Beyond association: successes and challenges in linking non-coding genetic variation to functional consequences that modulate Alzheimer’s disease risk

by Gloriia Novikova, Shea J. Andrews, Alan E. Renton, Edoardo Marcora
Published 2021-04-01

The variant call format provides efficient and robust storage of GWAS summary statistics

by Matthew S. Lyon, Shea J. Andrews, Ben Elsworth, Tom R. Gaunt, Gibran Hemani, Edoardo Marcora
Published 2021-01-01

Alzheimer's-associated PU.1 expression levels regulate microglial inflammatory response

by Anna A. Pimenova, Manon Herbinet, Ishaan Gupta, Saima I. Machlovi, Kathryn R. Bowles, Edoardo Marcora, Alison M. Goate
Published 2021-01-01

Whole genome sequencing identifies loci specifically associated with thoracic aortic wall defects and abdominal aortic aneurysms in patients with European ancestry

by Grace H. Miner, PhD, Alan E. Renton, PhD, Ella Taubenfeld, BS, Rami O. Tadros, MD, Edoardo Marcora, PhD, Robert A. Lookstein, MD, Peter L. Faries, MD, Michael L. Marin, MD
Published 2020-01-01

Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases

by Manav Kapoor, Michael J. Chao, Emma C. Johnson, Gloriia Novikova, Dongbing Lai, Jacquelyn L. Meyers, Jessica Schulman, John I. Nurnberger, Bernice Porjesz, Yunlong Liu, The Collaborative Study on the Genetics of Alcoholism (COGA), Tatiana Foroud, Howard J. Edenberg, Edoardo Marcora, Arpana Agrawal, Alison Goate
Published 2021-08-01

Integration of Alzheimer’s disease genetics and myeloid genomics identifies disease risk regulatory elements and genes

by Gloriia Novikova, Manav Kapoor, Julia TCW, Edsel M. Abud, Anastasia G. Efthymiou, Steven X. Chen, Haoxiang Cheng, John F. Fullard, Jaroslav Bendl, Yiyuan Liu, Panos Roussos, Johan LM Björkegren, Yunlong Liu, Wayne W. Poon, Ke Hao, Edoardo Marcora, Alison M. Goate
Published 2021-03-01

Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture

by Qian Zhang, Julia Sidorenko, Baptiste Couvy-Duchesne, Riccardo E. Marioni, Margaret J. Wright, Alison M. Goate, Edoardo Marcora, Kuan-lin Huang, Tenielle Porter, Simon M. Laws, Australian Imaging Biomarkers and Lifestyle (AIBL) Study, Perminder S. Sachdev, Karen A. Mather, Nicola J. Armstrong, Anbupalam Thalamuthu, Henry Brodaty, Loic Yengo, Jian Yang, Naomi R. Wray, Allan F. McRae, Peter M. Visscher
Published 2020-09-01