Aspirin Prevents Colorectal Cancer by Normalizing EGFR Expression

by Haitao Li, Feng Zhu, Lisa A. Boardman, Lei Wang, Naomi Oi, Kangdong Liu, Xiang Li, Yang Fu, Paul J. Limburg, Ann M. Bode, Zigang Dong
Published 2015-05-01

The Daidzein Metabolite, 6,7,4'-Trihydroxyisoflavone, Is a Novel Inhibitor of PKCα in Suppressing Solar UV-Induced Matrix Metalloproteinase 1

by Tae-Gyu Lim, Jong-Eun Kim, Sung-Young Lee, Jun Seong Park, Myung Hun Yeom, Hanyong Chen, Ann M. Bode, Zigang Dong, Ki Won Lee
Published 2014-11-01

Cytokine Signature Induced by SARS-CoV-2 Spike Protein in a Mouse Model

by Tingxuan Gu, Tingxuan Gu, Simin Zhao, Simin Zhao, Guoguo Jin, Guoguo Jin, Mengqiu Song, Mengqiu Song, Yafei Zhi, Ran Zhao, Ran Zhao, Fayang Ma, Fayang Ma, Yaqiu Zheng, Keke Wang, Hui Liu, Hui Liu, Mingxia Xin, Wei Han, Xiang Li, Xiang Li, Xiang Li, Christopher D. Dong, Kangdong Liu, Kangdong Liu, Kangdong Liu, Zigang Dong, Zigang Dong
Published 2021-01-01

Serine 347 Phosphorylation by JNKs Negatively Regulates OCT4 Protein Stability in Mouse Embryonic Stem Cells

by Ki Beom Bae, Dong Hoon Yu, Kun Yeong Lee, Ke Yao, Joohyun Ryu, Do Young Lim, Tatyana A. Zykova, Myoung Ok Kim, Ann M. Bode, Zigang Dong
Published 2017-12-01

The ginsenoside 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol induces autophagy and apoptosis in human melanoma via AMPK/JNK phosphorylation.

by Soouk Kang, Jong-Eun Kim, Nu Ry Song, Sung Keun Jung, Mee Hyun Lee, Jun Seong Park, Myeong-Hun Yeom, Ann M Bode, Zigang Dong, Ki Won Lee
Published 2014-01-01

Functional PIN1 promoter polymorphisms associated with risk of nasopharyngeal carcinoma in Southern Chinese populations

by Liuyan Zeng, Shengqun Luo, Xin Li, Mengxuan Lu, Huahui Li, Tong Li, Guanhua Wang, Xiaoming Lyu, Wenrui Jia, Zigang Dong, Qiang Jiang, Zhihua Shen, Guo-Liang Huang, Zhiwei He
Published 2017-07-01

Benzyl Isothiocyanate Inhibits Prostate Cancer Development in the Transgenic Adenocarcinoma Mouse Prostate (TRAMP) Model, Which Is Associated with the Induction of Cell Cycle G1 Ar...

by Han Jin Cho, Do Young Lim, Gyoo Taik Kwon, Ji Hee Kim, Zunnan Huang, Hyerim Song, Yoon Sin Oh, Young-Hee Kang, Ki Won Lee, Zigang Dong, Jung Han Yoon Park
Published 2016-02-01

Inhibiting breast cancer by targeting the thromboxane A2 pathway

by Haitao Li, Mee-Hyun Lee, Kangdong Liu, Ting Wang, Mengqiu Song, Yaping Han, Ke Yao, Hua Xie, Feng Zhu, Michael Grossmann, Margot P. Cleary, Wei Chen, Ann M. Bode, Zigang Dong
Published 2017-04-01

Inhibition of LTA4H by bestatin in human and mouse colorectal cancerResearch in context

by Simin Zhao, Ke Yao, Dan Li, Kangdong Liu, Guoguo Jin, Mingyang Yan, Qiong Wu, Hanyong Chen, Seung Ho Shin, Ruihua Bai, Gangcheng Wang, Ann M. Bode, Ziming Dong, Zhiping Guo, Zigang Dong
Published 2019-06-01

Targeting the COX1/2-Driven thromboxane A2 pathway suppresses Barrett's esophagus and esophageal adenocarcinoma developmentResearch in context

by Tianshun Zhang, Qiushi Wang, Wei-Ya Ma, Keke Wang, Xiaoyu Chang, Michele L. Johnson, Ruihua Bai, Ann M. Bode, Nathan R. Foster, Gary W. Falk, Paul J. Limburg, Prasad G. Iyer, Zigang Dong
Published 2019-11-01

A Small Molecule Inhibitor of the β-Catenin-TCF4 Interaction Suppresses Colorectal Cancer Growth In Vitro and In Vivo

by Seung Ho Shin, Do Young Lim, Kanamata Reddy, Margarita Malakhova, Fangfang Liu, Ting Wang, Mengqiu Song, Hanyong Chen, Ki Beom Bae, Joohyun Ryu, Kangdong Liu, Mee-Hyun Lee, Ann M. Bode, Zigang Dong
Published 2017-11-01

Autophagy and cellular senescence mediated by Sox2 suppress malignancy of cancer cells.

by Yong-Yeon Cho, Dong Joon Kim, Hye Suk Lee, Chul-Ho Jeong, Eun-Jin Cho, Myong-Ok Kim, Sanguine Byun, Kun-Yeong Lee, Ke Yao, Andria Carper, Alyssa Langfald, Ann M Bode, Zigang Dong
Published 2013-01-01

JNK1 and 2 play a negative role in reprogramming to pluripotent stem cells by suppressing Klf4 activity

by Ke Yao, Myoung Ok Ki, Hanyong Chen, Yong-Yeon Cho, Sung-Hyun Kim, Dong Hoon Yu, Sung-Young Lee, Kun-Yeong Lee, Kibeom Bae, Cong Peng, Do Young Lim, Ann M. Bode, Zigang Dong
Published 2014-01-01

7,3′,4′-Trihydroxyisoflavone, a Metabolite of the Soy Isoflavone Daidzein, Suppresses α-Melanocyte-Stimulating Hormone-Induced Melanogenesis by Targeting Melanocortin 1 Receptor...

by Ji Hye Kim, Ji Hye Kim, Jae-Eun Lee, Taewon Kim, Myung Hun Yeom, Jun Seong Park, Eric di Luccio, Hanyong Chen, Zigang Dong, Ki Won Lee, Ki Won Lee, Ki Won Lee, Nam Joo Kang
Published 2020-12-01

The function of heterodimeric AP-1 comprised of c-Jun and c-Fos in activin mediated Spemann organizer gene expression.

by Sung-Young Lee, Jaeho Yoon, Hyun-Shik Lee, Yoo-Seok Hwang, Sang-Wook Cha, Chul-Ho Jeong, Jong-Il Kim, Jae-Bong Park, Jae-Yong Lee, SungChan Kim, Mae Ja Park, Zigang Dong, Jaebong Kim
Published 2011-01-01

Rhein Suppresses Colorectal Cancer Cell Growth by Inhibiting the mTOR Pathway In Vitro and In Vivo

by Haibo Zhang, Jun-Koo Yi, Hai Huang, Song Park, Sijun Park, Wookbong Kwon, Eungyung Kim, Soyoung Jang, Si-Yong Kim, Seong-Kyoon Choi, Sung-Hyun Kim, Kangdong Liu, Zigang Dong, Zae Young Ryoo, Myoung Ok Kim
Published 2021-04-01

Targeting AKT with costunolide suppresses the growth of colorectal cancer cells and induces apoptosis in vitro and in vivo

by Hai Huang, Song Park, Haibo Zhang, Sijun Park, Wookbong Kwon, Enugyung Kim, Xiujuan Zhang, Soyoung Jang, Duhak Yoon, Seong-Kyoon Choi, Jun-koo Yi, Sung-hyun Kim, Zigang Dong, Mee-hyun Lee, Zaeyoung Ryoo, Myoung Ok Kim
Published 2021-03-01

ERK1 phosphorylates Nanog to regulate protein stability and stem cell self-renewal

by Sung-Hyun Kim, Myoung Ok Kim, Yong-Yeon Cho, Ke Yao, Dong Joon Kim, Chul-Ho Jeong, Dong Hoon Yu, Ki Beom Bae, Eun Jin Cho, Sung Keun Jung, Mee Hyun Lee, Hanyong Chen, Jae Young Kim, Ann M. Bode, Zigang Dong
Published 2014-07-01