Tau Phosphorylation Rates Measured by Mass Spectrometry Differ in the Intracellular Brain vs. Extracellular Cerebrospinal Fluid Compartments and Are Differentially Affected by Alzh...

by Nicolas R. Barthélemy, Nipun Mallipeddi, Paul Moiseyev, Chihiro Sato, Randall J. Bateman, Randall J. Bateman, Randall J. Bateman
Published 2019-05-01

Diurnal oscillation of CSF Aβ and other AD biomarkers

by Brendan P. Lucey, Anne M. Fagan, David M. Holtzman, John C. Morris, Randall J. Bateman
Published 2017-05-01

The informed road map to prevention of Alzheimer Disease: A call to arms

by Eric McDade, Jorge J. Llibre-Guerra, David M. Holtzman, John C. Morris, Randall J. Bateman
Published 2021-07-01

Cerebrospinal fluid phospho-tau T217 outperforms T181 as a biomarker for the differential diagnosis of Alzheimer’s disease and PET amyloid-positive patient identification

by Nicolas R. Barthélemy, Randall J. Bateman, Christophe Hirtz, Philippe Marin, François Becher, Chihiro Sato, Audrey Gabelle, Sylvain Lehmann
Published 2020-03-01

Regional correlation of biochemical measures of amyloid and tau phosphorylation in the brain

by Kanta Horie, Nicolas R. Barthélemy, Nipun Mallipeddi, Yan Li, Erin E. Franklin, Richard J. Perrin, Randall J. Bateman, Chihiro Sato
Published 2020-08-01

Diurnal patterns of soluble amyloid precursor protein metabolites in the human central nervous system.

by Justyna A Dobrowolska, Tom Kasten, Yafei Huang, Tammie L S Benzinger, Wendy Sigurdson, Vitaliy Ovod, John C Morris, Randall J Bateman
Published 2014-01-01

Amyloid-β Plaques in Clinical Alzheimer’s Disease Brain Incorporate Stable Isotope Tracer In Vivo and Exhibit Nanoscale Heterogeneity

by Norelle C. Wildburger, Frank Gyngard, Christelle Guillermier, Christelle Guillermier, Christelle Guillermier, Bruce W. Patterson, Donald Elbert, Kwasi G. Mawuenyega, Theresa Schneider, Karen Green, Robyn Roth, Robyn Roth, Robert E. Schmidt, Nigel J. Cairns, Nigel J. Cairns, Nigel J. Cairns, Nigel J. Cairns, Tammie L. S. Benzinger, Tammie L. S. Benzinger, Tammie L. S. Benzinger, Matthew L. Steinhauser, Matthew L. Steinhauser, Matthew L. Steinhauser, Randall J. Bateman, Randall J. Bateman, Randall J. Bateman
Published 2018-03-01

Microglia Implicated in Tauopathy in the Striatum of Neurodegenerative Disease Patients from Genotype to Phenotype

by Huifangjie Li, William C. Knight, Pengfei Yang, Yingqiu Guo, Joel S. Perlmutter, John C. Morris, Randall J. Bateman, Tammie L. S. Benzinger, Jinbin Xu
Published 2020-08-01

Plasma Aβ and neurofilament light chain are associated with cognitive and physical function decline in non-dementia older adults

by Lingxiao He, Philipe de Souto Barreto, Geetika Aggarwal, Andrew D. Nguyen, John E. Morley, Yan Li, Randall J. Bateman, Bruno Vellas, For the MAPT/DSA Group
Published 2020-10-01

Soluble P‐tau217 reflects amyloid and tau pathology and mediates the association of amyloid with tau

by Niklas Mattsson‐Carlgren, Shorena Janelidze, Randall J Bateman, Ruben Smith, Erik Stomrud, Geidy E Serrano, Eric M Reiman, Sebastian Palmqvist, Jeffrey L Dage, Thomas G Beach, Oskar Hansson
Published 2021-06-01

MAPT R406W increases tau T217 phosphorylation in absence of amyloid pathology

by Chihiro Sato, Nipun Mallipeddi, Nupur Ghoshal, Brenton A. Wright, Gregory S. Day, Albert A. Davis, Albert H. Kim, Gregory J. Zipfel, Randall J. Bateman, Audrey Gabelle, Nicolas R. Barthélemy
Published 2021-09-01

Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer’s disease progression

by Filip Liebsch, Luka Kulic, Charlotte Teunissen, Adeola Shobo, Irem Ulku, Vivienne Engelschalt, Mark A. Hancock, Wiesje M. van der Flier, Peter Kunach, Pedro Rosa-Neto, Philip Scheltens, Judes Poirier, Paul Saftig, Randall J. Bateman, John Breitner, Christoph Hock, Gerhard Multhaup
Published 2019-05-01

A blood-based diagnostic test incorporating plasma Aβ42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: findings from a multi cohort validity analysi...

by Tim West, Kristopher M. Kirmess, Matthew R. Meyer, Mary S. Holubasch, Stephanie S. Knapik, Yan Hu, John H. Contois, Erin N. Jackson, Scott E. Harpstrite, Randall J. Bateman, David M. Holtzman, Philip B. Verghese, Ilana Fogelman, Joel B. Braunstein, Kevin E. Yarasheski
Published 2021-05-01

Correction: In Vivo Human Apolipoprotein E Isoform Fractional Turnover Rates in the CNS

by Kristin R. Wildsmith, Jacob M. Basak, Bruce W. Patterson, Yuriy Pyatkivskyy, Jungsu Kim, Kevin E. Yarasheski, Jennifer X. Wang, Kwasi G. Mawuenyega, Hong Jiang, Maia Parsadanian, Hyejin Yoon, Tom Kasten, Wendy C. Sigurdson, Chengjie Xiong, Alison Goate, David M. Holtzman, Randall J. Bateman
Published 2012-01-01

In vivo human apolipoprotein E isoform fractional turnover rates in the CNS.

by Kristin R Wildsmith, Jacob M Basak, Bruce W Patterson, Yuriy Pyatkivskyy, Jungsu Kim, Kevin E Yarasheski, Jennifer X Wang, Kwasi G Mawuenyega, Hong Jiang, Maia Parsadanian, Hyejin Yoon, Tom Kasten, Wendy C Sigurdson, Chengjie Xiong, Alison Goate, David M Holtzman, Randall J Bateman
Published 2012-01-01

Genetic variants associated with Alzheimer’s disease confer different cerebral cortex cell-type population structure

by Zeran Li, Jorge L. Del-Aguila, Umber Dube, John Budde, Rita Martinez, Kathleen Black, Qingli Xiao, Nigel J. Cairns, The Dominantly Inherited Alzheimer Network (DIAN), Joseph D. Dougherty, Jin-Moo Lee, John C. Morris, Randall J. Bateman, Celeste M. Karch, Carlos Cruchaga, Oscar Harari
Published 2018-06-01

Correction: In Vivo Human Apolipoprotein E Isoform Fractional Turnover Rates in the CNS.

by Kristin R. Wildsmith, Jacob M. Basak, Bruce W. Patterson, Yuriy Pyatkivskyy, Jungsu Kim, Kevin E. Yarasheski, Jennifer X. Wang, Kwasi G. Mawuenyega, Hong Jiang, Maia Parsadanian, Hyejin Yoon, Tom Kasten, Wendy C. Sigurdson, Chengjie Xiong, Alison Goate, David M. Holtzman, Randall J. Bateman
Published 2012-01-01

Diagnostic Value of Subjective Memory Complaints Assessed with a Single Item in Dominantly Inherited Alzheimer’s Disease: Results of the DIAN Study

by Christoph Laske, Hamid R. Sohrabi, Mateusz S. Jasielec, Stephan Müller, Niklas K. Koehler, Susanne Gräber, Stefan Förster, Alexander Drzezga, Felix Mueller-Sarnowski, Adrian Danek, Mathias Jucker, Randall J. Bateman, Virginia Buckles, Andrew J. Saykin, Ralph N. Martins, John C. Morris, Dominantly Inherited Alzheimer Network (DIAN)
Published 2015-01-01

Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network

by Celeste M. Karch, Damián Hernández, Jen-Chyong Wang, Jacob Marsh, Alex W. Hewitt, Simon Hsu, Joanne Norton, Denise Levitch, Tamara Donahue, Wendy Sigurdson, Bernardino Ghetti, Martin Farlow, Jasmeer Chhatwal, Sarah Berman, Carlos Cruchaga, John C. Morris, Randall J. Bateman, the Dominantly Inherited Alzheimer Network (DIAN), Alice Pébay, Alison M. Goate
Published 2018-07-01

The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer’s disease

by Daniel Twohig, Elena Rodriguez-Vieitez, Sigrid B. Sando, Guro Berge, Camilla Lauridsen, Ina Møller, Gøril R. Grøntvedt, Geir Bråthen, Kalicharan Patra, Guojun Bu, Tammie L. S. Benzinger, Celeste M. Karch, Anne Fagan, John C. Morris, Randall J. Bateman, Agneta Nordberg, Linda R. White, Henrietta M. Nielsen, for the Dominantly Inherited Alzheimer Network (DIAN)
Published 2018-11-01