Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

by Sancak, Yasemin, Bar-Peled, Liron, Zoncu, Roberto, Markhard, Andrew L., Nada, Shigeyuki, Sabatini, David
Published 2012

Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a Highly Potent, Selective Mammalian Target of Rapa...

by Liu, Qingsong, Chang, Jae Won, Wang, Jinhua, Kang, Seong A., Thoreen, Carson C., Markhard, Andrew L., Hur, Wooyoung, Zhang, Jianming, Sim, Taebo, Gray, Nathanael S., Sabatini, David
Published 2014