ArchiLD: hierarchical visualization of linkage disequilibrium in human populations.

by Rossella Melchiotti, Olaf Rötzschke, Michael Poidinger
Published 2014-01-01

Absence of leucine zipper in the natural FOXP3Delta2Delta7 isoform does not affect dimerization but abrogates suppressive capacity.

by Reiner K W Mailer, Kirsten Falk, Olaf Rötzschke
Published 2009-07-01

Active suppression induced by repetitive self-epitopes protects against EAE development.

by Fabiola Puentes, Katharina Dickhaut, Maria Hofstätter, Kirsten Falk, Olaf Rötzschke
Published 2013-01-01

New Insights into Immune-Mediated Mechanisms in Parkinson’s Disease

by Jolene Su Yi Tan, Yin Xia Chao, Olaf Rötzschke, Eng-King Tan
Published 2020-12-01

Are We Ready for the Use of Foxp3+ Regulatory T Cells for Immunodiagnosis and Immunotherapy in Kidney Transplantation?

by Francisco Salcido-Ochoa, Nurhashikin Yusof, Susan Swee-Shan Hue, Doreen Haase, Terence Kee, Olaf Rotzschke
Published 2012-01-01

Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules.

by Shashank Gupta, Sabine Höpner, Bernd Rupp, Sebastian Günther, Katharina Dickhaut, Noopur Agarwal, M Cristina Cardoso, Ronald Kühne, Karl-Heinz Wiesmüller, Günther Jung, Kirsten Falk, Olaf Rötzschke
Published 2008-01-01

Characterization of structural features controlling the receptiveness of empty class II MHC molecules.

by Bernd Rupp, Sebastian Günther, Talat Makhmoor, Andreas Schlundt, Katharina Dickhaut, Shashank Gupta, Iqbal Choudhary, Karl-Heinz Wiesmüller, Günther Jung, Christian Freund, Kirsten Falk, Olaf Rötzschke, Ronald Kühne
Published 2011-01-01

Gut–Brain Axis: Potential Factors Involved in the Pathogenesis of Parkinson's Disease

by Yin-Xia Chao, Yin-Xia Chao, Yin-Xia Chao, Muhammad Yaaseen Gulam, Nicholas Shyh Jenn Chia, Lei Feng, Olaf Rotzschke, Eng-King Tan, Eng-King Tan, Eng-King Tan
Published 2020-08-01

Corrigendum: Gut–Brain Axis: Potential Factors Involved in the Pathogenesis of Parkinson's Disease

by Yin-Xia Chao, Yin-Xia Chao, Yin-Xia Chao, Muhammad Yaaseen Gulam, Nicholas Shyh Jenn Chia, Lei Feng, Olaf Rotzschke, Eng-King Tan, Eng-King Tan, Eng-King Tan
Published 2020-11-01

Analysis of T Cell Subsets in Adult Primary/Idiopathic Minimal Change Disease: A Pilot Study

by Francisco Salcido-Ochoa, Susan Swee-Shan Hue, Doreen Haase, Jason Chon Jun Choo, Nurhashikin Yusof, Reiko Lixiang Li, John Carson Allen, Jabed Iqbal, Alwin Hwai Liang Loh, Olaf Rotzschke
Published 2017-01-01

A Co-culture Model of PBMC and Stem Cell Derived Human Nasal Epithelium Reveals Rapid Activation of NK and Innate T Cells Upon Influenza A Virus Infection of the Nasal Epithelium

by Annika Luukkainen, Annika Luukkainen, Kia Joo Puan, Nurhashikin Yusof, Bernett Lee, Kai Sen Tan, Jing Liu, Yan Yan, Sanna Toppila-Salmi, Sanna Toppila-Salmi, Risto Renkonen, Risto Renkonen, Vincent T. Chow, Olaf Rotzschke, De Yun Wang
Published 2018-11-01

RNA Sequencing of H3N2 Influenza Virus-Infected Human Nasal Epithelial Cells from Multiple Subjects Reveals Molecular Pathways Associated with Tissue Injury and Complications

by Kai Sen Tan, Anand Kumar Andiappan, Bernett Lee, Yan Yan, Jing Liu, See Aik Tang, Josephine Lum, Ting Ting He, Yew Kwang Ong, Mark Thong, Hui Fang Lim, Hyung Won Choi, Olaf Rotzschke, Vincent T Chow, De Yun Wang
Published 2019-08-01

Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease

by Ma’en Obeidat, Yunlong Nie, Virginia Chen, Casey P. Shannon, Anand Kumar Andiappan, Bernett Lee, Olaf Rotzschke, Peter J. Castaldi, Craig P. Hersh, Nick Fishbane, Raymond T. Ng, Bruce McManus, Bruce E. Miller, Stephen Rennard, Peter D. Paré, Don D. Sin
Published 2017-04-01

FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression

by Kia Joo Puan, Boris San Luis, Nurhashikin Yusof, Dilip Kumar, Anand Kumar Andiappan, Wendy Lee, Samanta Cajic, Dragana Vuckovic, Jing De Chan, Tobias Döllner, Han Wei Hou, Yunxuan Jiang, Chao Tian, the 23andMe Research Team, Erdmann Rapp, Michael Poidinger, De Yun Wang, Nicole Soranzo, Bernett Lee, Olaf Rötzschke
Published 2021-07-01

Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19

by Guillaume Carissimo, Weili Xu, Immanuel Kwok, Mohammad Yazid Abdad, Yi-Hao Chan, Siew-Wai Fong, Kia Joo Puan, Cheryl Yi-Pin Lee, Nicholas Kim-Wah Yeo, Siti Naqiah Amrun, Rhonda Sin-Ling Chee, Wilson How, Stephrene Chan, Bingwen Eugene Fan, Anand Kumar Andiappan, Bernett Lee, Olaf Rötzschke, Barnaby Edward Young, Yee-Sin Leo, David Chien Lye, Laurent Renia, Lai Guan Ng, Anis Larbi, Lisa FP Ng
Published 2020-10-01

Targeting Glycolysis in Macrophages Confers Protection Against Pancreatic Ductal Adenocarcinoma

by Hweixian Leong Penny, Je Lin Sieow, Sin Yee Gun, Mai Chan Lau, Bernett Lee, Jasmine Tan, Cindy Phua, Florida Toh, Yvonne Nga, Wei Hseun Yeap, Baptiste Janela, Dilip Kumar, Hao Chen, Joe Yeong, Justin A. Kenkel, Angela Pang, Diana Lim, Han Chong Toh, Tony Lim Kiat Hon, Christopher I. Johnson, Hanif Javanmard Khameneh, Alessandra Mortellaro, Edgar G. Engleman, Olaf Rotzschke, Florent Ginhoux, Jean-Pierre Abastado, Jinmiao Chen, Siew Cheng Wong
Published 2021-06-01

Asymptomatic COVID‐19: disease tolerance with efficient anti‐viral immunity against SARS‐CoV‐2

by Yi‐Hao Chan, Siew‐Wai Fong, Chek‐Meng Poh, Guillaume Carissimo, Nicholas Kim‐Wah Yeo, Siti Naqiah Amrun, Yun Shan Goh, Jackwee Lim, Weili Xu, Rhonda Sin‐Ling Chee, Anthony Torres‐Ruesta, Cheryl Yi‐Pin Lee, Matthew Zirui Tay, Zi Wei Chang, Wen‐Hsin Lee, Bei Wang, Seow‐Yen Tan, Shirin Kalimuddin, Barnaby Edward Young, Yee‐Sin Leo, Cheng‐I Wang, Bernett Lee, Olaf Rötzschke, David Chien Lye, Laurent Renia, Lisa F P Ng
Published 2021-06-01

T-Cell Lymphoma Clonality by Copy Number Variation Analysis of T-Cell Receptor Genes

by Ming Liang Oon, Jing Quan Lim, Bernett Lee, Sai Mun Leong, Gwyneth Shook-Ting Soon, Zi Wei Wong, Evelyn Huizi Lim, Zhenhua Li, Allen Eng Juh Yeoh, Shangying Chen, Kenneth Hon Kim Ban, Tae-Hoon Chung, Soo-Yong Tan, Shih-Sung Chuang, Seiichi Kato, Shigeo Nakamura, Emiko Takahashi, Yong-Howe Ho, Joseph D Khoury, Rex K. H. Au-Yeung, Chee-Leong Cheng, Soon-Thye Lim, Wee-Joo Chng, Claudio Tripodo, Olaf Rotzschke, Choon Kiat Ong, Siok-Bian Ng
Published 2021-01-01

A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus

by Dilip Kumar, Kia Joo Puan, Anand Kumar Andiappan, Bernett Lee, Geertje H. A. Westerlaken, Doreen Haase, Rossella Melchiotti, Zhuang Li, Nurhashikin Yusof, Josephine Lum, Geraldine Koh, Shihui Foo, Joe Yeong, Alexessander Couto Alves, Juha Pekkanen, Liang Dan Sun, Astrid Irwanto, Benjamin P. Fairfax, Vivek Naranbhai, John E. A. Common, Mark Tang, Chin Keh Chuang, Marjo-Riitta Jarvelin, Julian C. Knight, Xuejun Zhang, Fook Tim Chew, Shyam Prabhakar, Liu Jianjun, De Yun Wang, Francesca Zolezzi, Michael Poidinger, E. Birgitte Lane, Linde Meyaard, Olaf Rötzschke
Published 2017-02-01

Cell Specific eQTL Analysis without Sorting Cells.

by Harm-Jan Westra, Danny Arends, Tõnu Esko, Marjolein J Peters, Claudia Schurmann, Katharina Schramm, Johannes Kettunen, Hanieh Yaghootkar, Benjamin P Fairfax, Anand Kumar Andiappan, Yang Li, Jingyuan Fu, Juha Karjalainen, Mathieu Platteel, Marijn Visschedijk, Rinse K Weersma, Silva Kasela, Lili Milani, Liina Tserel, Pärt Peterson, Eva Reinmaa, Albert Hofman, André G Uitterlinden, Fernando Rivadeneira, Georg Homuth, Astrid Petersmann, Roberto Lorbeer, Holger Prokisch, Thomas Meitinger, Christian Herder, Michael Roden, Harald Grallert, Samuli Ripatti, Markus Perola, Andrew R Wood, David Melzer, Luigi Ferrucci, Andrew B Singleton, Dena G Hernandez, Julian C Knight, Rossella Melchiotti, Bernett Lee, Michael Poidinger, Francesca Zolezzi, Anis Larbi, De Yun Wang, Leonard H van den Berg, Jan H Veldink, Olaf Rotzschke, Seiko Makino, Veikko Salomaa, Konstantin Strauch, Uwe Völker, Joyce B J van Meurs, Andres Metspalu, Cisca Wijmenga, Ritsert C Jansen, Lude Franke
Published 2015-05-01