Rag proteins regulate amino-acid-induced mTORC1 signalling

by Sancak, Yasemin, Sabatini, David
Published 2011

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

by Sancak, Yasemin, Bar-Peled, Liron, Zoncu, Roberto, Markhard, Andrew L., Nada, Shigeyuki, Sabatini, David
Published 2012

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

by Zoncu, Roberto, Bar-Peled, Liron, Efeyan, Alejo, Sancak, Yasemin, Sabatini, David M., Wang, Shuyu, Ph. D. Massachusetts Institute of Technology
Published 2015

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

by Peterson, Timothy R., Laplante, Mathieu, Thoreen, Carson C., Sancak, Yasemin, Kang, Seong A., Kuehl, W. Michael, Gray, Nathanael S., Sabatini, David M.
Published 2015

Engineered ascorbate peroxidase as a genetically encoded reporter for electron microscopy

by Deerinck, Thomas J., Sancak, Yasemin, Poulos, Thomas L., Mootha, Vamsi K., Sosinsky, Gina E., Ellisman, Mark H., Martell, Jeffrey Daniel, Ting, Alice Y.
Published 2015

MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling

by Plovanich, Molly, Bogorad, Roman, Sancak, Yasemin, Kamer, Kimberli J., Strittmatter, Laura, Li, Andrew A., Girgis, Hany S., Kuchimanchi, Satya, Groot, Jack De, Speciner, Lauren, Taneja, Nathan, OShea, Jonathan, Kotelianski, Victor E., Mootha, Vamsi K.
Published 2013

Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome

by DeKelver, Russell C., Choi, Vivian M., Moehle, Erica A., Paschon, David E., Hockemeyer, Dirk, Meijsing, Sebastiaan H., Sancak, Yasemin, Cui, Xiaoxia, Steine, Eveline J., Miller, Jeffrey C., Tam, Phillip, Bartsevich, Victor V., Meng, Xiangdong, Rupniewski, Igor, Gopalan, Sunita M., Sun, Helena C., Pitz, Kathleen J., Rock, Jeremy M., Davis, Gregory D., Rebar, Edward J., Yamamoto, Keith R., Jaenisch, Rudolf, Gregory, Philip D., Urnov, Fyodor D., Zhang, Lei, Ph. D Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, fl. 2014, Cheeseman, Iain M, Sabatini, David
Published 2012