A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replicat...

by Anna Płaszczyca, Pietro Scaturro, Christopher John Neufeldt, Mirko Cortese, Berati Cerikan, Salvatore Ferla, Andrea Brancale, Andreas Pichlmair, Ralf Bartenschlager
Published 2019-05-01

Correction: A Conserved NS3 Surface Patch Orchestrates NS2 Protease Stimulation, NS5A Hyperphosphorylation and HCV Genome Replication.

by Olaf Isken, Ulrike Langerwisch, Vlastimil Jirasko, Dirk Rehders, Lars Redecke, Harish Ramanathan, Brett D Lindenbach, Ralf Bartenschlager, Norbert Tautz
Published 2016-01-01

Effects of NS2B-NS3 protease and furin inhibition on West Nile and Dengue virus replication

by Jenny Kouretova, M. Zouhir Hammamy, Anton Epp, Kornelia Hardes, Stephanie Kallis, Linlin Zhang, Rolf Hilgenfeld, Ralf Bartenschlager, Torsten Steinmetzer
Published 2017-01-01

A conserved NS3 surface patch orchestrates NS2 protease stimulation, NS5A hyperphosphorylation and HCV genome replication.

by Olaf Isken, Ulrike Langerwisch, Vlastimil Jirasko, Dirk Rehders, Lars Redecke, Harish Ramanathan, Brett D Lindenbach, Ralf Bartenschlager, Norbert Tautz
Published 2015-03-01

Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly.

by Nicole Appel, Margarita Zayas, Sven Miller, Jacomine Krijnse-Locker, Torsten Schaller, Peter Friebe, Stephanie Kallis, Ulrike Engel, Ralf Bartenschlager
Published 2008-03-01

MAP-kinase regulated cytosolic phospholipase A2 activity is essential for production of infectious hepatitis C virus particles.

by Nicolas Menzel, Wolfgang Fischl, Kathrin Hueging, Dorothea Bankwitz, Anne Frentzen, Sibylle Haid, Juliane Gentzsch, Lars Kaderali, Ralf Bartenschlager, Thomas Pietschmann
Published 2012-01-01

Correction: Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics

by Artur Kaul, Sarah Stauffer, Carola Berger, Thomas Pertel, Jennifer Schmitt, Stephanie Kallis, Margarita Zayas, Volker Lohmann, Jeremy Luban, Ralf Bartenschlager
Published 2009-09-01

Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics.

by Artur Kaul, Sarah Stauffer, Carola Berger, Thomas Pertel, Jennifer Schmitt, Stephanie Kallis, Margarita Zayas, Volker Lohmann, Jeremy Luban, Ralf Bartenschlager
Published 2009-08-01

Correction: Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics.

by Artur Kaul, Sarah Stauffer, Carola Berger, Thomas Pertel, Jennifer Schmitt, Stephanie Kallis, Margarita Zayas, Volker Lohmann, Jeremy Luban, Ralf Bartenschlager
Published 2009-09-01

Identification of Terfenadine as an Inhibitor of Human CD81-Receptor HCV-E2 Interaction: Synthesis and Structure Optimization

by Rolf W. Hartmann, Christian D. Klein, Lars Kattner, Ralf Bartenschlager, Artur Kaul, Bernd Kronenberger, Beatrice Albrecht, Sigrid Ziegler, Marcel Holzer
Published 2008-05-01

Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus.

by Julia Diegelmann, Florian Beigel, Kathrin Zitzmann, Artur Kaul, Burkhard Göke, Christoph J Auernhammer, Ralf Bartenschlager, Helmut M Diepolder, Stephan Brand
Published 2010-12-01

Lipid droplet quantification based on iterative image processing[S]

by Tarik Exner, Carlo A. Beretta, Qi Gao, Cassian Afting, Inés Romero-Brey, Ralf Bartenschlager, Leonard Fehring, Margarete Poppelreuther, Joachim Füllekrug
Published 2019-07-01

ER-Shaping Atlastin Proteins Act as Central Hubs to Promote Flavivirus Replication and Virion Assembly

by Christopher J Neufeldt, Mirko Cortese, Pietro Scaturro, Berati Cerikan, Jeremy Wideman, Keisuke Tabata, Thais Morase, Olga Oleksiuk, Andreas Pichlmair, Ralf Bartenschlager
Published 2020-06-01

Symmetric Anti-HCV Agents: Synthesis, Antiviral Properties, and Conformational Aspects of Core Scaffolds

by Alaa R. S. Leila, Mai H. A. Mousa, Efseveia Frakolaki, Niki Vassilaki, Ralf Bartenschlager, Grigoris Zoidis, Mohammad Abdel-Halim, Ashraf H. Abadi
Published 2019-07-01

Hepatitis C Virus Activates a Neuregulin-Driven Circuit to Modify Surface Expression of Growth Factor Receptors of the ErbB Family.

by Sabine Stindt, Patricia Cebula, Ute Albrecht, Verena Keitel, Jan Schulte am Esch, Wolfram T Knoefel, Ralf Bartenschlager, Dieter Häussinger, Johannes G Bode
Published 2016-01-01

Production of infectious genotype 1b virus particles in cell culture and impairment by replication enhancing mutations.

by Thomas Pietschmann, Margarita Zayas, Philip Meuleman, Gang Long, Nicole Appel, George Koutsoudakis, Stephanie Kallis, Geert Leroux-Roels, Volker Lohmann, Ralf Bartenschlager
Published 2009-06-01

Hepatitis C virus exploits cyclophilin A to evade PKR

by Che C Colpitts, Sophie Ridewood, Bethany Schneiderman, Justin Warne, Keisuke Tabata, Caitlin F Ng, Ralf Bartenschlager, David L Selwood, Greg J Towers
Published 2020-06-01

Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation.

by Simon Dirmeier, Christopher Dächert, Martijn van Hemert, Ali Tas, Natacha S Ogando, Frank van Kuppeveld, Ralf Bartenschlager, Lars Kaderali, Marco Binder, Niko Beerenwinkel
Published 2020-02-01

The Role of Tissue Oxygen Tension in Dengue Virus Replication

by Efseveia Frakolaki, Panagiota Kaimou, Maria Moraiti, Katerina I. Kalliampakou, Kalliopi Karampetsou, Eleni Dotsika, Panagiotis Liakos, Dido Vassilacopoulou, Penelope Mavromara, Ralf Bartenschlager, Niki Vassilaki
Published 2018-12-01

Erratum for Roth et al., “Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses”

by Hanna Roth, Vera Magg, Fabian Uch, Pascal Mutz, Philipp Klein, Katharina Haneke, Volker Lohmann, Ralf Bartenschlager, Oliver T. Fackler, Nicolas Locker, Georg Stoecklin, Alessia Ruggieri
Published 2017-04-01