mTOR Signaling in Growth, Metabolism, and Disease

by Saxton, Robert Andrew, Sabatini, David
Published 2018

Growth signaling at the nexus of stem cell life and death

by Wood, Kris C., Sabatini, David
Published 2009

Nutrient mTORC1 signaling underpins regulatory T cell control of immune tolerance

by Efeyan, Alejo, Sabatini, David M.
Published 2020

Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1

by Bar-Peled, Liron, Zoncu, Roberto, Sabatini, David M, Schweitzer, Lawrence David, Sabatini, David
Published 2014

Dietary and Metabolic Control of Stem Cell Function in Physiology and Cancer

by Mihaylova, Maria M, Sabatini, David M, Yilmaz, Omer, Mihaylova, Maria M., Sabatini, David
Published 2016

Myeloid-Specific Rictor Deletion Induces M1 Macrophage Polarization and Potentiates In Vivo Pro-Inflammatory Response to Lipopolysaccharide

by Festuccia, William T., Pouliot, Philippe, Bakan, Inan, Sabatini, David M., Laplante, Mathieu, Sabatini, David M.
Published 2014

mTOR: from growth signal integration to cancer, diabetes and ageing

by Zoncu, Roberto, Efeyan, Alejo, Sabatini, David
Published 2012

A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibility

by Wolfson, Rachel L., Sabatini, David M.
Published 2020

Amino acids and mTORC1: from lysosomes to disease

by Efeyan, Alejo, Zoncu, Roberto, Sabatini, David
Published 2017

Intersubunit Crosstalk in the Rag GTPase Heterodimer Enables mTORC1 to Respond Rapidly to Amino Acid Availability

by Shen, Kuang, Choe, Abigail D., Sabatini, David
Published 2018

Nutrient-Sensing Mechanisms across Evolution

by Chantranupong, Lynne, Wolfson, Rachel Laura, Sabatini, David
Published 2016

Viral Packaging and Cell Culture for CRISPR-Based Screens

by Wang, Tim, Lander, Eric Steven, Sabatini, David
Published 2016

Large-Scale Single Guide RNA Library Construction and Use for CRISPR-Cas9-Based Genetic Screens

by Wang, Tim, Lander, Eric Steven, Sabatini, David
Published 2016

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

by Sengupta, Shomit, Peterson, Timothy Richard, Sabatini, David
Published 2015

Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma

by Sabatini, David, Wolfson, Rachel Laura, Efeyan, Alejo
Published 2017

Single Guide RNA Library Design and Construction

by Wang, Tim, Lander, Eric Steven, Sabatini, David
Published 2016

Activation of PASK by mTORC1 is required for the onset of the terminal differentiation program

by Kang, Seong Anthony Woo, Sabatini, David M.
Published 2020

Rapid immunopurification of mitochondria for metabolite profiling and absolute quantification of matrix metabolites

by Freinkman, Elizaveta, Chen, Walter W., Sabatini, David
Published 2018

Nutrient-sensing mechanisms and pathways

by Efeyan, Alejo, Comb, William C., Sabatini, David
Published 2015

DEPTOR Cell-Autonomously Promotes Adipogenesis, and Its Expression Is Associated with Obesity

by Laplante, Mathieu, Horvat, Simon, Festuccia, William T., Birsoy, Kivanc, Prevorsek, Zala, Efeyan, Alejo, Sabatini, David M, Sabatini, David
Published 2014