in the NFKB1 gene may influence hearing forecast in patients with unilateral sensorineural hearing loss in Meniere's disease.

by Sonia Cabrera, Elena Sanchez, Teresa Requena, Manuel Martinez-Bueno, Jesus Benitez, Nicolas Perez, Gabriel Trinidad, Andrés Soto-Varela, Sofía Santos-Perez, Eduardo Martin-Sanz, Jesus Fraile, Paz Perez, Marta E Alarcon-Riquelme, Angel Batuecas, Juan M Espinosa-Sanchez, Ismael Aran, Jose A Lopez-Escamez
Published 2014-01-01

A comprehensive database for integrated analysis of omics data in autoimmune diseases

by Jordi Martorell-Marugán, Raúl López-Domínguez, Adrián García-Moreno, Daniel Toro-Domínguez, Juan Antonio Villatoro-García, Guillermo Barturen, Adoración Martín-Gómez, Kevin Troule, Gonzalo Gómez-López, Fátima Al-Shahrour, Víctor González-Rumayor, María Peña-Chilet, Joaquín Dopazo, Julio Sáez-Rodríguez, Marta E. Alarcón-Riquelme, Pedro Carmona-Sáez
Published 2021-06-01

Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes.

by Kimberly E Taylor, Sharon A Chung, Robert R Graham, Ward A Ortmann, Annette T Lee, Carl D Langefeld, Chaim O Jacob, M Ilyas Kamboh, Marta E Alarcón-Riquelme, Betty P Tsao, Kathy L Moser, Patrick M Gaffney, John B Harley, Michelle Petri, Susan Manzi, Peter K Gregersen, Timothy W Behrens, Lindsey A Criswell
Published 2011-02-01

Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

by Sharon A Chung, Kimberly E Taylor, Robert R Graham, Joanne Nititham, Annette T Lee, Ward A Ortmann, Chaim O Jacob, Marta E Alarcón-Riquelme, Betty P Tsao, John B Harley, Patrick M Gaffney, Kathy L Moser, SLEGEN, Michelle Petri, F Yesim Demirci, M Ilyas Kamboh, Susan Manzi, Peter K Gregersen, Carl D Langefeld, Timothy W Behrens, Lindsey A Criswell
Published 2011-03-01

A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap.

by Paula S Ramos, Lindsey A Criswell, Kathy L Moser, Mary E Comeau, Adrienne H Williams, Nicholas M Pajewski, Sharon A Chung, Robert R Graham, Raphael Zidovetzki, Jennifer A Kelly, Kenneth M Kaufman, Chaim O Jacob, Timothy J Vyse, Betty P Tsao, Robert P Kimberly, Patrick M Gaffney, Marta E Alarcón-Riquelme, John B Harley, Carl D Langefeld, International Consortium on the Genetics of Systemic Erythematosus
Published 2011-12-01

Lupus risk variants in the PXK locus alter B-cell receptor internalization

by Samuel E. Vaughn, Samuel E. Vaughn, Corinne eFoley, Corinne eFoley, Xiaoming eLu, Zubin Hasmukh Patel, Zubin Hasmukh Patel, Erin E. Zoller, Albert F. Magnusen, Adrienne H. Williams, Julie T. Ziegler, Mary E. Comeau, Miranda C. Marion, Stuart B. Glenn, Adam eAdler, Nan eShen, Nan eShen, Swapan eNath, Anne M Stevens, Anne M Stevens, Barry I. Freedman, Betty P. Tsao, Chaim O. Jacob, Diane L Kamen, Elizabeth E Brown, Elizabeth E Brown, Gary S. Gilkeson, Graciela S. Alarcón, John D. Reveille, Juan-Manuel eAnaya, Judith A. James, Judith A. James, Kathy L. Moser, Lindsey A. Criswell, Luis M. Vilá, Marta E. Alarcon-Riquelme, Marta E. Alarcon-Riquelme, Michelle ePetri, R. Hal Scofield, R. Hal Scofield, R. Hal Scofield, Robert P. Kimberly, Rosalind eRamsey-Goldman, Young eBinjoo, Jeongim eChoi, Sang-Cheol eBae, Susan A. Boackle, Timothy J. Vyse, Joel M. Guthridge, Bahram eNamjou, Patrick M. Gaffney, Carl D. Langefeld, Kenneth M. Kaufman, Kenneth M. Kaufman, Jennifer A Kelly, Isaac TW Harley, John Barker Harley, John Barker Harley, Leah Claire Kottyan, Leah Claire Kottyan
Published 2015-01-01

A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome

by Perrine Soret, Christelle Le Dantec, Emiko Desvaux, Nathan Foulquier, Bastien Chassagnol, Sandra Hubert, Christophe Jamin, Guillermo Barturen, Guillaume Desachy, Valérie Devauchelle-Pensec, Cheïma Boudjeniba, Divi Cornec, Alain Saraux, Sandrine Jousse-Joulin, Nuria Barbarroja, Ignasi Rodríguez-Pintó, Ellen De Langhe, Lorenzo Beretta, Carlo Chizzolini, László Kovács, Torsten Witte, PRECISESADS Clinical Consortium, PRECISESADS Flow Cytometry Consortium, Eléonore Bettacchioli, Anne Buttgereit, Zuzanna Makowska, Ralf Lesche, Maria Orietta Borghi, Javier Martin, Sophie Courtade-Gaiani, Laura Xuereb, Mickaël Guedj, Philippe Moingeon, Marta E. Alarcón-Riquelme, Laurence Laigle, Jacques-Olivier Pers
Published 2021-06-01

The Role of Genetic Variation Near Interferon-Kappa in Systemic Lupus Erythematosus

by Isaac T. W. Harley, Timothy B. Niewold, Rebecca M. Stormont, Kenneth M. Kaufman, Stuart B. Glenn, Beverly S. Franek, Jennifer A. Kelly, Jeffrey R. Kilpatrick, David Hutchings, Jasmin Divers, Gail R. Bruner, Jeffrey C. Edberg, Gerald McGwin, Michelle A. Petri, Rosalind Ramsey-Goldman, John D. Reveille, Luis M. Vilá-Pérez, Joan T. Merrill, Gary S. Gilkeson, Timothy J. Vyse, Marta E. Alarcón-Riquelme, Soo-Kyung Cho, Chaim O. Jacob, Graciela S. Alarcón, Kathy L. Moser, Patrick M. Gaffney, Robert P. Kimberly, Sang-Cheol Bae, Carl D. Langefeld, John B. Harley, Joel M. Guthridge, Judith A. James
Published 2010-01-01

Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production.

by Julio E Molineros, Amit K Maiti, Celi Sun, Loren L Looger, Shizhong Han, Xana Kim-Howard, Stuart Glenn, Adam Adler, Jennifer A Kelly, Timothy B Niewold, Gary S Gilkeson, Elizabeth E Brown, Graciela S Alarcón, Jeffrey C Edberg, Michelle Petri, Rosalind Ramsey-Goldman, John D Reveille, Luis M Vilá, Barry I Freedman, Betty P Tsao, Lindsey A Criswell, Chaim O Jacob, Jason H Moore, Timothy J Vyse, Carl L Langefeld, Joel M Guthridge, Patrick M Gaffney, Kathy L Moser, R Hal Scofield, Marta E Alarcón-Riquelme, BIOLUPUS Network, Scott M Williams, Joan T Merrill, Judith A James, Kenneth M Kaufman, Robert P Kimberly, John B Harley, Swapan K Nath
Published 2013-01-01

PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes.

by Bahram Namjou, Xana Kim-Howard, Celi Sun, Adam Adler, Sharon A Chung, Kenneth M Kaufman, Jennifer A Kelly, Stuart B Glenn, Joel M Guthridge, Robert H Scofield, Robert P Kimberly, Elizabeth E Brown, Graciela S Alarcón, Jeffrey C Edberg, Jae-Hoon Kim, Jiyoung Choi, Rosalind Ramsey-Goldman, Michelle A Petri, John D Reveille, Luis M Vilá, Susan A Boackle, Barry I Freedman, Betty P Tsao, Carl D Langefeld, Timothy J Vyse, Chaim O Jacob, Bernardo Pons-Estel, Argentine Collaborative Group, Timothy B Niewold, Kathy L Moser Sivils, Joan T Merrill, Juan-Manuel Anaya, Gary S Gilkeson, Patrick M Gaffney, Sang-Cheol Bae, Marta E Alarcón-Riquelme, BIOLUPUS and GENLES Networks, John B Harley, Lindsey A Criswell, Judith A James, Swapan K Nath
Published 2013-01-01

Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.

by Jian Zhao, Hui Wu, Melanie Khosravi, Huijuan Cui, Xiaoxia Qian, Jennifer A Kelly, Kenneth M Kaufman, Carl D Langefeld, Adrienne H Williams, Mary E Comeau, Julie T Ziegler, Miranda C Marion, Adam Adler, Stuart B Glenn, Marta E Alarcón-Riquelme, BIOLUPUS Network, GENLES Network, Bernardo A Pons-Estel, John B Harley, Sang-Cheol Bae, So-Young Bang, Soo-Kyung Cho, Chaim O Jacob, Timothy J Vyse, Timothy B Niewold, Patrick M Gaffney, Kathy L Moser, Robert P Kimberly, Jeffrey C Edberg, Elizabeth E Brown, Graciela S Alarcon, Michelle A Petri, Rosalind Ramsey-Goldman, Luis M Vilá, John D Reveille, Judith A James, Gary S Gilkeson, Diane L Kamen, Barry I Freedman, Juan-Manuel Anaya, Joan T Merrill, Lindsey A Criswell, R Hal Scofield, Anne M Stevens, Joel M Guthridge, Deh-Ming Chang, Yeong Wook Song, Ji Ah Park, Eun Young Lee, Susan A Boackle, Jennifer M Grossman, Bevra H Hahn, Timothy H J Goodship, Rita M Cantor, Chack-Yung Yu, Nan Shen, Betty P Tsao
Published 2011-05-01

Molecular Characterization of Monocyte Subsets Reveals Specific and Distinctive Molecular Signatures Associated With Cardiovascular Disease in Rheumatoid Arthritis

by Patricia Ruiz-Limon, Rafaela Ortega-Castro, Nuria Barbarroja, Nuria Barbarroja, Carlos Perez-Sanchez, Christophe Jamin, Alejandra Maria Patiño-Trives, Maria Luque-Tevar, Alejandro Ibáñez-Costa, Laura Perez-Sanchez, Iván Arias de la Rosa, MaCarmen Abalos-Aguilera, Yolanda Jimenez-Gomez, Jerusalem Calvo-Gutierrez, Pilar Font, Alejandro Escudero-Contreras, Marta E. Alarcon-Riquelme, Eduardo Collantes-Estevez, Chary López-Pedrera, the PRECISESADS Clinical Consortium and Flow Cytometry Study Group, C Marañón, L Le Lann, N Varela, B Muchmore, A Dufour, Alvarez, C Carlo Montserrat Chizzolini, E, NB De Langhe, CL-P, V Gerl, A De Groof, J Ducreux, E Trombetta, T Li, D Alvarez-Errico, S Rao, JO Pers, L Beretta, R AguilarQuesada, MA Aguirre-Zamorano, JL Callejas Rubio, MC Castro-Villegas, R Cervera, C Chizzolini, E Collantes, D Cornec, E De Langhe, V Devauchelle-Pensec, AE-C, G Espinosa, MC Fernández Roldán, T Gomes Anjos, F Hiepe, I Jiménez Moleón, S Jousse-Joulin, B Lauwerys, A López-Berrio, R Lories, J Marovac, PL Meroni, B Miranda, H Navarro-Linares, R Ortega-Castro, N Ortego, JO Pers, E Ramón Garrido, E Raya, R Ríos Fernández, I Rodríguez-Pintó, A Saraux
Published 2019-05-01

Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children

by Noam D. Beckmann, Phillip H. Comella, Esther Cheng, Lauren Lepow, Aviva G. Beckmann, Scott R. Tyler, Konstantinos Mouskas, Nicole W. Simons, Gabriel E. Hoffman, Nancy J. Francoeur, Diane Marie Del Valle, Gurpawan Kang, Anh Do, Emily Moya, Lillian Wilkins, Jessica Le Berichel, Christie Chang, Robert Marvin, Sharlene Calorossi, Alona Lansky, Laura Walker, Nancy Yi, Alex Yu, Jonathan Chung, Matthew Hartnett, Melody Eaton, Sandra Hatem, Hajra Jamal, Alara Akyatan, Alexandra Tabachnikova, Lora E. Liharska, Liam Cotter, Brian Fennessy, Akhil Vaid, Guillermo Barturen, Hardik Shah, Ying-chih Wang, Shwetha Hara Sridhar, Juan Soto, Swaroop Bose, Kent Madrid, Ethan Ellis, Elyze Merzier, Konstantinos Vlachos, Nataly Fishman, Manying Tin, Melissa Smith, Hui Xie, Manishkumar Patel, Kai Nie, Kimberly Argueta, Jocelyn Harris, Neha Karekar, Craig Batchelor, Jose Lacunza, Mahlet Yishak, Kevin Tuballes, Ieisha Scott, Arvind Kumar, Suraj Jaladanki, Charuta Agashe, Ryan Thompson, Evan Clark, Bojan Losic, Lauren Peters, The Mount Sinai COVID-19 Biobank Team, Panagiotis Roussos, Jun Zhu, Wenhui Wang, Andrew Kasarskis, Benjamin S. Glicksberg, Girish Nadkarni, Dusan Bogunovic, Cordelia Elaiho, Sandeep Gangadharan, George Ofori-Amanfo, Kasey Alesso-Carra, Kenan Onel, Karen M. Wilson, Carmen Argmann, Supinda Bunyavanich, Marta E. Alarcón-Riquelme, Thomas U. Marron, Adeeb Rahman, Seunghee Kim-Schulze, Sacha Gnjatic, Bruce D. Gelb, Miriam Merad, Robert Sebra, Eric E. Schadt, Alexander W. Charney
Published 2021-08-01

Transancestral mapping and genetic load in systemic lupus erythematosus

by Carl D. Langefeld, Hannah C. Ainsworth, Deborah S. Cunninghame Graham, Jennifer A. Kelly, Mary E. Comeau, Miranda C. Marion, Timothy D. Howard, Paula S. Ramos, Jennifer A. Croker, David L. Morris, Johanna K. Sandling, Jonas Carlsson Almlöf, Eduardo M. Acevedo-Vásquez, Graciela S. Alarcón, Alejandra M. Babini, Vicente Baca, Anders A. Bengtsson, Guillermo A. Berbotto, Marc Bijl, Elizabeth E. Brown, Hermine I. Brunner, Mario H. Cardiel, Luis Catoggio, Ricard Cervera, Jorge M. Cucho-Venegas, Solbritt Rantapää Dahlqvist, Sandra D’Alfonso, Berta Martins Da Silva, Iñigo de la Rúa Figueroa, Andrea Doria, Jeffrey C. Edberg, Emőke Endreffy, Jorge A. Esquivel-Valerio, Paul R. Fortin, Barry I. Freedman, Johan Frostegård, Mercedes A. García, Ignacio García de la Torre, Gary S. Gilkeson, Dafna D. Gladman, Iva Gunnarsson, Joel M. Guthridge, Jennifer L. Huggins, Judith A. James, Cees G. M. Kallenberg, Diane L. Kamen, David R. Karp, Kenneth M. Kaufman, Leah C. Kottyan, László Kovács, Helle Laustrup, Bernard R. Lauwerys, Quan-Zhen Li, Marco A. Maradiaga-Ceceña, Javier Martín, Joseph M. McCune, David R. McWilliams, Joan T. Merrill, Pedro Miranda, José F. Moctezuma, Swapan K. Nath, Timothy B. Niewold, Lorena Orozco, Norberto Ortego-Centeno, Michelle Petri, Christian A. Pineau, Bernardo A. Pons-Estel, Janet Pope, Prithvi Raj, Rosalind Ramsey-Goldman, John D. Reveille, Laurie P. Russell, José M. Sabio, Carlos A. Aguilar-Salinas, Hugo R. Scherbarth, Raffaella Scorza, Michael F. Seldin, Christopher Sjöwall, Elisabet Svenungsson, Susan D. Thompson, Sergio M. A. Toloza, Lennart Truedsson, Teresa Tusié-Luna, Carlos Vasconcelos, Luis M. Vilá, Daniel J. Wallace, Michael H. Weisman, Joan E. Wither, Tushar Bhangale, Jorge R. Oksenberg, John D. Rioux, Peter K. Gregersen, Ann-Christine Syvänen, Lars Rönnblom, Lindsey A. Criswell, Chaim O. Jacob, Kathy L. Sivils, Betty P. Tsao, Laura E. Schanberg, Timothy W. Behrens, Earl D. Silverman, Marta E. Alarcón-Riquelme, Robert P. Kimberly, John B. Harley, Edward K. Wakeland, Robert R. Graham, Patrick M. Gaffney, Timothy J. Vyse
Published 2017-07-01