The piggyBac transposon-mediated expression of SV40 T antigen efficiently immortalizes mouse embryonic fibroblasts (MEFs).

by Ning Wang, Wenwen Zhang, Jing Cui, Hongmei Zhang, Xiang Chen, Ruidong Li, Ningning Wu, Xian Chen, Sheng Wen, Junhui Zhang, Liangjun Yin, Fang Deng, Zhan Liao, Zhonglin Zhang, Qian Zhang, Zhengjian Yan, Wei Liu, Jixing Ye, Youlin Deng, Zhongliang Wang, Min Qiao, Hue H Luu, Rex C Haydon, Lewis L Shi, Houjie Liang, Tong-Chuan He
Published 2014-01-01

Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture

by Qian Zhang, Julia Sidorenko, Baptiste Couvy-Duchesne, Riccardo E. Marioni, Margaret J. Wright, Alison M. Goate, Edoardo Marcora, Kuan-lin Huang, Tenielle Porter, Simon M. Laws, Australian Imaging Biomarkers and Lifestyle (AIBL) Study, Perminder S. Sachdev, Karen A. Mather, Nicola J. Armstrong, Anbupalam Thalamuthu, Henry Brodaty, Loic Yengo, Jian Yang, Naomi R. Wray, Allan F. McRae, Peter M. Visscher
Published 2020-09-01

Genetic risk of clozapine-induced leukopenia and neutropenia: a genome-wide association study

by Jianhua Chen, Ping Yang, Qian Zhang, Ruirui Chen, Peng Wang, Benxiu Liu, Wensheng Sun, Xuemin Jian, Siying Xiang, Juan Zhou, Ningning Li, Ke Wang, Chengwen Gao, Yanqin Wen, Chuanhong Wu, Jinmai Zhang, Yalin Zhao, Qiangzhen Yang, Meihang Li, Robert Stewart, Yuanchao Sun, Dun Pan, Yujuan Niu, Zhuo Wang, Yifeng Xu, Xingwang Li, Lin He, Zhiqiang Li, Yongyong Shi
Published 2021-06-01

An epigenome-wide association study of sex-specific chronological ageing

by Daniel L. McCartney, Futao Zhang, Robert F. Hillary, Qian Zhang, Anna J. Stevenson, Rosie M. Walker, Mairead L. Bermingham, Thibaud Boutin, Stewart W. Morris, Archie Campbell, Alison D. Murray, Heather C. Whalley, David J. Porteous, Caroline Hayward, Kathryn L. Evans, Tamir Chandra, Ian J. Deary, Andrew M. McIntosh, Jian Yang, Peter M. Visscher, Allan F. McRae, Riccardo E. Marioni
Published 2019-12-01

Epigenetic prediction of complex traits and death

by Daniel L. McCartney, Robert F. Hillary, Anna J. Stevenson, Stuart J. Ritchie, Rosie M. Walker, Qian Zhang, Stewart W. Morris, Mairead L. Bermingham, Archie Campbell, Alison D. Murray, Heather C. Whalley, Catharine R. Gale, David J. Porteous, Chris S. Haley, Allan F. McRae, Naomi R. Wray, Peter M. Visscher, Andrew M. McIntosh, Kathryn L. Evans, Ian J. Deary, Riccardo E. Marioni
Published 2018-09-01

Author Correction: Bayesian reassessment of the epigenetic architecture of complex traits

by Daniel Trejo Banos, Daniel L. McCartney, Marion Patxot, Lucas Anchieri, Thomas Battram, Colette Christiansen, Ricardo Costeira, Rosie M. Walker, Stewart W. Morris, Archie Campbell, Qian Zhang, David J. Porteous, Allan F. McRae, Naomi R. Wray, Peter M. Visscher, Chris S. Haley, Kathryn L. Evans, Ian J. Deary, Andrew M. McIntosh, Gibran Hemani, Jordana T. Bell, Riccardo E. Marioni, Matthew R. Robinson
Published 2020-10-01

Bayesian reassessment of the epigenetic architecture of complex traits

by Daniel Trejo Banos, Daniel L. McCartney, Marion Patxot, Lucas Anchieri, Thomas Battram, Colette Christiansen, Ricardo Costeira, Rosie M. Walker, Stewart W. Morris, Archie Campbell, Qian Zhang, David J. Porteous, Allan F. McRae, Naomi R. Wray, Peter M. Visscher, Chris S. Haley, Kathryn L. Evans, Ian J. Deary, Andrew M. McIntosh, Gibran Hemani, Jordana T. Bell, Riccardo E. Marioni, Matthew R. Robinson
Published 2020-06-01

Efficacy, immunogenicity and safety of the AS04‐HPV‐16/18 vaccine in Chinese women aged 18‐25 years: End‐of‐study results from a phase II/III, randomised, controlled trial...

by Feng‐Cai Zhu, Shang‐Ying Hu, Ying Hong, Yue‐Mei Hu, Xun Zhang, Yi‐Ju Zhang, Qin‐Jing Pan, Wen‐Hua Zhang, Fang‐Hui Zhao, Cheng‐Fu Zhang, Xiaoping Yang, Jia‐Xi Yu, Jiahong Zhu, Yejiang Zhu, Feng Chen, Qian Zhang, Hong Wang, Changrong Wang, Jun Bi, Shiyin Xue, Lingling Shen, Yan‐Shu Zhang, Yunkun He, Haiwen Tang, Naveen Karkada, Pemmaraju Suryakiran, Dan Bi, Frank Struyf
Published 2019-10-01

A CRISPR-Cas12a-derived biosensing platform for the highly sensitive detection of diverse small molecules

by Mindong Liang, Zilong Li, Weishan Wang, Jiakun Liu, Leshi Liu, Guoliang Zhu, Loganathan Karthik, Man Wang, Ke-Feng Wang, Zhong Wang, Jing Yu, Yuting Shuai, Jiaming Yu, Lu Zhang, Zhiheng Yang, Chuan Li, Qian Zhang, Tong Shi, Liming Zhou, Feng Xie, Huanqin Dai, Xueting Liu, Jingyu Zhang, Guang Liu, Ying Zhuo, Buchang Zhang, Chenli Liu, Shanshan Li, Xuekui Xia, Yaojun Tong, Yanwen Liu, Gil Alterovitz, Gao-Yi Tan, Li-Xin Zhang
Published 2019-08-01

Reversibly Immortalized Mouse Articular Chondrocytes Acquire Long-Term Proliferative Capability While Retaining Chondrogenic Phenotype

by Joseph D. Lamplot, Bo Liu, Liangjun Yin, Wenwen Zhang, Zhongliang Wang, Gaurav Luther, Eric Wagner, Ruidong Li, Guoxin Nan, Wei Shui, Zhengjian Yan, Richard Rames, Fang Deng, Hongmei Zhang, Zhan Liao, Wei Liu, Junhui Zhang, Zhonglin Zhang, Qian Zhang, Jixing Ye, Youlin Deng, Min Qiao, Rex C. Haydon, Hue H. Luu, Jovito Angeles, Lewis L. Shi, Tong-Chuan He M.D., Ph.D., Sherwin H. Ho M.D.
Published 2015-06-01

Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease

by Costanza L. Vallerga, Futao Zhang, Javed Fowdar, Allan F. McRae, Ting Qi, Marta F. Nabais, Qian Zhang, Irfahan Kassam, Anjali K. Henders, Leanne Wallace, Grant Montgomery, Yu-Hsuan Chuang, Steve Horvath, Beate Ritz, Glenda Halliday, Ian Hickie, John B. Kwok, John Pearson, Toni Pitcher, Martin Kennedy, Steven R. Bentley, Peter A. Silburn, Jian Yang, Naomi R. Wray, Simon J. G. Lewis, Tim Anderson, John Dalrymple-Alford, George D. Mellick, Peter M. Visscher, Jacob Gratten
Published 2020-03-01

Protocol on transcranial alternating current stimulation for the treatment of major depressive disorder: a randomized controlled trial

by Hong-Xing Wang, Kun Wang, Wen-Rui Zhang, Wen-Feng Zhao, Xiao-Tong Yang, Li Wang, Mao Peng, Zhi-Chao Sun, Qing Xue, Yu Jia, Ning Li, Kai Dong, Qian Zhang, Shu-Qin Zhan, Bao-Quan Min, Chun-Qiu Fan, Ai-Hong Zhou, Hai-Qing Song, Lu Yin, Tian-Mei Si, Jing Huang, Jie Lu, Hai-Xia Leng, Wei-Jun Ding, Yuan Liu, Tian-Yi Yan, Yu-Ping Wang, Li-Min Chen
Published 2020-01-01

Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension

by Haiyang Tang, PhD, Kang Wu, MD, PhD, Jian Wang, MD, Sujana Vinjamuri, MD, MS, Yali Gu, MS, RN, Shanshan Song, MD, PhD, Ziyi Wang, MD, Qian Zhang, MD, Angela Balistrieri, Ramon J. Ayon, PhD, Franz Rischard, MD, Rebecca Vanderpool, PhD, Jiwang Chen, PhD, Guofei Zhou, PhD, Ankit A. Desai, MD, Stephen M. Black, PhD, Joe G.N. Garcia, MD, Jason X.-J. Yuan, MD, PhD, Ayako Makino, PhD
Published 2018-12-01

Adeno-Associated Virus Serotype 9–Driven Expression of BAG3 Improves Left Ventricular Function in Murine Hearts With Left Ventricular Dysfunction Secondary to a Myocardial Infarcti...

by Tijana Knezevic, PhD, Valerie D. Myers, MS, Feifei Su, MD, PhD, JuFang Wang, MD, Jianliang Song, MD, PhD, Xue-Qian Zhang, MD, Erhe Gao, MD, PhD, Guofeng Gao, MD, PhD, Muniswamy Madesh, PhD, Manish K. Gupta, PhD, Jennifer Gordon, PhD, Kristen N. Weiner, BS, Joseph Rabinowitz, PhD, Frederick V. Ramsey, PhD, Douglas G. Tilley, PhD, Kamel Khalili, PhD, Joseph Y. Cheung, MD, PhD, Arthur M. Feldman, MD, PhD
Published 2016-12-01

Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

by Qian Zhang, Costanza L. Vallerga, Rosie M. Walker, Tian Lin, Anjali K. Henders, Grant W. Montgomery, Ji He, Dongsheng Fan, Javed Fowdar, Martin Kennedy, Toni Pitcher, John Pearson, Glenda Halliday, John B. Kwok, Ian Hickie, Simon Lewis, Tim Anderson, Peter A. Silburn, George D. Mellick, Sarah E. Harris, Paul Redmond, Alison D. Murray, David J. Porteous, Christopher S. Haley, Kathryn L. Evans, Andrew M. McIntosh, Jian Yang, Jacob Gratten, Riccardo E. Marioni, Naomi R. Wray, Ian J. Deary, Allan F. McRae, Peter M. Visscher
Published 2019-08-01

Chinese Stroke Association guidelines for clinical management of cerebrovascular disorders: executive summary and 2019 update of clinical management of intracerebral haemorrhage

by Liping Liu, Anding Xu, Xin Wang, Yongjun Wang, Kangning Chen, Yilong Wang, Zhongrong Miao, Yuming Xu, Benyan Luo, Bin Peng, Li Guo, Yong Huo, Li He, Qiang Dong, Xingquan Zhao, Jizong Zhao, Wei Wang, Shuo Wang, Chen Wang, Meng Zhao, Linong Ji, Shizheng Wu, Wen Wang, Yi Yang, Junbo Ge, Xunming Ji, Tao Yu, Qian Zhang, Tong Zhang, Bo Hu, Tielin Li, Ning Wang, Peng Xie, Yun Xu, Jinsheng Zeng, Chaodong Zhang, Zhuo Zhang, Gang Zhao, Ji Zong Zhao, Xiaoyuan Niu, Dingfeng Su, Beisha Tang, Yong Cao, Songlin Yu, Yanfang Liu, Zhenghui Sun

A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes

by Yu Guo, Lisu Huang, Guangshun Zhang, Yanfeng Yao, He Zhou, Shu Shen, Bingqing Shen, Bo Li, Xin Li, Qian Zhang, Mingjie Chen, Da Chen, Jia Wu, Dan Fu, Xinxin Zeng, Mingfang Feng, Chunjiang Pi, Yuan Wang, Xingdong Zhou, Minmin Lu, Yarong Li, Yaohui Fang, Yun-Yueh Lu, Xue Hu, Shanshan Wang, Wanju Zhang, Ge Gao, Francisco Adrian, Qisheng Wang, Feng Yu, Yun Peng, Alexander G. Gabibov, Juan Min, Yuhui Wang, Heyu Huang, Alexey Stepanov, Wei Zhang, Yan Cai, Junwei Liu, Zhiming Yuan, Chen Zhang, Zhiyong Lou, Fei Deng, Hongkai Zhang, Chao Shan, Liang Schweizer, Kun Sun, Zihe Rao
Published 2021-05-01

Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients

by Jing Liu, Sumeng Li, Jia Liu, Boyun Liang, Xiaobei Wang, Hua Wang, Wei Li, Qiaoxia Tong, Jianhua Yi, Lei Zhao, Lijuan Xiong, Chunxia Guo, Jin Tian, Jinzhuo Luo, Jinghong Yao, Ran Pang, Hui Shen, Cheng Peng, Ting Liu, Qian Zhang, Jun Wu, Ling Xu, Sihong Lu, Baoju Wang, Zhihong Weng, Chunrong Han, Huabing Zhu, Ruxia Zhou, Helong Zhou, Xiliu Chen, Pian Ye, Bin Zhu, Lu Wang, Wenqing Zhou, Shengsong He, Yongwen He, Shenghua Jie, Ping Wei, Jianao Zhang, Yinping Lu, Weixian Wang, Li Zhang, Ling Li, Fengqin Zhou, Jun Wang, Ulf Dittmer, Mengji Lu, Yu Hu, Dongliang Yang, Xin Zheng
Published 2020-05-01

A Cross-Sectional Nationwide Study on Accessibility and Availability of Neonatal care Resources in Hospitals of China: Current Situation, Mortality and Regional Differences

by Qiuping Li, MD, Xing Li, MD, Qian Zhang, MD, Yanping Zhang, MD, Ling Liu, MD, Xiuyong Cheng, MD, Bin Yi, MD, Jian Mao, MD, Chao Chen, MD, Shaoru He, MD, Li Liu, MD, Xiaoyu Zhou, MD, Xianmei Lu, MD, Zhenlang Lin, MD, Jun Zheng, MD, Xiao Chen, MD, Shiwen Xia, MD, Yangfang Li, MD, Shaojie Yue, MD, Chaoying Yan, MD, Xinzhu Lin, MD, Zhuying Wang, MD, Jun Tang, MD, Yang Wang, MD, Danni Zhong, MD, Li Ma, MD, Yanxiang Chen, MD, Mingxia Li, MD, Hua Mei, MD, Kezhan Liu, MD, Ling Yang, MD, Xiaorong Wang, MD, Hong Wu, MD, Yuan Shi, MD, Zhichun Feng, MD
Published 2021-09-01