Regulation of mTORC1 by amino acids

by Bar-Peled, Liron, Sabatini, David
Published 2017

Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1

by Comb, William C, Schweitzer, Lawrence David, Bar-Peled, Liron, Sabatini, David
Published 2017

Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1

by Bar-Peled, Liron, Zoncu, Roberto, Sabatini, David M, Schweitzer, Lawrence David, Sabatini, David
Published 2014

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

by Sancak, Yasemin, Bar-Peled, Liron, Zoncu, Roberto, Markhard, Andrew L., Nada, Shigeyuki, Sabatini, David
Published 2012

The Folliculin Tumor Suppressor Is a GAP for the RagC/D GTPases That Signal Amino Acid Levels to mTORC1

by Spooner, Eric, Tsun, Zhi-Yang, Bar-Peled, Liron, Chantranupong, Lynne, Zoncu, Roberto, Wang, Tim, Kim, Choah, Sabatini, David
Published 2017

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

by Zoncu, Roberto, Bar-Peled, Liron, Efeyan, Alejo, Sancak, Yasemin, Sabatini, David M., Wang, Shuyu, Ph. D. Massachusetts Institute of Technology
Published 2015

A Tumor Suppressor Complex with GAP Activity for the Rag GTPases That Signal Amino Acid Sufficiency to mTORC1

by Bar-Peled, Liron, Chantranupong, Lynne, Cherniack, Andrew D., Chen, Walter W., Ottina, Kathleen, Grabiner, Brian C., Spear, Eric D., Carter, Scott L., Meyerson, Matthew L., Sabatini, David M.
Published 2014

The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1

by Chantranupong, Lynne, Orozco, Jose M, Scaria, Sonia M, Bar-Peled, Liron, Spooner, Eric, Isasa, Marta, Gygi, Steven P., Sabatini, David M, Wolfson, Rachel Laura, Saxton, Robert Andrew, Scaria, Sonia M., Sabatini, David
Published 2015

Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1

by Plovanich, M. E., Straub, C., Sabatini, B. L., Tsun, Zhi-Yang, Wang, Shuyu, Wolfson, Rachel Laura, Shen, Kuang, Wyant, Gregory Andrew, Yuan, Elizabeth D., Jones, Tony D., Chantranupong, Lynne, Comb, William C., Wang, Tim, Bar-Peled, Liron, Zoncu, Roberto, Kim, Choah, Park, Jiwon, Sabatini, David
Published 2015