Epigenome-wide DNA methylation in hearing ability: new mechanisms for an old problem.

by Lisa E Wolber, Claire J Steves, Pei-Chien Tsai, Panos Deloukas, Tim D Spector, Jordana T Bell, Frances M K Williams
Published 2014-01-01

Use of dietary indices to control for diet in human gut microbiota studies

by Ruth C. E. Bowyer, Matthew A. Jackson, Tess Pallister, Jane Skinner, Tim D. Spector, Ailsa A. Welch, Claire J. Steves
Published 2018-04-01

Molecular pathways associated with blood pressure and hexadecanedioate levels.

by Cristina Menni, Sarah J Metrustry, Georg Ehret, Anna F Dominiczak, Phil Chowienczyk, Tim D Spector, Sandosh Padmanabhan, Ana M Valdes
Published 2017-01-01

Serum Lipid Levels and Risk Of Hand Osteoarthritis: The Chingford Prospective Cohort Study

by M. Garcia-Gil, C. Reyes, R. Ramos, M. T. Sanchez-Santos, D. Prieto-Alhambra, T. D. Spector, D. J. Hart, N. K. Arden
Published 2017-06-01

Characterizing Blood Metabolomics Profiles Associated with Self-Reported Food Intakes in Female Twins.

by Tess Pallister, Amy Jennings, Robert P Mohney, Darioush Yarand, Massimo Mangino, Aedin Cassidy, Alexander MacGregor, Tim D Spector, Cristina Menni
Published 2016-01-01

A twin study of mitochondrial DNA polymorphisms shows that heteroplasmy at multiple sites is associated with mtDNA variant 16093 but not with zygosity.

by Toby Andrew, Cassandra D Calloway, Sarah Stuart, Sang Hoon Lee, Raj Gill, Gail Clement, Philip Chowienczyk, Tim D Spector, Ana M Valdes
Published 2011-01-01

Generalised Anxiety Disorder--A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression.

by Matthew N Davies, Serena Verdi, Andrea Burri, Maciej Trzaskowski, Minyoung Lee, John M Hettema, Rick Jansen, Dorret I Boomsma, Tim D Spector
Published 2015-01-01

Genetic Influences on Metabolite Levels: A Comparison across Metabolomic Platforms.

by Idil Yet, Cristina Menni, So-Youn Shin, Massimo Mangino, Nicole Soranzo, Jerzy Adamski, Karsten Suhre, Tim D Spector, Gabi Kastenmüller, Jordana T Bell
Published 2016-01-01

Socioeconomic Status and the Gut Microbiome: A TwinsUK Cohort Study

by Ruth C. E. Bowyer, Matthew A. Jackson, Caroline I. Le Roy, Mary Ni Lochlainn, Tim D. Spector, Jennifer B. Dowd, Claire J. Steves
Published 2019-01-01

Genetic interactions affecting human gene expression identified by variance association mapping

by Andrew Anand Brown, Alfonso Buil, Ana Viñuela, Tuuli Lappalainen, Hou-Feng Zheng, J Brent Richards, Kerrin S Small, Timothy D Spector, Emmanouil T Dermitzakis, Richard Durbin
Published 2014-04-01

MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies.

by Toomas Haller, Liis Leitsalu, Krista Fischer, Marja-Liisa Nuotio, Tõnu Esko, Dorothea Irene Boomsma, Kirsten Ohm Kyvik, Tim D Spector, Markus Perola, Andres Metspalu
Published 2017-01-01

Circulating Levels of the Short-Chain Fatty Acid Acetate Mediate the Effect of the Gut Microbiome on Visceral Fat

by Ana Nogal, Panayiotis Louca, Xinyuan Zhang, Philippa M. Wells, Claire J. Steves, Tim D. Spector, Mario Falchi, Ana M. Valdes, Ana M. Valdes, Cristina Menni
Published 2021-07-01

Dietary Interventions Reduce Traditional and Novel Cardiovascular Risk Markers by Altering the Gut Microbiome and Their Metabolites

by Amrita Vijay, Amrita Vijay, Stuart Astbury, Louca Panayiotis, Francine Z. Marques, Francine Z. Marques, Tim D. Spector, Cristina Menni, Ana M. Valdes, Ana M. Valdes
Published 2021-07-01

Acetaminophen (Paracetamol) Use Modifies the Sulfation of Sex Hormones

by Isaac V. Cohen, Elizabeth T. Cirulli, Matthew W. Mitchell, Thomas J. Jonsson, James Yu, Naisha Shah, Tim D. Spector, Lining Guo, J. Craig Venter, Amalio Telenti
Published 2018-02-01

A metagenome-wide association study of gut microbiota in asthma in UK adults

by Qi Wang, Fei Li, Bishan Liang, Yuhu Liang, Sijie Chen, Xiaodong Mo, Yanmei Ju, Hui Zhao, Huijue Jia, Timothy D. Spector, Hailiang Xie, Ruijin Guo
Published 2018-09-01

Gut-Microbiota-Metabolite Axis in Early Renal Function Decline.

by Clara Barrios, Michelle Beaumont, Tess Pallister, Judith Villar, Julia K Goodrich, Andrew Clark, Julio Pascual, Ruth E Ley, Tim D Spector, Jordana T Bell, Cristina Menni
Published 2015-01-01

SMAD3 is associated with the total burden of radiographic osteoarthritis: the Chingford study.

by Erfan Aref-Eshghi, Yuhua Zhang, Deborah Hart, Ana M Valdes, Andrew Furey, Glynn Martin, Guang Sun, Proton Rahman, Nigel Arden, Tim D Spector, Guangju Zhai
Published 2014-01-01

Detection of stable community structures within gut microbiota co-occurrence networks from different human populations

by Matthew A. Jackson, Marc Jan Bonder, Zhana Kuncheva, Jonas Zierer, Jingyuan Fu, Alexander Kurilshikov, Cisca Wijmenga, Alexandra Zhernakova, Jordana T. Bell, Tim D. Spector, Claire J. Steves
Published 2018-02-01

The incidence and characteristics of accelerated knee osteoarthritis among women: the Chingford cohort

by Jeffrey B. Driban, Raveendhara R. Bannuru, Charles B. Eaton, Tim D. Spector, Deborah J. Hart, Timothy E. McAlindon, Bing Lu, Grace H. Lo, Nigel K. Arden
Published 2020-01-01

Ascorbic acid metabolites are involved in intraocular pressure control in the general population

by Pirro G. Hysi, Anthony P. Khawaja, Cristina Menni, Bani Tamraz, Nick Wareham, Kay-Tee Khaw, Paul J. Foster, Leslie Z. Benet, Tim D. Spector, Chris J. Hammond
Published 2019-01-01